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5-(prop-2-ynoxymethyl)tetrahydrofuran-2-one

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Identification
Molecular formula
C8H10O3
CAS number
4201-38-3
IUPAC name
5-(prop-2-ynoxymethyl)tetrahydrofuran-2-one
State
State

At room temperature, 5-(prop-2-ynoxymethyl)tetrahydrofuran-2-one is typically in a liquid state. It is a relatively stable compound under standard laboratory conditions.

Melting point (Celsius)
-50.00
Melting point (Kelvin)
223.15
Boiling point (Celsius)
172.00
Boiling point (Kelvin)
445.15
General information
Molecular weight
126.14g/mol
Molar mass
126.1420g/mol
Density
1.1250g/cm3
Appearence

5-(Prop-2-ynoxymethyl)tetrahydrofuran-2-one typically appears as a colorless to pale yellow liquid. It has a distinct molecular structure featuring a furanone ring bound to an alkynyl ether group, which can impart a mild aromatic scent characteristic of many lactones.

Comment on solubility

Solubility of 5-(prop-2-ynoxymethyl)tetrahydrofuran-2-one

The solubility of 5-(prop-2-ynoxymethyl)tetrahydrofuran-2-one can be influenced by several factors. Understanding these aspects can provide insights into how this compound behaves in different environments:

  • Polarity: The presence of functional groups in the compound affects its polarity. Generally, polar compounds are soluble in polar solvents, while non-polar compounds dissolve in non-polar solvents.
  • Hydrogen Bonding: Compounds that can engage in hydrogen bonding typically exhibit higher solubility in water, which is a polar solvent rich in hydrogen bond formation. This compound's ability to form such interactions can enhance its solubility.
  • Temperature: As with many organic compounds, increasing the temperature can boost solubility. It enables more significant interactions with solvents, thus enhancing the solute's dispersion.
  • Structural Factors: The cyclic structure, combined with the substituents, can create steric hindrances or facilitate solubility. The unique structure of this compound may necessitate specific conditions for adequate solubility.

It is important to note that empirical studies and experimentation are essential for obtaining precise solubility data for 5-(prop-2-ynoxymethyl)tetrahydrofuran-2-one. As stated, "Solubility is a nuanced characteristic that cannot be predicted solely by formula." Factors like solvent choice, temperature, and structural features must all be considered to grasp the full picture of this compound's solubility.

Interesting facts

Interesting Facts about 5-(prop-2-ynoxymethyl)tetrahydrofuran-2-one

5-(prop-2-ynoxymethyl)tetrahydrofuran-2-one is a fascinating chemical compound with several noteworthy attributes that make it a subject of interest in organic chemistry.

Key Attributes

  • Structural Complexity: This compound features a unique bicyclic structure that incorporates a furan ring. Such structures are essential in medicinal chemistry, often demonstrating interesting biological activity.
  • Functional Group Diversity: The presence of a propargyl ether moiety introduces multiple reactive sites, allowing for extensive modifications. This functionality can be exploited in synthetic chemistry to develop a range of derivatives.
  • Significance in Synthesis: The tetrahydrofuran scaffold is prevalent in various natural products and pharmacologically active compounds, making 5-(prop-2-ynoxymethyl)tetrahydrofuran-2-one a potentially valuable intermediate for synthetic routes in drug design.
  • Potential Applications: Due to its structural features, this compound could be explored for applications in polymer science or as a building block for more complex organic molecules.

Conclusion

In summary, 5-(prop-2-ynoxymethyl)tetrahydrofuran-2-one stands out for its structural complexity and potential applications in both synthetic and medicinal chemistry. Its rich tapestry of functional groups can lead to the generation of a library of derivatives, each offering unique properties and uses. As with many compounds in organic synthesis, continued research is likely to unveil even more valuable insights and applications.

Synonyms
BRN 1636770
Dihydro-5-(2-propynyloxymethyl)-2(3H)-furanone
Propargyloxymethyl-4 gamma-butyrolactone
27850-25-5
gamma-Butyrolactone, 4-(2-propynyloxymethyl)-
2(3H)-FURANONE, DIHYDRO-5-(2-PROPYNYLOXYMETHYL)-
RefChem:241662
DTXSID70950523
5-{[(Prop-2-yn-1-yl)oxy]methyl}oxolan-2-one