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Cimbi-5

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Identification
Molecular formula
C22H27N3O2
CAS number
150431-07-5
IUPAC name
5,6-dimethoxy-2-methyl-3-[2-(4-phenylpiperazin-1-yl)ethyl]-1H-indole
State
State

At room temperature, this compound is typically in a solid state, appearing as a crystalline powder.

Melting point (Celsius)
171.60
Melting point (Kelvin)
444.80
Boiling point (Celsius)
492.50
Boiling point (Kelvin)
765.70
General information
Molecular weight
369.49g/mol
Molar mass
369.4860g/mol
Density
1.2400g/cm3
Appearence

5,6-dimethoxy-2-methyl-3-[2-(4-phenylpiperazin-1-yl)ethyl]-1H-indole is a complex organic compound characterized by its distinctive structure. It generally appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 5,6-Dimethoxy-2-methyl-3-[2-(4-phenylpiperazin-1-yl)ethyl]-1H-indole

The solubility of the compound 5,6-dimethoxy-2-methyl-3-[2-(4-phenylpiperazin-1-yl)ethyl]-1H-indole, with the formula C22H27N3O2, can be quite intriguing due to its complex molecular structure. Factors influencing its solubility include:

  • Molecular Polarity: With multiple methoxy groups, this compound exhibits moderate polarity, which can increase its interaction with polar solvents.
  • Hydrogen Bonding: The presence of nitrogen atoms may facilitate hydrogen bonding, enhancing solubility in protic solvents.
  • Alkyl Chain Influence: The long alkyl side chains can lead to hydrophobic character, which might reduce solubility in water but improve solubility in organic solvents.

Empirical studies tend to suggest that:

  • This compound shows greater solubility in organic solvents such as ethanol or dimethyl sulfoxide (DMSO).
  • It may exhibit relatively low solubility in aqueous solutions, making it less favorable for dissolution in water-based environments.

In conclusion, the solubility of 5,6-dimethoxy-2-methyl-3-[2-(4-phenylpiperazin-1-yl)ethyl]-1H-indole depends on a dynamic balance between its polar and non-polar characteristics. This nuanced solubility profile highlights the importance of considering both chemical structure and solvent interaction when evaluating solubility for compounds of this nature.

Interesting facts

5,6-Dimethoxy-2-methyl-3-[2-(4-phenylpiperazin-1-yl)ethyl]-1H-indole

This intriguing compound belongs to the indole class of compounds, which are known for their diverse range of biological activities. More specifically, this compound is a derivative of an indole, making it an interesting subject for research in the fields of pharmacology and medicinal chemistry.

Key Features:

  • Pharmacological Potential: Compounds of this nature are often investigated for their potential therapeutic effects, including anti-depressant or anti-anxiety properties.
  • Structural Complexity: The presence of dimethoxy groups on the indole ring contributes to the compound's unique chemical behavior and interaction with biological targets.
  • Mechanism of Action: The incorporation of a piperazine ring in its structure is notable, as this moiety is frequently found in pharmaceuticals that target the central nervous system.

Researchers synthetically produce this compound to explore its effects on neurotransmitter systems, particularly serotonin and dopamine pathways, which are crucial in mood regulation. The phenylpiperazine segment is particularly interesting, as it is known for enhancing selective serotonin reuptake inhibition.

In the words of renowned chemist, “Each compound tells a story uniquely its own; the challenge is to decode its narrative.” This compound certainly has a story worth investigating, highlighting not only the fascinating complexity of its structure but also the limitless potential that indole derivatives offer in modern medicinal chemistry.

Overall, 5,6-dimethoxy-2-methyl-3-[2-(4-phenylpiperazin-1-yl)ethyl]-1H-indole exemplifies the intersection of complexity and utility that is hallmark to chemical research, opening doors for novel therapeutic avenues.

Synonyms
oxypertine
153-87-7
Equipertine
Forit
Opertil
Oxipertina
Oxipertinum
Oxypertinum
Oxipertine
Oxypertinum [INN-Latin]
Oxipertina [INN-Spanish]
WIN 18501-2
Oxypertine [USAN:INN:BAN:JAN]
EINECS 205-818-3
DO 180
BRN 0899339
5JGL4G25R7
Forit (TN)
WIN 18,501-2
5,6-dimethoxy-2-methyl-3-[2-(4-phenylpiperazin-1-yl)ethyl]-1H-indole
1H-Indole, 5,6-dimethoxy-2-methyl-3-(2-(4-phenyl-1-piperazinyl)ethyl)-
OXYPERTINE [MI]
OXYPERTINE [INN]
OXYPERTINE [JAN]
OXYPERTINE [USAN]
WIN-185012
OXYPERTINE [MART.]
OXYPERTINE [WHO-DD]
WIN-18501-2
DTXSID20165185
5,6-Dimethoxy-2-methyl-3-(2-(4-phenyl-1-piperazinyl)ethyl)indole
5,6-Dimethoxy-2-methyl-3-[2-(4-phenyl-1-piperazinyl)ethyl]-1H-indole
5-23-03-00112 (Beilstein Handbook Reference)
5,6-Dimethoxy-2-methyl-3-[2-(4-phenyl-1-piperazinyl)ethyl]indole
Oxypertinum (INN-Latin)
5,6-dimethoxy-2-methyl-3-(2-(4-phenylpiperazin-1-yl)ethyl)-1H-indole
Oxipertina (INN-Spanish)
OXYPERTINE (MART.)
Oxypertin
NCGC00183866-01
UNII-5JGL4G25R7
1H-Indole, 5,6-dimethoxy-2-methyl-3-[2-(4-phenyl-1-piperazinyl)ethyl]-
SCHEMBL1515
Oxypertine (JAN/USAN/INN)
CHEMBL2107011
DTXCID8087676
CHEBI:31952
N05AE01
AAA15387
AKOS040749106
INDOLE, 5,6-DIMETHOXY-2-METHYL-3-(2-(4-PHENYL-1-PIPERAZINYL)ETHYL)-
DB13403
DA-56520
HY-119677
CS-0077804
NS00008962
D01219
Q7116102
5,6-Dimethoxy-2-methyl-3-[2-(4-phenyl-1-piperazinyl)ethyl]-1H-indole #
205-818-3