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5-phenyl-1H-1,2,4-triazole-3-thiol

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Identification
Molecular formula
C9H7N3S
CAS number
32862-18-9
IUPAC name
5-phenyl-1H-1,2,4-triazole-3-thiol
State
State

At room temperature, 5-Phenyl-1H-1,2,4-triazole-3-thiol is in a solid state. It can exist as fine or coarse crystals depending on the conditions of storage and synthesis. The substance is stable under most conditions but should be stored away from moisture and light to prevent degradation.

Melting point (Celsius)
122.00
Melting point (Kelvin)
395.15
Boiling point (Celsius)
266.00
Boiling point (Kelvin)
539.00
General information
Molecular weight
191.22g/mol
Molar mass
191.2170g/mol
Density
1.3200g/cm3
Appearence

5-Phenyl-1H-1,2,4-triazole-3-thiol typically appears as a crystalline solid. The substance may vary in color from white to light yellow, influenced by the degree of purity and exact synthesis methods used. Crystals can vary in size depending on the crystallization conditions.

Comment on solubility

Solubility of 5-phenyl-1H-1,2,4-triazole-3-thiol

The solubility of 5-phenyl-1H-1,2,4-triazole-3-thiol is an intriguing characteristic that can affect its application in various fields, particularly in pharmaceuticals and agricultural chemistry. This compound displays some general trends in solubility:

  • Solvent Dependence: Its solubility can vary significantly depending on the solvent used. While it may dissolve well in polar solvents such as ethanol and dimethyl sulfoxide (DMSO), it typically shows limited solubility in non-polar solvents.
  • pH Influence: The solubility of the compound may also be influenced by the pH of the solution. Generally, changes in pH can impact the ionization state of the thiol group, leading to variations in solubility.
  • Temperature Effects: Increasing the temperature tends to enhance the solubility of solids. Thus, warming up the solvent could improve the dissolution of 5-phenyl-1H-1,2,4-triazole-3-thiol.

In summary, the solubility of 5-phenyl-1H-1,2,4-triazole-3-thiol is quite complex and is influenced by several factors. Researchers working with this compound should consider these variables to optimize its usage effectively.

Interesting facts

Interesting Facts about 5-phenyl-1H-1,2,4-triazole-3-thiol

5-phenyl-1H-1,2,4-triazole-3-thiol is a fascinating compound that falls within the category of triazoles, a class of five-membered heterocyclic rings containing three nitrogen atoms and two carbon atoms. This particular compound not only exhibits unique structural characteristics but also possesses several noteworthy properties:

  • Versatile Applications: This compound is widely researched for its utility in agriculture, particularly as a fungicide and herbicide. Its ability to inhibit various plant pathogens makes it significant in crop protection.
  • Pharmaceutical Potential: The presence of the triazole moiety is well-known in medicinal chemistry, contributing to numerous pharmaceutical agents. Its structural similarities to other bioactive compounds often lead to investigations targeting antimicrobial and anti-inflammatory effects.
  • Coordination Chemistry: 5-phenyl-1H-1,2,4-triazole-3-thiol is known to bind to metal ions, forming coordination complexes. This opens avenues for catalysis and materials science, especially in the synthesis of novel materials with tailored properties.
  • Research Interest: As a subject of extensive study, researchers are keen to explore its electronic properties and potential in organic electronics. The compound’s electron-density distribution presents intriguing opportunities for applications in sensors and conductive materials.

In terms of its impact on research, quotes from prominent scientists often highlight the triazole ring system's importance. As one chemist noted, "The ability of triazoles to stabilize various reactive intermediates has revolutionized how we synthesize complex organic molecules."
Such insights emphasize the broad implications of compounds like 5-phenyl-1H-1,2,4-triazole-3-thiol across multiple fields, making it a truly remarkable compound in both chemistry and industry.