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5-Nitroisophthalic acid

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Identification
Molecular formula
C8H5NO6
CAS number
618-88-2
IUPAC name
5-nitrobenzene-1,3-dicarboxylic acid
State
State

At room temperature, 5-Nitroisophthalic acid is typically in a solid state. It is stable under normal conditions and can exist as crystalline powder.

Melting point (Celsius)
348.00
Melting point (Kelvin)
621.00
Boiling point (Celsius)
700.00
Boiling point (Kelvin)
973.00
General information
Molecular weight
211.13g/mol
Molar mass
211.1210g/mol
Density
1.6170g/cm3
Appearence

5-Nitroisophthalic acid typically appears as a light yellow crystalline solid. Its solid form can vary slightly in color intensity, and it usually presents as a powder or small crystals.

Comment on solubility

Solubility of 5-nitrobenzene-1,3-dicarboxylic acid

The solubility of 5-nitrobenzene-1,3-dicarboxylic acid (C9H7N1O4) in various solvents can be quite interesting. This compound, known for its dicarboxylic properties, shows a range of solubility behaviors based on the environment:

  • Water: Generally, 5-nitrobenzene-1,3-dicarboxylic acid has low solubility in water due to its larger hydrophobic aromatic structure, which impedes interaction with polar water molecules.
  • Organic Solvents: It tends to be more soluble in organic solvents such as ethanol, acetone, and dimethyl sulfoxide (DMSO), which can solvate its nonpolar regions effectively.
  • pH Dependency: The solubility can also be affected by pH; in basic conditions, the carboxylic acid groups can deprotonate, potentially increasing solubility through ionization.

In conclusion, the solubility of 5-nitrobenzene-1,3-dicarboxylic acid is influenced by factors such as solvent type and pH levels. As emphasized, understanding these properties is essential for its practical applications in chemical synthesis and industrial processes.

Interesting facts

Interesting Facts about 5-Nitrobenzene-1,3-dicarboxylic acid

5-Nitrobenzene-1,3-dicarboxylic acid is a fascinating compound with several significant applications and noteworthy properties in the realm of organic chemistry. This compound is characterized by two carboxylic acid groups and a nitro group, making it an interesting subject of study.

Key Characteristics:

  • Intermediate in Synthesis: This compound serves as an important intermediate in the synthesis of various pharmaceuticals and agrochemicals.
  • Esterification Reactions: Its dicarboxylic acid functionality allows for esterification reactions, which are crucial in polymer chemistry.
  • Presence of Nitro Group: The nitro (–NO2) group enhances electron-withdrawing properties, making the compound more reactive in electrophilic substitution reactions.

Applications in Research:

Researchers have shown interest in 5-nitrobenzene-1,3-dicarboxylic acid due to its potential as a building block in organic synthesis. It's often used in the creation of:

  • Complex organic molecules
  • Functional materials
  • Biologically active compounds

Environmental Considerations:

As with many nitro-substituted compounds, considerations regarding the environmental impact and toxicity are essential. It is crucial to handle this compound with care and to follow safety protocols during experimentation.

In summary, 5-nitrobenzene-1,3-dicarboxylic acid is not just a mere compound, but a stepping stone into the broader fields of organic synthesis and material science. As with many compounds in chemistry, understanding its unique properties and potential applications can lead to innovative discoveries.

Synonyms
5-Nitroisophthalic acid
5-Nitrobenzene-1,3-dicarboxylic acid
5-Nitro-1,3-benzenedicarboxylic acid
5-NITRO-M-PHTHALIC ACID
Isophthalic acid, 5-nitro-
1,3-Benzenedicarboxylic acid, 5-nitro-
1-Nitrobenzene-3,5-dicarboxylic acid
UNII-G7RZ7LC76U
G7RZ7LC76U
NSC 66545
DTXSID7041540
EINECS 210-568-3
NSC-66545
DTXCID5021540
NBDAHKQJXVLAID-UHFFFAOYSA-
EC 210-568-3
GLYCOPYRRONIUM BROMIDE IMPURITY O [EP IMPURITY]
GLYCOPYRRONIUM BROMIDE IMPURITY O (EP IMPURITY)
Isophthalic acid, 5-nitro-(8CI)
210-568-3
inchi=1/c8h5no6/c10-7(11)4-1-5(8(12)13)3-6(2-4)9(14)15/h1-3h,(h,10,11)(h,12,13)
nbdahkqjxvlaid-uhfffaoysa-n
618-88-2
MFCD00007254
5-Nitroisophthalicacid
5-Nitro-1,3-benzenedicarboxylic acid; 1-Nitrobenzene-3,5-dicarboxylic acid; 5-Nitro-m-phthalic acid; 5-Nitroisophthalic acid; NSC 66545
5-nitroisophtalic acid
5-nitroisopthalic acid
5-nitro-isophthalic acid
SCHEMBL232779
5-Nitroisophthalic acid, 98%
CHEMBL2179899
SCHEMBL19245496
BCP31127
NSC66545
Tox21_300768
STK498488
AKOS000283439
AC-8407
FN62858
NCGC00248162-01
NCGC00254672-01
AS-11792
CAS-618-88-2
CS-0020271
N0520
NS00001706
E80888
EN300-136844
Q27278901
5-Nitroisophthalic acid, Vetec(TM) reagent grade, 98%
F8881-4399
Z276653386
Isophthalic acid, 5-nitro-;5-Nitro-1,3-benzenedicarboxylic acid