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(5-nitro-2-furyl)methanol

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Identification
Molecular formula
C5H5NO4
CAS number
655-27-2
IUPAC name
(5-nitro-2-furyl)methanol
State
State

At room temperature, (5-nitro-2-furyl)methanol is a solid. It is non-volatile under standard laboratory conditions and must be handled with care due to its potential sensitivity to light and humidity.

Melting point (Celsius)
69.00
Melting point (Kelvin)
342.15
Boiling point (Celsius)
237.00
Boiling point (Kelvin)
510.15
General information
Molecular weight
157.11g/mol
Molar mass
157.1260g/mol
Density
1.5040g/cm3
Appearence

(5-Nitro-2-furyl)methanol appears as a pale yellow crystalline solid. It is typically handled in the form of powder or small crystals, noteworthy for its slight yellow hue, which is indicative of its nitro functional group. The compound is sensitive to light and should be stored in a light-resistant container to prevent degradation.

Comment on solubility

Solubility of (5-nitro-2-furyl)methanol

(5-nitro-2-furyl)methanol, with its unique structure, exhibits interesting solubility characteristics. This compound is expected to be:

  • Moderately soluble in polar solvents such as water due to its hydroxyl (-OH) functionality, which can form hydrogen bonds.
  • More soluble in organic solvents like ethanol or methanol, which can stabilize its polar characteristics.
  • Relatively insoluble in non-polar solvents, owing to its considerable polarity and electron-withdrawing nitro group, which discourage interactions with non-polar molecules.

In general, factors affecting the solubility of (5-nitro-2-furyl)methanol include:

  • Temperature: Higher temperatures often increase solubility, allowing the compound to include more solvent interactions.
  • Solvent polarity: The choice of solvent will significantly determine the degree of solubility due to intermolecular forces.
  • pH levels: Changes in pH may influence the protonation state of the compound, thereby affecting solubility.

Overall, understanding the solubility of (5-nitro-2-furyl)methanol is crucial for its applications and behavior in various chemical environments. Its solubility factors make it a versatile compound for further studies and practical applications.

Interesting facts

Interesting Facts about (5-nitro-2-furyl)methanol

(5-nitro-2-furyl)methanol is a fascinating compound that showcases the intersection of chemistry and functional applications. Here are some intriguing aspects of this compound:

  • Versatile Solvent: This compound is known for its unique properties that make it useful as a solvent and reagent in organic synthesis. Its effective solvating ability allows chemists to conduct a variety of reactions smoothly.
  • Biological Activity: Research has shown that compounds like (5-nitro-2-furyl)methanol may exhibit interesting biological activities. For example, derivatives of nitrofuran compounds have been investigated for their antimicrobial properties, providing potential leads in pharmaceutical development.
  • Synthetic Pathways: The synthesis of this compound can be intriguing. There are multiple methodological approaches to synthesizing (5-nitro-2-furyl)methanol, from the nitration of furan derivatives to more complex multi-step synthesis processes. Understanding these pathways can significantly enrich a chemist's synthetic repertoire.
  • Environmental Considerations: As with many nitro compounds, it is important to consider the environmental impact and toxicity profiles. The study of (5-nitro-2-furyl)methanol includes discussions regarding its degradation and potential by-products, which is essential for maintaining sustainable chemical practices.
  • Applications in Research: This compound plays a role in theoretical and practical chemistry studies. Its reactivity and behavior in various reactions provide insights into reaction mechanisms, making it a valuable subject in educational contexts and higher-level research.

In summary, (5-nitro-2-furyl)methanol stands out due to its multifaceted roles in organic chemistry, potential medicinal applications, and contribution to sustainability discussions in the field. As the journey of uncovering its properties and applications continues, it remains a notable compound in the realm of chemical science.

Synonyms
5-Nitrofurfuryl alcohol
2493-04-1
FURFURYL ALCOHOL, 5-NITRO-
AI3-23604
NSC 6454
BRN 0123848
DTXSID60179640
Furan, 2-hydroxymethyl-5-nitro-
5-17-03-00350 (Beilstein Handbook Reference)
DTXCID20102131
624-864-9
ndstuupexncunw-uhfffaoysa-n
(5-nitrofuran-2-yl)methanol
2-Furanmethanol, 5-nitro-
5-Nitro-2-furanmethanol
2-Furfuryl alcohol, 5-nitro-
NSC-6454
2-Hydroxymethyl-5-nitrofuran
5-nitrofurfurol
5-nitro-furfurol
NSC6454
MFCD00272267
(5-Nitro-2-furyl)methanol #
SCHEMBL1977597
SD64757V5Y
5-Nitrofurfuryl alcohol,tech. grade
AKOS009097859
AKOS015916462
AS-58595
DB-067282
CS-0147463
5-Nitrofurfuryl alcohol, technical grade, 90%
D81735