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5-phenylpyrazole

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Identification
Molecular formula
C9H8N2
CAS number
13041-12-6
IUPAC name
5-phenyl-1H-pyrazole
State
State

At room temperature, 5-phenylpyrazole is typically found in a solid state. This compound, due to its aromatic structure, remains stable and retains its solid form under standard conditions.

Melting point (Celsius)
94.00
Melting point (Kelvin)
367.15
Boiling point (Celsius)
314.00
Boiling point (Kelvin)
587.15
General information
Molecular weight
144.17g/mol
Molar mass
144.1690g/mol
Density
1.1710g/cm3
Appearence

5-phenylpyrazole appears as a crystalline solid, often exhibiting a white or off-white color. Its precise appearance can vary slightly due to impurities or method of preparation, but it is generally found in solid form due to its high melting point.

Comment on solubility

Solubility of 5-phenyl-1H-pyrazole

5-phenyl-1H-pyrazole, a compound recognized for its aromatic structure, exhibits unique solubility characteristics. When discussing the solubility of this compound, it's essential to consider several factors:

  • Solvent Type: 5-phenyl-1H-pyrazole is primarily soluble in organic solvents such as methanol, ethanol, and dichloromethane.
  • Temperature Factors: Generally, an increase in temperature can enhance solubility, allowing for greater interaction with solvent molecules.
  • Polarity: Being less polar than water, 5-phenyl-1H-pyrazole shows minimal solubility in polar solvents, such as water.
  • Concentration: As with many organic compounds, a higher concentration of 5-phenyl-1H-pyrazole can lead to decreased solubility due to potential precipitation or saturation in solution.

As a result, it can be concluded that while 5-phenyl-1H-pyrazole is quite soluble in organic solvents, its solubility in aqueous environments is significantly limited. This behavior is not uncommon for many aromatic compounds, highlighting the role of chemical structure in determining solubility.

Interesting facts

Interesting Facts about 5-phenyl-1H-pyrazole

5-phenyl-1H-pyrazole is an intriguing compound that belongs to the pyrazole family of organic compounds, which are well-known for their diverse range of applications in both pharmaceuticals and agrochemicals. Here are some fascinating aspects of this compound:

  • Pharmaceutical Relevance: 5-phenyl-1H-pyrazole derivatives have been studied for their potential anti-inflammatory, analgesic, and antimicrobial properties, making them valuable in drug development.
  • Agrochemical Applications: This compound's structure lends itself to use in developing herbicides and pesticides, where it may aid in pest control strategies in agriculture.
  • Diverse Chemistry: The pyrazole ring, which features prominently in this compound, is known for its ability to engage in various chemical reactions, facilitating the synthesis of complex molecular architectures.
  • Biological Activity: Certain derivatives of 5-phenyl-1H-pyrazole have shown promising results in inhibiting specific enzymes, which may contribute to their therapeutic effectiveness.

As a scientist, it is enthralling to analyze how a small modification in the molecular structure can lead to significantly different biological activities and functionalities. The exploration of compounds like 5-phenyl-1H-pyrazole not only furthers our understanding of organic chemistry but also enhances our capability to create novel solutions in medicine and agriculture.

Quotes from researchers often highlight the importance of such compounds: "In the world of chemistry, small changes can lead to groundbreaking discoveries." Such statements truly capture the essence of molecular exploration.

Thus, 5-phenyl-1H-pyrazole serves as a perfect example of how a seemingly simple compound can turn into a critical component of advanced scientific research.

Synonyms
2458-26-6
3-Phenylpyrazole
1H-Pyrazole, 3-phenyl-
PYRAZOLE, 3-PHENYL-
DTXSID40179320
DTXCID70101811
oeduifsdodudrk-uhfffaoysa-n
3-Phenyl-1H-pyrazole
5-phenyl-1H-pyrazole
phenylpyrazole
MFCD00159654
CHEMBL38876
5-phenylpyrazole
3-Phenyl pyrazole
3-Phenyl-1H-pyrazole #
pyrazole, 3(5)-phenyl-
SCHEMBL9438
3-Phenyl-1H-pyrazole, 97%
ALBB-005415
BCP25611
BDBM50078831
CL3440
STK097634
AKOS000313117
AKOS000345348
AS-5622
CS-W002461
HY-W002461
NCGC00331164-01
AC-23138
SY009071
DB-011228
P2063
EN300-62492
AB01205810-03
Q63398285
F1667-0020
Z1224534135