Interesting facts
Interesting Facts about 5-Phenyl-7-(Trifluoromethyl)-1,3-Dihydro-1,4-benzodiazepin-2-one
This compound belongs to the benzodiazepine class, which is widely recognized for its therapeutic effects. Here are some key points to highlight:
- Pharmacological Significance: Benzodiazepines like this compound are primarily known for their roles as anxiolytics and sedatives. They act on the central nervous system and are often used to manage anxiety disorders, insomnia, and seizure disorders.
- Structure-Activity Relationship: The unique substitution at position 7 with a trifluoromethyl group can significantly enhance the compound's potency and pharmacokinetic properties. Understanding such modifications is crucial for medicinal chemists seeking to optimize drug performance.
- Potential Research Areas: Due to its distinctive chemical structure, this compound could be a subject of intense research for developing new drugs. Investigating how the trifluoromethyl group interacts with biological targets might reveal novel mechanisms of action.
- Drug Development: Conducting studies involving this compound could lead to the discovery of safer and more effective benzodiazepine derivatives, paving the way for innovation in anxiety treatment.
- Cultural Impact: Benzodiazepines have garnered considerable attention in discussions surrounding mental health. As researchers explore their effects, compounds like this one may contribute to redefining treatment strategies or public perceptions about anxiety relief.
The exploration of 5-phenyl-7-(trifluoromethyl)-1,3-dihydro-1,4-benzodiazepin-2-one not only contributes to basic scientific knowledge but also holds promise for improving patient care through targeted medicinal chemistry.
Synonyms
2285-16-7
Triflunordazepam
2H-1,4-BENZODIAZEPIN-2-ONE, 1,3-DIHYDRO-5-PHENYL-7-(TRIFLUOROMETHYL)-
Ro5-2904
5-phenyl-7-(trifluoromethyl)-1,3-dihydro-1,4-benzodiazepin-2-one
8CS486VL3D
RO-052904
Ro 5-2904
BRN 0758865
1,3-Dihydro-5-phenyl-7-trifluoromethyl-2H-1,4-benzodiazepin-2-one
UNII-8CS486VL3D
5-24-04-00415 (Beilstein Handbook Reference)
CHEMBL13039
SCHEMBL7322754
DTXSID70177394
UUBMOUNXQFMBQF-UHFFFAOYSA-N
BDBM50408024
Ro-05-2904
Q7339204
1,3-Dihydro-5-phenyl-7-(trifluoromethyl)-2H-1,4-benzodiazepin-2-one
Solubility of 5-phenyl-7-(trifluoromethyl)-1,3-dihydro-1,4-benzodiazepin-2-one
The solubility of 5-phenyl-7-(trifluoromethyl)-1,3-dihydro-1,4-benzodiazepin-2-one presents an intriguing case due to its unique chemical structure and the presence of specific functional groups. When exploring its solubility, several factors come into play:
However, due to the specific structural features, empirical solubility data is crucial for determining suitable solvents. It's often observed that substituents like trifluoromethyl can lead to significantly altered solubility properties compared to non-fluorinated analogs.
As a closing thought, solubility can be a complex interplay of various molecular attributes, and understanding these can aid in predicting the behavior of 5-phenyl-7-(trifluoromethyl)-1,3-dihydro-1,4-benzodiazepin-2-one in different chemical contexts.