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Droperidol

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Identification
Molecular formula
C25H27NO4
CAS number
548-73-2
IUPAC name
5,5-diphenyl-2-[2-(1-piperidyl)ethyl]-1,3-dioxolan-4-one;hydrochloride
State
State

At room temperature, droperidol hydrochloride typically exists in a solid state. It remains stable under normal atmospheric conditions and does not evaporate or sublimate at standard room temperature and pressure.

Melting point (Celsius)
110.00
Melting point (Kelvin)
383.15
Boiling point (Celsius)
455.00
Boiling point (Kelvin)
728.15
General information
Molecular weight
379.49g/mol
Molar mass
379.8900g/mol
Density
1.3029g/cm3
Appearence

Droperidol hydrochloride typically appears as a white to near-white crystalline powder. It is often utilized in its powdered form for medical applications. The substance is odorless or nearly so, which makes it suitable for pharmaceutical use.

Comment on solubility

Solubility Insights for 5,5-diphenyl-2-[2-(1-piperidyl)ethyl]-1,3-dioxolan-4-one;hydrochloride

The solubility of the compound 5,5-diphenyl-2-[2-(1-piperidyl)ethyl]-1,3-dioxolan-4-one;hydrochloride is an important aspect to consider, especially in pharmaceutical applications. Here are some key points regarding its solubility:

  • Water Solubility: The hydrochloride salt form typically enhances the solubility in water due to the ionic nature of the compound.
  • Organic Solvents: It may show varying solubility in organic solvents, which can be influenced by the specific functional groups present.
  • pH Dependency: The solubility could be affected by the pH of the solution, making it relevant in biological systems where pH levels can fluctuate.
  • Temperature Effects: Increased temperature generally improves the solubility of solids, thus it could be beneficial to analyze solubility at different temperatures.

In conclusion, understanding the solubility of this compound is crucial for optimizing its use in formulations and predicting its behavior in biological systems. As with many compounds, solubility is a multifaceted property that is influenced by a variety of factors, making it essential to consider them comprehensively.

Interesting facts

Interesting Facts about 5,5-diphenyl-2-[2-(1-piperidyl)ethyl]-1,3-dioxolan-4-one; hydrochloride

The compound 5,5-diphenyl-2-[2-(1-piperidyl)ethyl]-1,3-dioxolan-4-one; hydrochloride is an intriguing substance within the realm of organic chemistry, primarily due to its structural complexity and potential applications. Here are some notable aspects:

  • Structural Significance: This compound features a unique dioxolane ring, known for its participation in various chemical reactions, particularly in the formation of more complex structures.
  • Piperidine Influence: The presence of a piperidine group suggests potential bioactivity. Piperidine is often found in many pharmacologically active compounds, making this derivative a point of interest for medicinal chemistry.
  • Applications in Research: Compounds like these are often studied for their potential as catalysts or intermediates in synthetic pathways. Researchers are particularly interested in their electronic properties influenced by the phenyl groups.
  • Pharmacological Potential: Preliminary studies indicate that variations of compounds containing piperidine and dioxolane moieties may exhibit activities such as anti-inflammatory or analgesic effects, although further investigations are required.
  • Salt Form: As a hydrochloride salt, this compound is likely to have enhanced solubility in water, which is advantageous for biological studies and medicinal formulation.

The fascinating chemistry behind 5,5-diphenyl-2-[2-(1-piperidyl)ethyl]-1,3-dioxolan-4-one; hydrochloride serves as a reminder of the vast landscape of organic compounds waiting to be explored. As chemists continue to delve into the synthesis and application of such molecules, the potential for new discoveries in fields like drug development and material science remains boundless.

Synonyms
Pipoxolan hydrochloride
Pipoxolan HCl
18174-58-8
Rowapraxin
VIA6WM647S
Br-18
DTXSID5057672
1,3-Dioxolan-4-one, 5,5-diphenyl-2-(2-piperidinoethyl)-, hydrochloride
DTXCID6031461
2-(beta-N-Piperidylethyl)-4,4-diphenyl-1,3-dioxolan-5-one hydrochloride
1,3-DIOXOLAN-4-ONE, 5,5-DIPHENYL-2-(2-(1-PIPERIDINYL)ETHYL)-, HYDROCHLORIDE
Pipoxolan hydrochloride [USAN]
5,5-Diphenyl-2-(2-piperidinoethyl)-1,3-dioxolan-4-one hydrochloride
5,5-diphenyl-2-(2-piperidin-1-ylethyl)-1,3-dioxolan-4-one;hydrochloride
Rowapraxin (TN)
Pipoxolan hydrochloride (USAN)
BR 18
UNII-VIA6WM647S
Pipoxolanhydrochlorid
5,5-Diphenyl-2-(2-(1-piperidinyl)ethyl)-1,3-dioxolan-4-one hydrochloride
SCHEMBL24264
orb1739327
CHEMBL2104727
JXNQXJVDHXGEPU-UHFFFAOYSA-N
PIPOXOLAN HYDROCHLORIDE [MI]
Tox21_113956
PIPOXOLAN HYDROCHLORIDE [MART.]
PIPOXOLAN HYDROCHLORIDE [WHO-DD]
NCGC00262965-01
CAS-18174-58-8
D05488
Q27291850
2-(.BETA.-N-PIPERIDYLETHYL)-4,4-DIPHENYL-1,3-DIOXOLAN-5-ONE HYDROCHLORIDE
5,5-DIPHENYL-2-(2'-PIPERIDINOETHYL)-1,3-DIOXOLAN-4-ONE HYDROCHLORIDE
1,3-DIOXOLAN-4-ONE, 5,5-DIPHENYL-2-(2-(1-PIPERIDINYL)ETHYL)-, HYDROCHLORIDE (1:1)