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5-Phenyl-1,3,4-oxadiazol-2-amine

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Identification
Molecular formula
C8H7N3O
CAS number
5921-88-4
IUPAC name
5-phenyl-1,3,4-oxadiazol-2-amine
State
State

At room temperature, 5-Phenyl-1,3,4-oxadiazol-2-amine is typically found in a solid state. It is stable under standard laboratory conditions, and its crystalline form makes it suitable for various applications that involve organic synthesis.

Melting point (Celsius)
111.00
Melting point (Kelvin)
384.15
Boiling point (Celsius)
313.70
Boiling point (Kelvin)
586.85
General information
Molecular weight
175.19g/mol
Molar mass
175.1890g/mol
Density
1.3100g/cm3
Appearence

5-Phenyl-1,3,4-oxadiazol-2-amine appears as a solid crystalline powder that is typically white to pale yellow in color. It may also present a fine-grained texture depending on its level of purity and the processing method used during its synthesis or formulation.

Comment on solubility

Solubility of 5-phenyl-1,3,4-oxadiazol-2-amine

5-phenyl-1,3,4-oxadiazol-2-amine is an intriguing compound in regard to its solubility characteristics. Typically, the solubility of such organic compounds can be influenced by various factors including their molecular structure, the presence of polar groups, and interactions with solvents.

Key Points on Solubility:

  • Solvent Interaction: This compound is likely to exhibit moderate solubility in polar solvents like ethanol and dimethyl sulfoxide (DMSO) due to the presence of the amine group which can engage in hydrogen bonding.
  • Hydrophobic Effects: The phenyl group contributes to the lipophilicity of the molecule, which may decrease solubility in water and increase solubility in non-polar solvents.
  • Temperature Dependency: As with many organic compounds, solubility can increase with temperature, making higher temperatures potentially more favorable for dissolution.

It is important to note that solubility can be expressed quantitatively and can vary significantly depending on the conditions. In practical applications, the solubility of 5-phenyl-1,3,4-oxadiazol-2-amine should be determined experimentally to derive precise values, especially for its utility in pharmaceutical and materials applications.

Interesting facts

Interesting Facts about 5-Phenyl-1,3,4-oxadiazol-2-amine

5-Phenyl-1,3,4-oxadiazol-2-amine is a fascinating compound with a unique structure and several intriguing properties. As a member of the oxadiazole class, this compound has garnered attention in various scientific fields, particularly in medicinal chemistry and materials science.

Chemical Structure and Properties

  • Oxadiazole Framework: The presence of the oxadiazole ring contributes to the compound’s interesting electronic properties, making it a potential candidate for various applications.
  • Functional Groups: The amine group in 5-phenyl-1,3,4-oxadiazol-2-amine can engage in hydrogen bonding, enhancing its interaction with other molecules.
  • Phenyl Substituent: The phenyl group adds aromatic character to the molecule, which can influence its stability and reactivity.

Applications and Importance

  • Antimicrobial Activity: Compounds containing oxadiazole rings have shown promising antimicrobial properties, making them valuable in the development of new antibiotics.
  • Fluorescent Materials: Due to its unique structural features, this compound may be used in the design of fluorescent dyes or sensors.
  • Pharmaceutical Potential: The structure of 5-phenyl-1,3,4-oxadiazol-2-amine positions it as a potential precursor for the synthesis of drugs targeting various diseases.

As researchers delve deeper into the properties of 5-phenyl-1,3,4-oxadiazol-2-amine, they continue to discover new and exciting applications. This compound is not just a simple chemical entity; it represents the bridge between small molecules and their vast potential in innovative applications.

In the words of a prominent chemist, "Every compound tells a story, and understanding its narrative is key to unlocking its potential."

Synonyms
5-Phenyl-1,3,4-oxadiazol-2-amine
1612-76-6
2-Amino-5-phenyl-1,3,4-oxadiazole
1,3,4-OXADIAZOLE, 2-AMINO-5-PHENYL-
NSC 116132
DTXSID60167087
DTXCID9089578
626-851-3
cqsfycbgvmwpcm-uhfffaoysa-n
1,3,4-Oxadiazol-2-amine, 5-phenyl-
5-Phenyl-[1,3,4]oxadiazol-2-ylamine
5-Amino-2-phenyl-1,3,4-oxadiazole
2-Fenil-5-amino-1,3,4-ossadiazolo
MFCD00126383
2-Fenil-5-amino-1,3,4-ossadiazolo [Italian]
5-phenyl-1,3,4-oxadiazol-2-ylamine
5-phenyl-1,3,4-oxadiazole-2-ylamine
Cambridge id 5140657
SCHEMBL3979
TimTec1_001514
CHEMBL2426230
BDBM600903
HMS1538E18
ALBB-006413
NSC116132
STK500436
US11634391, Compound 137
1,4-Oxadiazol-2-amine, 5-phenyl-
1,4-Oxadiazole, 2-amino-5-phenyl-
AKOS000122056
CS-W004893
MB00695
NSC-116132
NCGC00174350-01
SY081589
2-Amino-5-phenyl-1,3,4-oxadiazole, 97%
A3074
EN300-02557
1,?3,?4-?Oxadiazol-?2-?amine, 5-?phenyl-
12L-713
A810242
AF-960/00445052
SR-01000401386
SR-01000401386-1
Z56788716
F0266-4159