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5-Phenyl-3-(pyrrolidin-1-ium-1-ylmethyl)isoxazole chloride

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Identification
Molecular formula
C14H17ClN2O
CAS number
1257836-85-4
IUPAC name
5-phenyl-3-(pyrrolidin-1-ium-1-ylmethyl)isoxazole;chloride
State
State
At room temperature, this compound is in the solid state. It is typically found in a crystalline or powder form.
Melting point (Celsius)
210.00
Melting point (Kelvin)
483.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
-273.15
General information
Molecular weight
262.74g/mol
Molar mass
262.7400g/mol
Density
1.2524g/cm3
Appearence

This compound typically appears as a white to off-white solid powder or crystalline substance. The precise appearance can vary slightly depending on the form it is in and the method of preparation.

Comment on solubility

Solubility of 5-phenyl-3-(pyrrolidin-1-ium-1-ylmethyl)isoxazole; chloride

The solubility of 5-phenyl-3-(pyrrolidin-1-ium-1-ylmethyl)isoxazole; chloride is a noteworthy aspect of its chemical characteristics, especially considering its structural features. Being a quaternary ammonium compound, it displays some distinct trends regarding its solubility:

  • Polarity: The presence of the pyrrolidin-1-ium ion typically increases the compound's polarity, enhancing its solubility in polar solvents such as water and alcohols.
  • Ionic Strength: As a chloride salt, the ionic nature of the compound may enable it to dissolve well in aqueous solutions, where chloride ions can interact favorably with water molecules.
  • Hydrogen Bonding: The isoxazole ring might participate in hydrogen bonding, which can further influence its solubility in various solvents.
  • Temperature Dependency: It is anticipated that the solubility may increase with temperature, a common phenomenon for many organic salts.

It's important to note that while water solubility is likely significant, organic solvents could also provide an alternative medium for dissolution. However, empirical testing would be essential to ascertain specific solubility values under varying conditions.

In conclusion, understanding the solubility behavior of this compound can provide valuable insights for potential applications in chemistry and pharmaceuticals, as solubility often governs the bioavailability and efficacy of drug compounds.

Interesting facts

Interesting Facts about 5-Phenyl-3-(pyrrolidin-1-ium-1-ylmethyl)isoxazole; Chloride

5-Phenyl-3-(pyrrolidin-1-ium-1-ylmethyl)isoxazole; chloride is an intriguing compound that garners attention in various fields of chemistry, particularly in medicinal chemistry and materials science. Here are some notable aspects:

  • Structure and Function: This compound features a unique isoxazole ring, which plays a crucial role in its biological activity. The presence of a phenyl group and the pyrrolidin-1-ium substituent enhances its potential as a pharmacophore, potentially influencing interactions with biological targets.
  • Medicinal Potential: Compounds containing isoxazole moieties have been identified as promising candidates for the development of pharmaceuticals, notably in the treatment of neurodegenerative diseases. Their ability to modulate various biological pathways makes them a subject of ongoing research.
  • Chloride Role: The chloride ion associated with this compound can serve as a stabilizing counterion, impacting solubility and bioavailability. Understanding its role is crucial for formulation chemistry.
  • Synthesis Insights: The synthesis of this compound may involve innovative synthetic routes that leverage modern organic chemistry techniques, such as nucleophilic substitutions and cyclization reactions. This ability to create complex structures elegantly exemplifies contemporary synthetic chemistry.
  • Potential Applications: Beyond medicinal uses, compounds like this one have potential applications in materials science, particularly in designing functional materials for electronics, sensors, or as catalysts in organic reactions.

As researchers continue to delve into the properties and applications of 5-phenyl-3-(pyrrolidin-1-ium-1-ylmethyl)isoxazole; chloride, it stands as a reminder of the fascinating complexity and promise that chemical compounds hold in the pursuit of innovation.

"Understanding the chemistry of a compound goes beyond its formula; it's about exploring its potential to change lives."

Synonyms
Isoxazole, 5-phenyl-3-(pyrrolidinomethyl)-, hydrochloride
1215-25-4
3-(Pyrrolidinomethyl)-5-phenylisoxazole hydrochloride
ISOXAZOLE, 5-PHENYL-3-(1-PYRROLIDINYLMETHYL)-, HYDROCHLORIDE
5-Phenyl-3-(pyrrolidin-1-ylmethyl)isoxazolehydrochloride
5-phenyl-3-(pyrrolidin-1-ium-1-ylmethyl)-1,2-oxazole;chloride