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5-tert-butyl-7-methyl-[1,3]dioxolo[4,5-g]isoquinoline

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Identification
Molecular formula
C15H17NO2
CAS number
112750-58-2
IUPAC name
5-tert-butyl-7-methyl-[1,3]dioxolo[4,5-g]isoquinoline
State
State

At room temperature, 5-tert-butyl-7-methyl-[1,3]dioxolo[4,5-g]isoquinoline is in a solid state. It is typically stored in a dry environment to maintain its stability and prevent any degradation that could result from exposure to moisture.

Melting point (Celsius)
152.00
Melting point (Kelvin)
425.00
Boiling point (Celsius)
290.00
Boiling point (Kelvin)
563.00
General information
Molecular weight
241.30g/mol
Molar mass
241.2980g/mol
Density
1.0500g/cm3
Appearence

5-tert-butyl-7-methyl-[1,3]dioxolo[4,5-g]isoquinoline appears as a crystalline solid with a light brownish color. The compound may exhibit a shiny or opaque surface, depending on the purity and form of the material.

Comment on solubility

Solubility of 5-tert-butyl-7-methyl-[1,3]dioxolo[4,5-g]isoquinoline

The solubility of 5-tert-butyl-7-methyl-[1,3]dioxolo[4,5-g]isoquinoline can be quite intriguing due to its unique structural characteristics. Several factors influence the solubility of this compound:

  • Polarity: The presence of functional groups that can engage in hydrogen bonding or dipole interactions may enhance or hinder solubility in certain solvents.
  • Solvent Interaction: This compound may display differential solubility in polar vs. non-polar solvents, often being more soluble in organic solvents such as dichloromethane or ethanol.
  • Temperature: Increasing temperature can significantly affect solubility; for many compounds, solubility increases at elevated temperatures.
  • Crystallinity: A high degree of crystallinity can lead to lower solubility; thus, understanding the solid-state properties is crucial.

It is often observed that compounds with complex rings and substitutions, like 5-tert-butyl-7-methyl-[1,3]dioxolo[4,5-g]isoquinoline, exhibit limited solubility in aqueous solutions but may dissolve well in various organic solvents. This behavior highlights the need for careful consideration of the solvent system when conducting experiments or applications involving this compound. It is essential to remember that “solubility is not just about what dissolves, but how well it interacts with the solvent,” which can lead to variations in solubility profiles.


Interesting facts

Interesting Facts about 5-tert-butyl-7-methyl-[1,3]dioxolo[4,5-g]isoquinoline

This fascinating compound, 5-tert-butyl-7-methyl-[1,3]dioxolo[4,5-g]isoquinoline, belongs to the isoquinoline family of alkaloids, which are known for their diverse biological activities. Isoquinolines have long been of interest in medicinal chemistry due to their potential therapeutic properties.

Biological Significance

  • Antimicrobial Properties: Isoquinoline derivatives are often studied for their ability to combat various pathogens, making them valuable candidates for antibiotic development.
  • Anti-Cancer Potential: Certain compounds in the isoquinoline family have shown promise in inhibiting the proliferation of cancer cells, contributing to ongoing research in oncology.
  • Neurological Research: Some studies suggest isoquinoline compounds may have neuroprotective effects, which could provide insights into treatments for neurodegenerative diseases.

Chemical Structure

The unique structure of 5-tert-butyl-7-methyl-[1,3]dioxolo[4,5-g]isoquinoline contributes to its interesting properties:

  • Dioxole Ring System: The presence of a dioxole ring enhances molecular stability and can affect interactions with biological receptors.
  • Substituents: The tert-butyl and methyl groups introduce steric factors that can influence solubility and reactivity, crucial for drug design.

Applications in Research

This compound's intriguing molecular architecture points to a range of applications:

  • It serves as a template for synthesizing new pharmaceutical agents.
  • Investigating its reactivity leads to a better understanding of complex reactions in organic chemistry.
  • It provides insights into structure-activity relationships in drug discovery.

In conclusion, 5-tert-butyl-7-methyl-[1,3]dioxolo[4,5-g]isoquinoline exemplifies the captivating intersection of organic chemistry and medicinal research. The ongoing exploration of isoquinoline derivatives promises to yield new compounds that may significantly impact healthcare and drug development.