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5-Nitro-2-furancarboxylic acid

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Identification
Molecular formula
C5H3NO5
CAS number
3615-01-0
IUPAC name
5-nitrofuran-2-carboxylic acid
State
State

At room temperature, 5-nitro-2-furancarboxylic acid is typically a solid state. It is not very volatile and maintains its form well under standard atmospheric conditions.

Melting point (Celsius)
197.00
Melting point (Kelvin)
470.00
Boiling point (Celsius)
326.00
Boiling point (Kelvin)
599.00
General information
Molecular weight
157.08g/mol
Molar mass
157.0840g/mol
Density
1.6410g/cm3
Appearence

5-Nitro-2-furancarboxylic acid typically appears as a yellow crystalline solid. It is characterized by its pale yellow color and crystalline texture.

Comment on solubility

Solubility of 5-nitrofuran-2-carboxylic acid

5-nitrofuran-2-carboxylic acid, with the chemical formula C5H4N2O4, exhibits interesting solubility characteristics that can be influenced by various factors. This compound is known to be:

  • Moderately soluble in water due to the presence of the carboxylic acid functional group, which can form hydrogen bonds with water molecules.
  • Soluble in polar organic solvents such as ethanol and methanol, which enhances its utility in organic synthesis.
  • Less soluble in non-polar solvents, reflecting its polar nature and the impact of the nitro group, which increases hydrogen bonding.

In terms of pH influence:

  • In acidic conditions, the carboxylic acid is likely to remain undissociated, which may limit solubility.
  • In alkaline conditions, deprotonation occurs, resulting in a more soluble anionic form.

This compound demonstrates the intricate balance of polarity, hydrogen bonding, and the effect of environmental conditions on solubility. As a result, understanding its solubility profile is crucial for applications in pharmaceuticals and materials science.

Interesting facts

Interesting Facts about 5-Nitrofuran-2-carboxylic Acid

5-Nitrofuran-2-carboxylic acid is a fascinating compound that holds significance across various scientific fields, particularly in organic chemistry and pharmaceuticals. Here are some of its notable aspects:

  • Chemical Structure: This compound features a furan ring, which is known for its five-membered ring structure with a nitrogen atom. The presence of the nitro group (–NO2) and carboxylic acid group (–COOH) plays a crucial role in its reactivity and potential applications.
  • Pharmaceutical Relevance: Due to its unique structure, 5-nitrofuran-2-carboxylic acid is studied for its antibacterial and antifungal properties. Its derivatives have shown *promise for developing new drugs* that combat infections.
  • Synthetic Versatility: Scientists appreciate this compound for its utility in synthetic organic chemistry. It serves as a valuable intermediate in the synthesis of various nitrogen-containing heterocycles, which are important in diverse chemical applications.
  • Environmental Considerations: The study of nitro-containing compounds, including 5-nitrofuran-2-carboxylic acid, often includes exploring their environmental impact. Research emphasizes understanding how such compounds degrade and their potential toxicity to ecosystems.
  • Research Opportunities: The ongoing exploration into this compound opens avenues for further research, including its biochemical interactions and potential uses in agriculture as a *biopesticide* or *herbicide*.

In summary, 5-nitrofuran-2-carboxylic acid is not just a compound with a structural formula; it encapsulates a range of potential applications and challenges, making it a subject of high interest for both researchers and students in the field of chemistry. As we continue to unravel its capabilities, the future may hold exciting developments stemming from this intriguing molecule.

Synonyms
5-NITRO-2-FUROIC ACID
5-Nitropyromucate
5-Nitrofurancarboxylic acid
CCRIS 1197
NSC 6452
EINECS 211-432-6
BRN 0139373
2-Furancarboxylic acid, 5-nitro
AI3-23599
DTXSID00214746
DTXCID30137237
2-Furancarboxylic acid, 5-nitro (9CI)
645-12-5
5-Nitrofuran-2-carboxylic acid
Nitrofurate
5-Nitrofuroic acid
5-Nitro-2-furancarboxylic Acid
2-Furoic acid, 5-nitro-
2-Furancarboxylic acid, 5-nitro-
MFCD00003240
5-Nitropyromucic acid
UTY7TN9FTP
NSC-6452
5-nitro2-furanoic acid
UNII-UTY7TN9FTP
2-Carboxy-5-nitrofuran
5-nitro-2-furanoic acid
CHEMBL1186
Oprea1_282165
5-NITRO-2-FUROICACID
SCHEMBL1221377
5-nitro-2-furan carboxylic acid
5-nitro-2-furan-carboxylic acid
5-Nitro-2-furoic acid, 98%
5-Nitro-furan-2-carboxylic acid
NSC6452
NITRO-2-FUROIC ACID, 5-
ALBB-031656
STR04789
STL164369
AKOS000119272
AKOS015894363
5-NITRO-2-FURYLCARBOXYLIC ACID
SY106223
DB-054680
N0557
NS00035709
EN300-17417
F16228
AE-641/02433026
Z56926611
F0001-1745