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L-Proline

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Identification
Molecular formula
C5H9NO2
CAS number
147-85-3
IUPAC name
5-oxopyrrolidine-2-carboxylic acid
State
State

At room temperature, L-Proline is a solid.

Melting point (Celsius)
220.00
Melting point (Kelvin)
493.15
Boiling point (Celsius)
257.00
Boiling point (Kelvin)
530.15
General information
Molecular weight
115.13g/mol
Molar mass
115.1300g/mol
Density
1.3500g/cm3
Appearence

L-Proline is a colorless to white crystalline powder.

Comment on solubility

Solubility of 5-oxopyrrolidine-2-carboxylic acid

The solubility of 5-oxopyrrolidine-2-carboxylic acid, with the chemical formula C5H9NO2, is an essential factor to consider in various applications. This compound exhibits several intriguing solubility characteristics:

  • Polar Nature: Due to the presence of the carboxylic acid group, 5-oxopyrrolidine-2-carboxylic acid displays a notable polar character, which typically enhances solubility in polar solvents.
  • Water Solubility: It is likely to be soluble in water due to its ability to form hydrogen bonds with water molecules, especially in acidic conditions.
  • Solvent Specificity: The solubility may vary depending on the pH of the solution and the presence of other solubilizing agents.
  • Applications: Its solubility properties are significant in fields such as pharmaceuticals and organic synthesis, where the solubility can affect bioavailability and reaction efficiency.

To sum up, **5-oxopyrrolidine-2-carboxylic acid** exhibits a solubility profile that is influenced by its molecular structure, including its polar functional groups. Understanding this solubility is crucial for harnessing its full potential in various chemical processes.

Interesting facts

Interesting Facts About 5-Oxopyrrolidine-2-carboxylic Acid

5-Oxopyrrolidine-2-carboxylic acid, often abbreviated as OPC, is a fascinating compound that occupies a unique position in organic chemistry due to its cyclic structure and functional groups. Here are some intriguing insights about this compound:

  • Cyclization: The compound features a five-membered ring structure, characteristic of pyrrolidine derivatives. This cyclic arrangement offers specific stability and reactivity patterns.
  • Biological Relevance: OPC is noteworthy for its presence in various biochemical processes. Its derivatives are studied for their potential roles in pharmaceutical applications, particularly in drug design and as building blocks in medicinal chemistry.
  • Relation to Other Compounds: This compound is closely related to proline, an amino acid that is crucial in the synthesis of proteins. The structural similarities suggest interesting metabolic pathways where OPC might play a role.
  • Potential Applications: Research indicates that compounds like OPC might show promise as intermediates in the synthesis of heterocyclic compounds, which are fundamental in developing new therapeutics.
  • Research Interest: The study of 5-oxopyrrolidine-2-carboxylic acid contributes to the broader field of heterocyclic chemistry, allowing scientists to explore the properties and reactions of nitrogen-containing rings.

As researchers continue to explore its properties and applications, OPC serves as an excellent example of how simple structural features can have significant implications in science and medicine.

Synonyms
DL-Pyroglutamic acid
149-87-1
5-Oxopyrrolidine-2-carboxylic acid
2-Pyrrolidone-5-carboxylic acid
5-Oxo-DL-proline
5-OXOPROLINE
DL-Proline, 5-oxo-
DL-2-Pyrrolidone-5-carboxylic acid
dl-pyrrolidonecarboxylic acid
6VT1YZM21H
DL-Glutamic Acid Lactam
MFCD00064322
NSC-40887
D-(+)-Pyroglutamic Acid
DL-2-Pyrrolidinone-5-carboxylic acid
OXOPROLINE
DL-Pidolic acid
5-Oxo-L-proline-d5
UNII-6VT1YZM21H
NSC143034
DL-5-Oxoproline
5-Oxoproline #
DL-Pyroglutamicacid
EINECS 205-748-3
NSC 40887
D,L-pyroglutamic acid
H-DL-Pyr-OH
(+/-)-pyroglutamic acid
PIDOLIC ACID, DL-
SCHEMBL15791
MLS001304098
PYROGLUTAMIC ACID, DL-
GTPL4703
CHEBI:16010
DTXCID50382626
DTXSID80859174
PROLINE, 5-OXO-, DL-
HMS2269D08
HMS3372F13
16891-48-8
ALBB-006003
GLP
NSC40887
5-oxo-pyrrolidine-2-carboxylic acid
BBL011576
STK290904
AKOS000119789
AKOS016338215
CS-W013454
FP39320
HY-W012738
PB42767
PS-6138
2-Pyrrolidone-5-carboxylic acid, 99%
(+/-)-2-pyrrolidone-5-carboxylic acid
NCGC00263467-03
SMR000112493
SY002490
DB-043022
DB-049588
DL-Pyroglutamic acid; DL-Pyroglutamic acid
G0061
NS00085313
EN300-19515
D77751
AB00443776-07
AG-205/32710031
SR-01000830710
SR-01000830710-3
Q27887010
F2190-0001
Z104474096
2027729E-091C-4F23-87AA-2D40D8A5C67C
205-748-3
5-Oxoproline; 5-Oxopyrrolidine-2-carboxylic acid; L-5-Pyrrolidone-2-carboxylic acid; (S)-(-)-2-Pyrrolidone-5-carboxylic acid