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5-Phenyl-1,3,4-oxadiazole-2-thiol

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Identification
Molecular formula
C8H6N2OS
CAS number
3933-93-9
IUPAC name
5-phenyl-1,3,4-oxadiazole-2-thiol
State
State

At room temperature, 5-phenyl-1,3,4-oxadiazole-2-thiol is a solid. It is typically found in a crystalline form.

Melting point (Celsius)
212.00
Melting point (Kelvin)
485.15
Boiling point (Celsius)
342.00
Boiling point (Kelvin)
615.15
General information
Molecular weight
190.21g/mol
Molar mass
190.2140g/mol
Density
1.3500g/cm3
Appearence

5-Phenyl-1,3,4-oxadiazole-2-thiol typically appears as a yellow crystalline solid. It has a fine crystalline texture, and the color may vary slightly depending on the purity and specific sample conditions.

Comment on solubility

Solubility of 5-phenyl-1,3,4-oxadiazole-2-thiol

The solubility of 5-phenyl-1,3,4-oxadiazole-2-thiol can be described as follows:

  • Polar and Non-Polar Interactions: This compound contains both polar and non-polar functional groups, which suggests that its solubility will vary depending on the solvent used.
  • Aqueous Solubility: Generally, thiol compounds tend to have moderate solubility in water due to the presence of the -SH group, which can form hydrogen bonds with water molecules.
  • Solvent Compatibility: It is likely to be more soluble in organic solvents such as ethanol, methanol, and acetone due to its phenyl group enhancing hydrophobic interactions.
  • Temperature Dependence: The solubility can also be influenced by temperature; as the temperature increases, solubility usually improves for many organic compounds.

In summary, the solubility behavior of 5-phenyl-1,3,4-oxadiazole-2-thiol reflects its unique structural features, indicating potential for a broad range of applications in different solvent systems. Understanding these solubility characteristics is crucial for optimizing its use in chemical processes.

Interesting facts

Interesting Facts about 5-Phenyl-1,3,4-oxadiazole-2-thiol

5-Phenyl-1,3,4-oxadiazole-2-thiol is a fascinating compound that belongs to the class of oxadiazoles, which are recognized for their diverse applications in various fields of chemistry. Here are some intriguing aspects of this compound:

  • Structural Significance: The oxadiazole ring in this compound contributes to its unique properties and stability. It features a five-membered heterocyclic structure that incorporates nitrogen and sulfur, making it a valuable compound in pharmaceuticals and materials science.
  • Biological Activity: Several derivatives of oxadiazole compounds have been studied for their pharmaceutical potential. They can exhibit antimicrobial, antifungal, and anticancer activities, sparking interest among researchers for further exploration of 5-phenyl-1,3,4-oxadiazole-2-thiol in drug development.
  • Fluorescent Properties: Certain oxadiazole derivatives are known to possess fluorescence properties, which can be utilized in organic light-emitting diodes (OLEDs) and sensors. Investigating the photophysical characteristics of this compound could yield novel applications in optoelectronics.
  • Research Applications: The unique structure and reactivity of 5-phenyl-1,3,4-oxadiazole-2-thiol make it a target for research in organic synthesis and materials science. It is often explored for its potential role as a ligand in coordination chemistry.

In summary, 5-phenyl-1,3,4-oxadiazole-2-thiol is more than just a chemical compound; it is a bridge to various scientific explorations that may lead to significant advancements in pharmaceutical and materials research. As the field of chemistry continues to evolve, compounds like this one will undoubtedly play a crucial role in the discovery of new technologies and therapies.