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5,6-Dichloro-2-nitro-1H-benzimidazole

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Identification
Molecular formula
C7H3Cl2N3O2
CAS number
22267-38-5
IUPAC name
5,6-dichloro-2-nitro-1H-benzimidazole
State
State

At room temperature, 5,6-Dichloro-2-nitro-1H-benzimidazole is in a solid state. It remains stable in this form under standard room conditions, maintaining its integrity and coloration without any alteration unless exposed to reactive conditions.

Melting point (Celsius)
251.00
Melting point (Kelvin)
524.15
Boiling point (Celsius)
391.00
Boiling point (Kelvin)
664.15
General information
Molecular weight
246.02g/mol
Molar mass
246.0230g/mol
Density
1.7000g/cm3
Appearence

5,6-Dichloro-2-nitro-1H-benzimidazole typically appears as a yellow crystalline solid. The crystals can vary in size, depending on the form in which the compound is crystallized, but they predominantly maintain a characteristic yellow hue due to the nitro group in the chemical structure.

Comment on solubility

Solubility of 5,6-Dichloro-2-nitro-1H-benzimidazole

5,6-Dichloro-2-nitro-1H-benzimidazole is a chemical compound of particular interest due to its unique structure, which influences its solubility characteristics.

In general, the solubility of this compound can be affected by several factors:

  • Polarity: The presence of nitro and chloro groups can enhance polarity, which can lead to differing solubility in polar versus nonpolar solvents.
  • Hydrogen Bonding: The functional groups may allow for hydrogen bonding with solvents, affecting solubility positively in polar solvents.
  • pH Dependence: The solubility may also vary with pH, as the ionization of certain groups could alter solubility in aqueous solutions.

As stated in solubility studies, “the solubility of organic compounds often varies significantly with minor changes in structure.” Thus, understanding the solubility of 5,6-dichloro-2-nitro-1H-benzimidazole requires careful consideration of the solvent used as well as the specific conditions of the experiment.

Typically, this compound is reported to have limited solubility in water, but better solubility in organic solvents like dimethyl sulfoxide (DMSO) or ethanol. As such, for practical applications, choosing an appropriate solvent is crucial for effective use.

Interesting facts

Interesting Facts about 5,6-Dichloro-2-Nitro-1H-Benzimidazole

5,6-Dichloro-2-nitro-1H-benzimidazole is a fascinating compound with a diverse range of applications and characteristics. Here are some intriguing aspects:

  • Structural Diversity: This compound features a benzimidazole core, a structure that is crucial in medicinal chemistry. Benzimidazoles are known for their biological activity, making them important in developing pharmaceuticals.

  • Antimicrobial Potential: Compounds containing nitro and chloro groups possess significant antimicrobial properties. Research indicates that 5,6-dichloro-2-nitro-1H-benzimidazole may exhibit activity against a range of pathogens, including bacteria and fungi.

  • Pharmaceutical Relevance: This compound is related to a class of medications used in treating various diseases. Its structural modifications can lead to derivatives with enhanced therapeutic effects.

  • Synthesis Insights: The synthesis of 5,6-dichloro-2-nitro-1H-benzimidazole often involves intricate organic reactions, showcasing the skill and precision required in synthetic chemistry. It challenges chemists to optimize yields and purities of the product.
  • Environmental Impact: Understanding the behavior and degradation of such compounds in the environment helps address ecological concerns. Studying their stability and breakdown can lead to more sustainable chemical practices.

Overall, the study of 5,6-dichloro-2-nitro-1H-benzimidazole offers valuable insights into both its chemical properties and its potential applications, helping propel scientific research forward.

Synonyms
5,6-Dichloro-2-nitrobenzimidazole
BENZIMIDAZOLE, 5,6-DICHLORO-2-NITRO-
10045-41-7
DTXSID50143294
DTXCID4065785