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5-Nitrofurfural oxime

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Identification
Molecular formula
C5H4N2O4
CAS number
4114-28-7
IUPAC name
5-nitrofuran-2-carbaldehyde oxime
State
State

At room temperature, 5-nitrofuran-2-carbaldehyde oxime is in the solid state. It is typically present as a crystalline powder.

Melting point (Celsius)
154.00
Melting point (Kelvin)
427.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
156.10g/mol
Molar mass
156.1040g/mol
Density
1.4000g/cm3
Appearence

5-Nitrofuran-2-carbaldehyde oxime generally appears as a yellow crystalline solid. The crystals are typically needle-like or may form a powder form, displaying a vibrant yellow hue.

Comment on solubility

Solubility of 5-nitrofuran-2-carbaldehyde oxime

5-nitrofuran-2-carbaldehyde oxime, with its unique structure, exhibits interesting solubility characteristics. Understanding its solubility is crucial for applications in chemical synthesis and medicinal chemistry. Here are some key points to consider:

  • Solvent Compatibility: This compound is generally soluble in polar solvents such as ethanol and methanol. However, its solubility in non-polar solvents can be limited.
  • Hydrophilicity: The presence of the nitro group and the oxime functional group contributes to its hydrophilic nature, enhancing its ability to interact with water molecules.
  • Temperature Effects: Like many organic compounds, solubility can increase with temperature, making it important to consider when dissolving this compound for reactions or analyses.

As you experiment with 5-nitrofuran-2-carbaldehyde oxime, remember that “like dissolves like”; thus, selecting appropriate solvents is key for achieving optimal solubility.

Interesting facts

Interesting Facts about 5-Nitrofuran-2-carbaldehyde oxime

5-Nitrofuran-2-carbaldehyde oxime is a significant compound in the field of organic chemistry, particularly noted for its diverse applications. Here are some key points that highlight its importance:

  • Structural Importance: The compound features a nitrofuran ring, which is a versatile moiety that plays a crucial role in various chemical reactions. This characteristic often makes it a target for pharmaceutical research.
  • Biological Activity: Compounds containing the furan ring, especially those with a nitro group, are known for their biological reactivity. They can exhibit antimicrobial and anticancer properties, making them valuable in medicinal chemistry.
  • Synthetic Versatility: The oxime functional group present in 5-nitrofuran-2-carbaldehyde oxime can easily participate in further chemical transformations, leading to a variety of derivatives which can be employed in synthesizing new drugs.
  • Research Applications: This compound serves as a building block for more complex molecules and is often utilized in the development of agrochemicals and pharmaceuticals, showcasing its applicability in multiple sectors.
  • Environmental Monitoring: The nitro group may also lend itself to studies in environmental chemistry, specifically in tracking nitro compounds and their behavior in different ecosystems.

In summary, 5-nitrofuran-2-carbaldehyde oxime is not just a simple compound; it is a gateway to innovative synthetic routes and therapeutic potential. The presence of both the nitro and oxime functional groups allows it to be a fascinating subject of study for chemists aiming to create new and effective chemical entities. As noted by many researchers, its varied applications demonstrate the vast possibilities that a single compound can offer in both academic and industrial settings.

Synonyms
2-Furancarboxaldehyde, 5-nitro-, oxime, (Z)-
2-Furancarboxaldehyde, 5-nitro-, oxime, (Z)-(9CI)
Nifuroxime
Micofur
N-[(5-nitrofuran-2-yl)methylidene]hydroxylamine
5-Nitrofurfural oxime
Nitrofuroxime
Mycofur
2-Furaldehyde, 5-nitro-, oxime, (Z)-
Micofur; Mycofur; NF 6; Nifuroxime; Nitrofuroxime
5-Nitrofurfuraldehyde oxime
Oprea1_628647
CHEMBL2362258
DTXSID50904488
CHEBI:134784
PTBKFATYSVLSSD-UHFFFAOYSA-N
5-Nitro-2-furaldehyde oxime, cis
AAA55515
AKOS030693155
NS00043305