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5-Oxo-2-phenyl-tetrahydrofuran-3-carboxamide

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Identification
Molecular formula
C11H11NO3
CAS number
52198-48-0
IUPAC name
5-oxo-2-phenyl-tetrahydrofuran-3-carboxamide
State
State

Solid at room temperature.

Melting point (Celsius)
142.00
Melting point (Kelvin)
415.15
Boiling point (Celsius)
255.00
Boiling point (Kelvin)
528.15
General information
Molecular weight
205.22g/mol
Molar mass
205.2160g/mol
Density
1.3400g/cm3
Appearence

5-Oxo-2-phenyl-tetrahydrofuran-3-carboxamide is a white crystalline powder.

Comment on solubility

Solubility of 5-oxo-2-phenyl-tetrahydrofuran-3-carboxamide

The solubility of 5-oxo-2-phenyl-tetrahydrofuran-3-carboxamide in various solvents is an intriguing aspect of its chemical behavior. Generally, the solubility of a compound is influenced by several factors, including:

  • Molecular Structure: The presence of polar functional groups can enhance the solubility in polar solvents.
  • Temperature: Higher temperatures typically increase solubility for many compounds.
  • pH Levels: Altering the pH may affect the ionization of functional groups, which can in turn affect solubility.

In this specific case of 5-oxo-2-phenyl-tetrahydrofuran-3-carboxamide, observations indicate that:

  • It demonstrates moderate solubility in polar solvents such as water and methanol.
  • It shows limited solubility in non-polar solvents like hexane or benzene.

Understanding the solubility of this compound is essential for applications in synthesis and formulation, as it affects the methods of extraction, purification, and chemical reactions. As a general principle, the rule of thumb in solubility is: “like dissolves like,” suggesting that polar compounds tend to dissolve well in polar solvents, while non-polar compounds do not.

In summary, proper consideration of the solubility characteristics of 5-oxo-2-phenyl-tetrahydrofuran-3-carboxamide can significantly enhance its application potential in various chemical processes.

Interesting facts

Interesting Facts about 5-oxo-2-phenyl-tetrahydrofuran-3-carboxamide

5-oxo-2-phenyl-tetrahydrofuran-3-carboxamide is a compound that belongs to the class of heterocyclic organic compounds. Here are some fascinating insights into this unique molecule:

  • Diverse Applications: This compound shows potential applications in pharmaceuticals, particularly in drug development. Its structure could provide bases for new formulations targeting various health conditions.
  • Structural Significance: The presence of the tetrahydrofuran ring contributes significantly to the compound's chemical properties, influencing its interaction with biological systems and other chemicals.
  • Phenyl Group: The phenyl group attached to the structure contributes to its potential for pi-stacking interactions, which can be crucial in biological settings, such as protein-ligand bindings.
  • Research Interest: Scientists are increasingly exploring similar compounds because of their pharmacological activities, including anti-inflammatory and anticancer properties, inviting a plethora of research opportunities.
  • Analytical Chemistry: Techniques such as NMR (Nuclear Magnetic Resonance) and MS (Mass Spectrometry) are employed by chemists to delve deeper into understanding the behavior and characteristics of such compounds.

As scientists continue to unravel the mysteries of compounds like 5-oxo-2-phenyl-tetrahydrofuran-3-carboxamide, they open doors to innovative solutions in medicine and material sciences. The blend of structural complexity and potential utility makes this compound a noteworthy subject in chemical research!

Synonyms
5-Oxo-2-phenyltetrahydro-3-furamide
13390-01-7
3-FURAMIDE, TETRAHYDRO-5-OXO-2-PHENYL-
DTXSID00928331
5-Oxo-2-phenyloxolane-3-carboximidic acid