5-phenyl-3-(2-pyrrolidin-1-ylethyl)isoxazole

Identification

Molecular formula

C₁₅H₁₈N₂O

CAS number

672948-87-3

IUPAC name

5-phenyl-3-(2-pyrrolidin-1-ylethyl)isoxazole

State

At room temperature, this compound is a solid, usually appearing in powder form.

Melting point (Celsius)

134.00

Melting point (Kelvin)

407.15

Boiling point (Celsius)

356.00

Boiling point (Kelvin)

629.15

General information

Molecular weight

252.32g/mol

Molar mass

252.3170g/mol

Density

1.2000g/cm³

Appearence

The compound is typically a solid, often appearing as a powder or crystalline substance.

Comment on solubility

Solubility of 5-phenyl-3-(2-pyrrolidin-1-ylethyl)isoxazole

The solubility of 5-phenyl-3-(2-pyrrolidin-1-ylethyl)isoxazole in various solvents can be complex due to its unique chemical structure. This compound exhibits key characteristics that influence its solubility:

Polar vs Non-Polar Solvents: It is essential to consider that compounds containing both polar and non-polar functional groups often show different solubility behaviors. For example, 5-phenyl-3-(2-pyrrolidin-1-ylethyl)isoxazole may be more soluble in polar solvents such as water or alcohols, compared to non-polar solvents like hexane.
Temperature Dependency: As is common with many organic compounds, the solubility can increase with temperature. Thus, you may find that 5-phenyl-3-(2-pyrrolidin-1-ylethyl)isoxazole dissolves better at elevated temperatures.
pH Sensitivity: The solubility might also be affected by the pH of the solution. Compounds with basic or acidic groups can show varying solubility depending on the surrounding pH.

In summary, the solubility of 5-phenyl-3-(2-pyrrolidin-1-ylethyl)isoxazole is significantly influenced by its polarity, the type of solvent used, temperature, and the pH level. To fully assess its solubility profile, empirical results from testing in various solvents at different temperatures are recommended.

Interesting facts

Interesting Facts about 5-Phenyl-3-(2-Pyrrolidin-1-ylethyl)Isoxazole

5-Phenyl-3-(2-pyrrolidin-1-ylethyl)isoxazole is a fascinating compound that belongs to the class of isoxazoles, which are five-membered aromatic heterocyclic compounds that contain both an oxygen and nitrogen atom in the ring. Here are some intriguing insights about this compound:

Versatile Structure: The unique structure of 5-phenyl-3-(2-pyrrolidin-1-ylethyl)isoxazole combines a phenyl ring with a pyrrolidine part, enhancing its biological activity and making it an important candidate for medicinal chemistry.
Biological Significance: Compounds in the isoxazole class have shown a range of biological activities such as antiepileptic, analgesic, and anti-inflammatory properties. This makes 5-phenyl-3-(2-pyrrolidin-1-ylethyl)isoxazole a potential target for drug development.
Research Potential: Researchers are particularly interested in derivatives of this compound as they may exhibit selective activity towards various receptor sites, aiding in the development of more effective therapies.
Synthetic Pathways: The synthesis of isoxazoles typically involves the reaction of substituted hydroxylamines with various carbonyl compounds, showcasing the richness of organic synthesis techniques necessary to create such compounds.
Interdisciplinary Applications: Beyond medicinal uses, compounds containing the isoxazole framework have applications in fields such as materials science, agricultural chemistry, and as ligands in coordination chemistry.

As a part of ongoing research, the full range of its biological effects and potential therapeutic applications continues to be a subject of interest. Challenging and exciting, the study of 5-phenyl-3-(2-pyrrolidin-1-ylethyl)isoxazole not only contributes to our understanding of organic chemistry but also opens doors to innovative solutions in drug discovery.