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Leukotriene B4

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Identification
Molecular formula
C20H32O4
CAS number
71160-24-2
IUPAC name
5,6-dihydroxyicosa-7,9,11,14-tetraenoic acid
State
State
At room temperature, leukotriene B4 typically exists in a liquid state if studied in biological systems, due to its origin as a lipid mediator. It may also be available as a solid form (crystalline or powder) under certain conditions for biochemical research purposes.
Melting point (Celsius)
-40.00
Melting point (Kelvin)
233.15
Boiling point (Celsius)
625.15
Boiling point (Kelvin)
898.30
General information
Molecular weight
336.54g/mol
Molar mass
336.5390g/mol
Density
1.0540g/cm3
Appearence

Leukotriene B4 (LTB4) is often encountered in liquid form or as a crystalline solid, depending on the method of preparation and storage conditions. As a member of the lipid class of substances, it is usually clear to pale yellow, possibly exhibiting some viscous properties under certain conditions. Due to its biochemical activity, it is often handled in solution rather than as a dry substance.

Comment on solubility

Solubility of 5,6-Dihydroxyicosa-7,9,11,14-tetraenoic Acid (C20H32O4)

The solubility characteristics of 5,6-dihydroxyicosa-7,9,11,14-tetraenoic acid can be quite intriguing due to its unique chemical structure. This compound, being a polyunsaturated fatty acid derivative, exhibits specific solubility patterns in various solvents.

Key Points on Solubility:

  • Polar Solvents: This compound is expected to have limited solubility in water due to the large non-polar hydrocarbon chain, which decreases the overall polarity.
  • Non-Polar Solvents: Conversely, it is likely to be soluble in organic solvents such as hexane, chloroform, or ether, where its hydrophobic characteristics can be accommodated.
  • Hydrogen Bonding: The presence of hydroxyl (-OH) groups allows for potential hydrogen bonding in alcohols or other polar solvents, which can enhance solubility to some extent in those mediums.

In summary, the solubility of 5,6-dihydroxyicosa-7,9,11,14-tetraenoic acid is largely influenced by its molecular structure, with a pronounced preference for non-polar environments and greater challenges in polar solvents. Remember, "like dissolves like," and this compound beautifully illustrates this principle!

Interesting facts

Interesting Facts about 5,6-Dihydroxyicosa-7,9,11,14-tetraenoic Acid

5,6-dihydroxyicosa-7,9,11,14-tetraenoic acid, commonly referred to as di-hydroxyicosatetraenoic acid (DHTA), is an intriguing compound that plays a significant role in various biochemical processes. Here are some captivating aspects of this molecule:

  • Biological Importance: DHTA is known to be involved in the metabolism of polyunsaturated fatty acids, specifically arachidonic acid, which is vital for producing eicosanoids—key signaling molecules that regulate inflammation and immune responses.
  • Synthesis: This compound is synthesized through the enzymatic action of lipoxygenases and cytochrome P450 enzymes, which convert omega-3 and omega-6 fatty acids into more complex structures like DHTA.
  • Physiological Functions: DHTA has been shown to have potential antioxidant properties and contributes to cardiovascular health by influencing vasodilation and platelet aggregation.
  • Research Applications: Scientists have been exploring DHTA in the context of its role in various diseases, including arthritis, cardiovascular diseases, and cancer, as it may impact the inflammatory processes associated with these conditions.
  • Natural Sources: This acid can be found in fish oil and some plant oils, making it an interesting subject for those examining dietary sources of fatty acids and their health implications.

In summary, 5,6-dihydroxyicosa-7,9,11,14-tetraenoic acid exemplifies the complex interplay between essential fatty acids and human health, highlighting the importance of understanding the biochemical pathways these compounds participate in. As research continues to evolve, the potential benefits and mechanisms of DHTA are likely to reveal even more astonishing insights into its role in biology.

Synonyms
5(S),6(R)-diHETE
5,6-dihydroxyicosa-7,9,11,14-tetraenoic acid
PD046948