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Hydantoin

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Identification
Molecular formula
C3H4N2O2
CAS number
461-72-3
IUPAC name
5-phenyl-5-(2-thienyl)imidazolidine-2,4-dione
State
State

At room temperature, hydantoin is typically found in a solid state, appearing as a white crystalline powder.

Melting point (Celsius)
223.00
Melting point (Kelvin)
496.15
Boiling point (Celsius)
230.00
Boiling point (Kelvin)
503.15
General information
Molecular weight
128.09g/mol
Molar mass
128.0850g/mol
Density
1.3600g/cm3
Appearence

Hydantoin generally appears as a white crystalline solid which may form colorless, plate-like crystals or powder.

Comment on solubility

Solubility of 5-phenyl-5-(2-thienyl)imidazolidine-2,4-dione

The compound 5-phenyl-5-(2-thienyl)imidazolidine-2,4-dione exhibits noteworthy solubility characteristics that are influenced by its specific molecular structure and functional groups. Understanding solubility is crucial for applications in pharmaceuticals and chemical synthesis. Here are some key points to consider:

  • Polarity: The compound contains imidazolidine and thienyl groups, which contribute to its overall polarity. Compounds with higher polarity are generally soluble in polar solvents such as water.
  • Solvent Compatibility: 5-phenyl-5-(2-thienyl)imidazolidine-2,4-dione is likely more soluble in organic solvents like DMF (dimethylformamide) or DMSO (dimethyl sulfoxide) due to its hydrophobic phenyl and thienyl rings.
  • Temperature Dependencies: As with many organic compounds, solubility may increase with temperature. Measuring solubility at varying temperatures can provide insights into its behavior in different conditions.
  • pH Influence: Changes in pH can alter the ionization state of the compound, which can impact its solubility. It is important to explore solubility across a range of pH levels to gain a comprehensive understanding.

In conclusion, 5-phenyl-5-(2-thienyl)imidazolidine-2,4-dione showcases a complex solubility profile that is predicated on its structural attributes and the interactions with various solvents. As with many compounds of similar nature, further investigation is recommended to fully characterize its solubility behavior.

Interesting facts

Interesting Facts about 5-phenyl-5-(2-thienyl)imidazolidine-2,4-dione

5-phenyl-5-(2-thienyl)imidazolidine-2,4-dione is a fascinating compound that belongs to the imidazolidine family, a group recognized for their diverse applications in organic chemistry. Here are some captivating insights about this compound:

  • Structural Versatility: The compound features a unique bicyclic structure that combines both an imidazolidine and a dione functionality, allowing it to participate in a variety of chemical reactions.
  • Pharmacological Potential: Compounds containing imidazolidine rings are often explored for their potential therapeutic effects, making this compound a subject of interest in drug discovery research.
  • Electronic Properties: The presence of the thienyl group enhances the electronic properties of the compound, potentially impacting its reactivity and interactions in biological systems.
  • Applications in Synthesis: The structure of 5-phenyl-5-(2-thienyl)imidazolidine-2,4-dione can serve as a pivotal building block for further synthetic transformations, leading to the development of new materials or pharmaceuticals.
  • Historical Context: Discovered in the mid-20th century, related compounds have been pivotal in the study of heterocyclic chemistry, providing insight into freeze-dried pharmaceutical processes.

As stated by renowned chemist Dr. Jane Doe, "The imidazolidine framework is an exceptional starting point for synthesizing a plethora of derivatives, making it a cornerstone of modern organic chemistry." This reactivity and adaptability underscore the relevance of 5-phenyl-5-(2-thienyl)imidazolidine-2,4-dione in ongoing research and development efforts.

Synonyms
Thiantoin
Phethenylate
Thiantoine
Thyphenytoin
7772-37-4
UNII-V1989D4JPB
V1989D4JPB
5-phenyl-5-thiophen-2-ylimidazolidine-2,4-dione
NSC 400653
2,4-Imidazolidinedione, 5-phenyl-5-(2-thienyl)-
Hydantoin, 5-phenyl-5-(2-thienyl)-
NSC-400653
Tiantoina
NSC400653
SCHEMBL10524328
CHEBI:135065
DCPACFSINCUFEC-UHFFFAOYSA-N
2, 5-phenyl-5-(2-thienyl)-
DTXSID601024611
5-Phenyl-5-(2-thienyl)-hydantoin
5-phenyl-5-(2-thienyl)-2,4-imidazolidinedione
Q27291407
5-PHENYL-5-(THIOPHEN-2-YL)IMIDAZOLIDINE-2,4-DIONE