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Barbital

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Identification
Molecular formula
C12H16N2O3
CAS number
57-44-3
IUPAC name
5,5-dibenzylhexahydropyrimidine-2,4,6-trione
State
State

At room temperature, barbital is a solid. Its stable crystalline form ensures that it remains in this state under normal conditions, contributing to its widespread use and handling in laboratories and industrial applications.

Melting point (Celsius)
190.50
Melting point (Kelvin)
463.65
Boiling point (Celsius)
232.50
Boiling point (Kelvin)
505.65
General information
Molecular weight
238.27g/mol
Molar mass
238.2730g/mol
Density
1.2409g/cm3
Appearence

Barbital typically appears as a white, crystalline powder. It is known for its purity and crystalline nature which lends it a distinct look amongst other similar compounds. Its solid structure and colorless nature make it easily identifiable when in its pure form.

Comment on solubility

Solubility of 5,5-Dibenzylhexahydropyrimidine-2,4,6-trione

The solubility of 5,5-dibenzylhexahydropyrimidine-2,4,6-trione can be quite fascinating, given its organic nature and intricate structure. This compound is characterized by its unique trione functionality, which can influence its interactions with solvents. Here are some key points to consider:

  • Polar vs. Non-Polar Solvents: The solubility of this compound is largely dependent on the polarity of the solvent used. Polar solvents such as water may not dissolve it well, whereas non-polar solvents like hexane can demonstrate better solubility.
  • Hydrogen Bonding: The presence of the trione group can lead to the potential for hydrogen bonding with appropriate solvents, which can enhance solubility in certain polar environments.
  • Clinical Relevance: Understanding its solubility is crucial in pharmaceutical applications, as it may affect the drug's bioavailability and efficacy.

In summary, the solvent system plays a decisive role in the solubility behavior of 5,5-dibenzylhexahydropyrimidine-2,4,6-trione, highlighting the importance of selecting the correct medium for desired applications. Consequently, further experimental studies are advised to chart its solubility profile more accurately.

Interesting facts

Exploring 5,5-Dibenzylhexahydropyrimidine-2,4,6-trione

5,5-Dibenzylhexahydropyrimidine-2,4,6-trione is a fascinating compound with a wealth of interesting characteristics that pique the curiosity of chemists and researchers alike. Below are some notable facts that highlight its significance:

  • Cyclic Structure: This compound features a unique hexahydropyrimidine ring, which is indicative of its cyclic nature, providing it with distinctive chemical properties.
  • Diverse Applications: Compounds like 5,5-dibenzylhexahydropyrimidine-2,4,6-trione are often explored in the field of medicinal chemistry. Their structural complexity can lead to potential applications in pharmaceuticals or as intermediates in organic synthesis.
  • Interactions and Reactivity: The presence of multiple carbonyl groups (the 'trione' part) lends itself to interesting reactivities, including potential hydrogen bonding and electrophilicity, which can be utilized in various chemical reactions.
  • Historical Context: Pyrimidine derivatives have been studied extensively since the early 20th century and have made their mark in the development of antimetabolic drugs, showcasing the relevance of compounds like this in modern chemistry.
  • Research Potential: Given its structure, this compound may serve as a template for the design of new molecules with enhanced biological activity, making it an exciting subject for ongoing research.

In summary, 5,5-dibenzylhexahydropyrimidine-2,4,6-trione is not merely a chemical entity; it symbolizes the intersection of science and creativity in chemical synthesis. Exploring its properties may unlock new avenues for research and application, making it a compound worthy of attention.

Synonyms
BARBITURIC ACID, 5,5-DIBENZYL-
26371-47-1
5,5-Dibenzyl-barbituric acid
D573F0T1Z0
NSC-109107
DTXSID00180972
RefChem:1072125
DTXCID40103463
5,5-Dibenzylbarbituric acid
MLS002704121
NSC 109107
BRN 0284477
Dibenzylbarbitursaure
NSC109107
Barbituric acid,5-dibenzyl-
Oprea1_336969
5-24-09-00362 (Beilstein Handbook Reference)
UNII-D573F0T1Z0
SCHEMBL5448618
CHEMBL1893236
MFCD00596755
AKOS001587362
CCG-103770
SMR001570827
DS-003572
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5,5-bis(phenylmethyl)-
2,4,6(1H,3H,5H)-PYRIMIDINETRIONE,5,5-BIS(PHENYLMETHYL)-
5,5-BIS(PHENYLMETHYL)-2,4,6(1H,3H,5H)-PYRIMIDINETRIONE