Skip to main content

Isatin

ADVERTISEMENT
Identification
Molecular formula
C8H7NO2
CAS number
91-56-5
IUPAC name
5,6-dihydroxy-1-methyl-indolin-3-one
State
State

At room temperature, Isatin is a solid compound. It readily crystallizes, which is an important property that aids in its purification.

Melting point (Celsius)
201.50
Melting point (Kelvin)
474.65
Boiling point (Celsius)
337.10
Boiling point (Kelvin)
610.25
General information
Molecular weight
147.15g/mol
Molar mass
147.1450g/mol
Density
1.2430g/cm3
Appearence

Isatin appears as an orange-red solid that forms into monoclinic crystals. It is noted for its bright color, which can vary slightly depending on impurities and hydratio...

Comment on solubility

Solubility of 5,6-dihydroxy-1-methyl-indolin-3-one

5,6-dihydroxy-1-methyl-indolin-3-one, with its complex structure, exhibits interesting solubility properties that can be influenced by several factors.

  • Solvent Polarity: The solubility in various solvents generally increases with the polarity of the solvent. For instance, this compound is more soluble in polar solvents such as water and methanol compared to non-polar solvents like hexane.
  • Temperature Effects: Higher temperatures often enhance solubility. When dissolved in hot solvents, the solubility of 5,6-dihydroxy-1-methyl-indolin-3-one is expected to increase due to increased molecular motion.
  • pH Influence: The solubility can also be significantly affected by the pH of the solution, given the presence of hydroxyl (-OH) groups that can partake in hydrogen bonding and ionization.

To summarize, the solubility of 5,6-dihydroxy-1-methyl-indolin-3-one is characterized by:

  1. Enhanced solubility in polar solvents
  2. Increased solubility with higher temperatures
  3. Dependence on pH conditions due to functional groups

Understanding these aspects can be crucial for applications involving this compound in various chemical and biological contexts.

Interesting facts

Interesting Facts about 5,6-Dihydroxy-1-methyl-indolin-3-one

The compound 5,6-dihydroxy-1-methyl-indolin-3-one is a fascinating member of the indole family, known for its diverse biological activities and applications in various fields. Here are some engaging insights about this intriguing compound:

  • Biochemical Significance: This compound is often studied for its potential antioxidant properties, which can contribute to the mitigation of oxidative stress in biological systems.
  • Pharmacological Potential: Research indicates that derivatives of indolinones, including 5,6-dihydroxy-1-methyl-indolin-3-one, have shown promise in the development of pharmaceuticals, particularly in cancer treatment.
  • Natural Sources: It has been reported that certain natural extracts contain this compound, highlighting its importance in phytochemistry and the study of medicinal plants.
  • Chemistry of Indole: The indole structure is notable for its presence in many natural compounds, especially in biological alkaloids, and serves as a core structure in drug discovery.

As scientists continue to explore the vast potential of compounds like 5,6-dihydroxy-1-methyl-indolin-3-one, the importance of understanding their chemical properties and biological effects becomes increasingly crucial. Its unique structure opens doors to numerous research opportunities and highlights the interconnectedness of chemistry and biology. As the famous quote goes, "Science is a way of thinking much more than it is a body of knowledge." This captures the essence of why studying such compounds can lead to groundbreaking discoveries!

Synonyms
1H-Indole-3,5,6-triol, 1-methyl-
BRN 0161691
INDOLE-3,5,6-TRIOL, 1-METHYL-
87708-46-1
SCHEMBL534210
UNII-0E3D10P8H9
DTXSID80214406
5,6-Dihydroxy-1-methylindolin-3-one
2,3-dihydro-5,6-dihydroxy-3-keto-N-methylindole
5-21-05-00536 (Beilstein Handbook Reference)
Q27236657