Skip to main content

Kojic acid

ADVERTISEMENT
Identification
Molecular formula
C6H6O4
CAS number
501-30-4
IUPAC name
5,6-dihydroxy-3-oxo-cyclohepta-1,4,6-triene-1-carboxylic acid
State
State

At room temperature, Kojic acid is a solid. It is often found in crystalline powder form.

Melting point (Celsius)
152.00
Melting point (Kelvin)
425.00
Boiling point (Celsius)
587.90
Boiling point (Kelvin)
861.10
General information
Molecular weight
142.11g/mol
Molar mass
142.1100g/mol
Density
1.5800g/cm3
Appearence

Kojic acid is a yellow-white crystalline powder. It is most commonly available in its white form and is often used in the cosmetic industry.

Comment on solubility

Solubility of 5,6-Dihydroxy-3-oxo-cyclohepta-1,4,6-triene-1-carboxylic acid

The solubility of 5,6-dihydroxy-3-oxo-cyclohepta-1,4,6-triene-1-carboxylic acid in various solvents is influenced by its unique chemical structure, primarily the presence of multiple hydroxyl (-OH) groups and a carboxylic acid (-COOH) functional group. These features enhance its ability to engage in hydrogen bonding, which can significantly affect its solubility characteristics.

Solubility Characteristics:

  • Polar Solvents: Compounds with hydroxyl and carboxylic acid groups tend to dissolve well in polar solvents such as water due to hydrogen bonding interactions.
  • Non-Polar Solvents: The presence of non-polar components in its structure may hinder solubility in non-polar solvents like hexane or cyclohexane.
  • pH Dependence: The solubility could also vary with pH; at lower pH levels, the carboxylic acid may be protonated, affecting solubility in polar media.

In conclusion, while 5,6-dihydroxy-3-oxo-cyclohepta-1,4,6-triene-1-carboxylic acid is likely to be more soluble in polar solvents, its solubility profile may vary depending on the solvent environment and the pH conditions. Understanding these factors is crucial for applications in chemical synthesis and formulation.

Interesting facts

Interesting Facts about 5,6-Dihydroxy-3-oxo-Cyclohepta-1,4,6-Triene-1-Carboxylic Acid

5,6-Dihydroxy-3-oxo-cyclohepta-1,4,6-triene-1-carboxylic acid is a fascinating compound that showcases the intricate world of organic chemistry. Here are some intriguing facts about this compound:

  • Cyclic Structure: The compound possesses a unique cyclic structure, which contributes to its chemical properties and reactivities. The presence of double bonds and hydroxyl groups in the cyclic framework is vital for its biological activity.
  • Potential Biological Activity: Compounds with similar structures often exhibit significant biological activities. They can be involved in various biochemical pathways, which may provide insights into medicinal chemistry and drug design.
  • Hydroxyl Groups: The two hydroxyl (-OH) functional groups make this compound an attractive candidate for hydrogen bonding, likely influencing its solubility and interaction with other molecules.
  • Use in Synthesis: The unique structural features of this compound can serve as intermediates in organic synthesis, paving the way for the development of novel derivatives with improved properties.
  • Historical Significance: Compounds structurally similar to this one have been studied for their roles in nature, including potential applications in agriculture and environmental science due to their influence on plant growth and health.

In summary, 5,6-dihydroxy-3-oxo-cyclohepta-1,4,6-triene-1-carboxylic acid not only represents a complex chemical structure but also stands at the intersection of various scientific disciplines, highlighting the endless possibilities within the realm of chemistry. As chemists continue to investigate such unique compounds, the door opens to new discoveries that can ultimately impact health, technology, and environmental sustainability.

Synonyms
Stipitatic acid
4440-39-5
3,6-Dihydroxy-5-oxo-1,3,6-cycloheptatriene-1-carboxylic acid
Stipitatate
35DNB4NP54
1,3,6-CYCLOHEPTATRIENE-1-CARBOXYLIC ACID, 3,6-DIHYDROXY-5-OXO-
5,6-dihydroxy-3-oxocyclohepta-1,4,6-triene-1-carboxylic acid
3,6-dihydroxy-5-oxocyclohepta-1,3,6-triene-1-carboxylic acid
BRN 2723909
UNII-35DNB4NP54
4-10-00-03859 (Beilstein Handbook Reference)
SCHEMBL21100915
CHEBI:15957
DTXSID80891817
ZGKNMKBZOSTFCB-UHFFFAOYSA-N
NS00094889
C01853
Q27098321
4,6-DIHYDROXY-3-OXOCYCLOHEPTA-1,4,6-TRIENE-1-CARBOXYLIC ACID