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5-Phenyl-1,2,3,4-tetrahydroisoquinoline

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Identification
Molecular formula
C15H15N
CAS number
19395-69-0
IUPAC name
5-phenyl-1,2,3,4-tetrahydroisoquinoline
State
State

At room temperature, 5-Phenyl-1,2,3,4-tetrahydroisoquinoline is typically in a solid state. Its molecular structure supports stability as a solid and contributes to its physical properties, making it useful in various chemical synthesis applications.

Melting point (Celsius)
110.00
Melting point (Kelvin)
383.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
209.27g/mol
Molar mass
209.2730g/mol
Density
1.1270g/cm3
Appearence

5-Phenyl-1,2,3,4-tetrahydroisoquinoline appears as a white to off-white solid. It may also be available in crystalline form, reflecting its aromatic and heterocyclic structure which contributes to its distinct appearance.

Comment on solubility

Solubility of 5-phenyl-1,2,3,4-tetrahydroisoquinoline

5-phenyl-1,2,3,4-tetrahydroisoquinoline is a complex organic compound that exhibits variable solubility in different solvents. Understanding its solubility is crucial for applications in various fields, particularly in pharmaceuticals and organic synthesis.

Key aspects of its solubility include:

  • Polar solvents: This compound tends to have limited solubility in polar solvents like water due to its hydrophobic aromatic ring structure.
  • Non-polar solvents: Solubility is generally greater in non-polar organic solvents such as hexane or chloroform, where the compound can effectively interact with solvent molecules.
  • Temperature dependence: The solubility profile may change with temperature; higher temperatures often increase solubility in organic solvents.
  • pH influence: As with many organic compounds, the solubility of 5-phenyl-1,2,3,4-tetrahydroisoquinoline may also be influenced by the pH of the solution, particularly in the presence of acidic or basic conditions.

In conclusion, while 5-phenyl-1,2,3,4-tetrahydroisoquinoline shows limited solubility in polar solvents, it demonstrates better solubility in non-polar environments and is affected by factors such as temperature and pH. Understanding these solubility characteristics is essential for optimizing its use in practical applications.

Interesting facts

Interesting Facts about 5-phenyl-1,2,3,4-tetrahydroisoquinoline

5-phenyl-1,2,3,4-tetrahydroisoquinoline is a fascinating compound within the world of organic chemistry, showcasing intriguing structural and functional characteristics. This compound is part of the isoquinoline family, which is essential in various biological processes and pharmaceutical applications. Here are some remarkable aspects about this compound:

  • Structural Diversity: The presence of a phenyl group gives rise to unique chemical properties and enhances interaction with biological systems.
  • Biological Relevance: Compounds structurally related to tetrahydroisoquinolines are known for their diverse pharmacological profiles, including anti-inflammatory and neuroprotective effects.
  • Synthesis Potential: The ability to synthesize 5-phenyl-1,2,3,4-tetrahydroisoquinoline through various methodologies, such as catalytic hydrogenation or cyclization reactions, makes it a subject of exploration for organic chemists.
  • Natural Occurrence: Some isoquinoline derivatives can be found in nature, especially in plants, which are often known for their medicinal uses. This raises interest in ethno-pharmacology.

As a student or scientist, it's crucial to appreciate how even a small modification in the molecular structure can lead to significant changes in the compound's properties and uses. The study of 5-phenyl-1,2,3,4-tetrahydroisoquinoline not only enhances our understanding of organic compounds but also encourages exploration in the field of synthetic chemistry and drug development.

In summary, the exploration of 5-phenyl-1,2,3,4-tetrahydroisoquinoline opens avenues for deeper insights into chemical behavior, synthesis techniques, and potential applications in medicine and pharmacology.

Synonyms
5-phenyl-1,2,3,4-tetrahydroisoquinoline
24464-38-8
SCHEMBL1403997
SCHEMBL29419338
AKOS013784388
DA-07746
EN300-1477318