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Dihydroorotic acid

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Identification
Molecular formula
C6H8N2O4
CAS number
5988-19-2
IUPAC name
5,6-dihydroxy-5-methyl-hexahydropyrimidine-2,4-dione
State
State

At room temperature, dihydroorotic acid is typically found in a solid state as a crystalline powder.

Melting point (Celsius)
241.00
Melting point (Kelvin)
514.00
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.00
General information
Molecular weight
157.14g/mol
Molar mass
157.1400g/mol
Density
1.6000g/cm3
Appearence

Dihydroorotic acid appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 5,6-dihydroxy-5-methyl-hexahydropyrimidine-2,4-dione

The solubility characteristics of 5,6-dihydroxy-5-methyl-hexahydropyrimidine-2,4-dione can be understood through several key factors:

  • Polarity: Due to the presence of multiple hydroxyl (-OH) groups, the compound exhibits a high degree of polarity. This increases its affinity for polar solvents such as water.
  • Hydrogen Bonding: The hydroxyl groups can participate in hydrogen bonding, enhancing solubility in protic solvents. This feature is crucial for its interaction in biological systems.
  • Solvent Dependency: While it shows considerable solubility in water owing to its polar nature, it may show variable solubility in organic solvents. Nowhere does it equal the solubility seen in polar solvents.

To summarize, one might say, "The more hydroxyl groups present, the more likely the compound is to dissolve in water." Hence, for 5,6-dihydroxy-5-methyl-hexahydropyrimidine-2,4-dione, expect a good solubility profile in aqueous environments while remaining selective in organic solvent interactions.

Interesting facts

Interesting Facts About 5,6-Dihydroxy-5-methyl-hexahydropyrimidine-2,4-dione

5,6-Dihydroxy-5-methyl-hexahydropyrimidine-2,4-dione is a fascinating compound that showcases the complexity and richness of organic chemistry. This compound is of particular interest due to its unique structure and potential applications in various fields:

  • Bioactivity: Compounds like 5,6-dihydroxy-5-methyl-hexahydropyrimidine-2,4-dione are often studied for their biological activities. They may exhibit activities such as antimicrobial or anti-inflammatory properties, making them potential candidates for pharmaceutical development.
  • Synthesis Challenges: The synthesis of this compound involves intricate reactions, often requiring specialized techniques and conditions. It’s a great example of how organic synthesis can be both an art and a science.
  • Structural Versatility: The presence of multiple hydroxyl groups in its structure suggests opportunities for further derivatization. This can lead to the creation of analogues with desirable properties, broadening its applicability.
  • Research Potential: Scientists are continuously exploring new avenues for utilizing compounds like this in materials science, medicinal chemistry, and biochemistry. Its unique properties can lead to discoverable pathways in research.

The allure of 5,6-dihydroxy-5-methyl-hexahydropyrimidine-2,4-dione lies in its intricate balance between stability and reactivity. As stated by renowned chemist Linus Pauling, "There is no such thing as a neutral molecule; all molecules have a sense of direction in which they will react." This compound epitomizes the dynamic nature of chemical substances, where understanding their properties can lead to groundbreaking innovations.

In conclusion, the study of 5,6-dihydroxy-5-methyl-hexahydropyrimidine-2,4-dione not only enhances our knowledge of structural organic chemistry but also opens doors to potential applications that can significantly impact various scientific disciplines.

Synonyms
Thymine glycol
2943-56-8
Thy glycol
5,6-dihydroxy-5-methyl-1,3-diazinane-2,4-dione
5,6-Dihydroxy-5,6-dihydrothymine
HYDROURACIL, 5,6-DIHYDROXY-5-METHYL-
5,6-dihydroxy-5-methyldihydropyrimidine-2,4(1H,3H)-dione
Glycolthymine
5-methyl-4,5-dihydropyrimidine-2,4,5,6-tetrol
SCHEMBL48043
5,6-Dihydroxydihydro-thymine
CHEBI:29128
GUKSGXOLJNWRLZ-UHFFFAOYSA-N
DTXSID601317323
2,4(1H,3H)-Pyrimidinedione, dihydro-5,6-dihydroxy-5-methyl-
2,4-(1H,3H)-Pyrimidinedione, dihydro-5,6-dihydroxy-5-methyl-
AKOS006373640
Q21099627
5,6-Dihydroxy-5-methyldihydro-2,4(1H,3H)-pyrimidinedione #