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5-nitrofuran-2-carboxamide

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Identification
Molecular formula
C5H4N2O4
CAS number
4315-09-3
IUPAC name
5-nitrofuran-2-carboxamide
State
State

At room temperature, 5-nitrofuran-2-carboxamide exists in a solid state. It is not known to have any significant volatility.

Melting point (Celsius)
188.00
Melting point (Kelvin)
461.15
Boiling point (Celsius)
318.00
Boiling point (Kelvin)
591.15
General information
Molecular weight
156.10g/mol
Molar mass
156.1020g/mol
Density
1.5234g/cm3
Appearence

5-Nitrofuran-2-carboxamide typically appears as a crystalline solid that is yellow in color. The compound may exist as fine powder or small crystals depending on its preparation and purity.

Comment on solubility

Solubility of 5-nitrofuran-2-carboxamide

5-Nitrofuran-2-carboxamide, with its unique structure, exhibits a notable solubility profile. Here are some key points to consider:

  • Solvent Dependency: The solubility of 5-nitrofuran-2-carboxamide is largely influenced by the choice of solvent. It tends to be more soluble in polar solvents, such as water and methanol.
  • Temperature Effect: Increasing the temperature can enhance solubility. As temperature rises, molecular movements increase, often leading to a higher solvation rate.
  • pH Influence: The solubility can also be affected by the pH of the solution. As a weak acid, changes in pH can alter the ionization state of the compound, impacting its solubility.

To summarize, the solubility of 5-nitrofuran-2-carboxamide can be described as:

  1. Moderate in polar solvents
  2. Temperature-dependent, with increased solubility at higher temperatures
  3. pH-sensitive, displaying variable solubility based on the acidity or basicity of the solvent

As a result, those working with 5-nitrofuran-2-carboxamide should be aware of these factors to effectively utilize this compound in various applications.

Interesting facts

Interesting Facts about 5-nitrofuran-2-carboxamide

5-nitrofuran-2-carboxamide is an intriguing compound that plays an important role in various fields of chemistry and pharmaceutical research. Here are some notable aspects of this compound:

  • Pharmacological Potential: This compound possesses a range of biological activities. It has been studied for its potential as an antibacterial and antifungal agent. Its structure contributes to its effectiveness in disrupting microbial growth.
  • Chemical Versatility: The presence of both the nitro group and the carboxamide functional group allows for diverse reactivity, making it an excellent candidate for further chemical modifications. Researchers often explore these modifications to enhance its efficacy or to tailor its properties for specific applications.
  • Environmental Relevance: Compounds like 5-nitrofuran-2-carboxamide are essential in studying environmental pollutants. The nitrofuran derivatives are known for their stability, which can lead to their persistence in the environment, prompting research into their degradation pathways.

The study of 5-nitrofuran-2-carboxamide exemplifies how small changes in molecular structure can lead to significant differences in biological activity and environmental behavior. Its multifaceted roles in medicine and chemical synthesis continue to underscore the importance of this compound in contemporary research.

As you delve into the world of chemical compounds, remember the importance of compounds like 5-nitrofuran-2-carboxamide in advancing our understanding of both the biological landscape and the environmental implications of synthetic chemicals.

Synonyms
5-Nitro-2-furamide
2-FURAMIDE, 5-NITRO-
5-nitrofuran-2-carboxamide
2-Furancarboxamide, 5-nitro-
701-51-9
NSC-3185
5-Nitro-2-furoylamide
NSC 3185
AI3-17344
NSC3185
Maybridge1_006251
5-Nitro-2-furancarboxamide
Oprea1_794526
N874PQ8H2C
SCHEMBL1199803
HMS559E03
DTXSID90220376
CCG-1974
STK417236
AKOS003236212
DS-015504