Interesting facts
Interesting Facts about 5-Nitro-1H-Imidazole
5-Nitro-1H-imidazole is a fascinating chemical compound that showcases the intricate world of heterocyclic chemistry. Here are some noteworthy aspects:
- Biological Importance: This compound plays a significant role in medicinal chemistry. Its derivatives are known for their antimicrobial and antiprotozoal activities, making it a point of interest for drug development.
- Structure and Stability: The nitro group (-NO2) enhances the stability of the imidazole ring, contributing to its reactivity and potential applications in synthesis.
- Versatile Reactions: Due to the presence of both nitrogen atoms in its structure, 5-nitro-1H-imidazole is amenable to a variety of chemical reactions, such as nucleophilic substitutions and coupling reactions.
- Research Applications: As a chemical probe, it is utilized in research to understand enzyme mechanisms and interactions at the molecular level, providing insights into biochemical pathways.
- Historical Context: Imidazole derivatives, including 5-nitro-1H-imidazole, have been studied since the mid-20th century, highlighting the ongoing interest in their properties and potential therapeutic uses.
In summary, 5-nitro-1H-imidazole not only serves as a building block in the development of various pharmaceuticals but also offers a rich field of study for chemists focusing on organic synthesis and biological applications. Its unique structure and reactivity present numerous opportunities for innovation in therapeutic strategies.
Synonyms
4-Nitroimidazole
3034-38-6
5-Nitro-1H-imidazole
5-Nitroimidazole
1H-Imidazole, 4-nitro-
1H-Imidazole, 5-nitro-
4(5)-Nitroimidazole
Imidazole, 4-nitro-
4-nitro-3H-imidazole
1H-5-Nitroimidazole
5(4)-nitroimidazole
EINECS 221-224-7
NSC 50359
Imidazole, 4(or 5)-nitro-
Y8U32AZ5O7
CHEBI:64635
AI3-60154
NSC-50359
NITROIMIDAZOLE, 4-
DTXSID9062803
EC 221-224-7
DTXCID0038174
221-224-7
inchi=1/c3h3n3o2/c7-6(8)3-1-4-2-5-3/h1-2h,(h,4,5
4-NITRO-1H-IMIDAZOLE
100214-79-7
MFCD00005196
CL 205086 (9CI)
imidazole, 4(5)-nitro-
1H-4-Nitroimidazole
UNII-Y8U32AZ5O7
4-nitro-imidazole
CL 205086
4-Nitroimidazole, 97%
SCHEMBL44903
MLS001304931
CHEMBL135599
HMS2234E17
HMS3374L01
METRONIDAZOLE EP IMPURITY B
BCP32907
NSC50359
STR08114
BBL027506
STK793006
AKOS000561522
AKOS003613147
AC-1213
CS-W019995
FN14780
PS-4383
NCGC00247072-01
HY-78644
SMR000420248
SY001473
DB-002578
DB-219580
N0506
NS00006701
EN300-27185
E80412
AB00374225-05
AB00374225-07
4-Nitroimidazole, Vetec(TM) reagent grade, 97%
AB-323/25048517
AB-337/25021026
AJ-030/25007190
F1791-0019
Z235345333
Metronidazole IMpurtiy B; 5-nitro-1H-imidazole;1H-Imidazole, 4-nitro-
Solubility of 5-nitro-1H-imidazole
5-nitro-1H-imidazole, a compound known for its unique aromatic structure, has specific solubility characteristics that are important for its applications.
Its solubility properties can be summarized as follows:
In conclusion, understanding the solubility of 5-nitro-1H-imidazole is crucial for its utilization in chemical synthesis and other applications, especially in contexts where solvent selection is paramount for achieving optimal results.