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5,6-Dimethoxytetralin-2-amine

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Identification
Molecular formula
C12H17NO2
CAS number
7410-56-8
IUPAC name
5,6-dimethoxytetralin-2-amine
State
State
At room temperature, 5,6-Dimethoxytetralin-2-amine is typically found in a solid state.
Melting point (Celsius)
48.60
Melting point (Kelvin)
321.75
Boiling point (Celsius)
233.70
Boiling point (Kelvin)
506.85
General information
Molecular weight
207.25g/mol
Molar mass
207.2530g/mol
Density
1.1980g/cm3
Appearence

5,6-Dimethoxytetralin-2-amine generally appears as a solid at room temperature. The compound may have a crystalline form and could be white to off-white in color.

Comment on solubility

Solubility of 5,6-Dimethoxytetralin-2-amine

The solubility of 5,6-dimethoxytetralin-2-amine can significantly impact its applications in various chemical and pharmaceutical processes. Understanding its solubility characteristics is crucial for effective formulation and usage.

Key Factors Influencing Solubility:

  • Polarity: Due to the presence of methoxy groups, the polarity of 5,6-dimethoxytetralin-2-amine is elevated, which can enhance solubility in polar solvents.
  • Hydrogen Bonding: The amine group can engage in hydrogen bonding, potentially increasing solubility in water as well as in alcohols and other protic solvents.
  • Hydrophobic Interactions: The tetralin structure presents a hydrophobic character, which may lead to decreased solubility in non-polar solvents.

When considering solubility, it is essential to note that:

  1. Solvent Type: The choice of solvent plays a significant role. For example, solvents like methanol and ethanol may dissolve this compound more readily compared to hexane or other non-polar solvents.
  2. Temperature: Generally, increased temperature can enhance solubility, but this must be empirically determined for specific compounds.
  3. Compound Form: The solubility can also be affected by the form of the compound, such as whether it is in a pure or salt form.

In summary, the solubility of 5,6-dimethoxytetralin-2-amine is influenced by multiple factors, primarily its functional groups and the nature of the solvent. Proper understanding of these aspects is critical for predicting behavior in solution and optimizing usage in various applications.

Interesting facts

Interesting Facts about 5,6-Dimethoxytetralin-2-amine

5,6-Dimethoxytetralin-2-amine is a fascinating compound that has attracted the attention of chemists and pharmacologists alike due to its unique structure and potential applications. Here are some interesting aspects of this compound:

  • Structural Significance: This compound belongs to the family of tetralins, which are bicyclic compounds that feature a fused aromatic ring system. The presence of the two methoxy groups at the 5 and 6 positions introduces interesting electronic properties that can influence the compound’s reactivity and stability.
  • Biological Relevance: 5,6-Dimethoxytetralin-2-amine is studied for its potential pharmacological activities, which may include effects on neurotransmitter systems. Research indicates that compounds with similar structures can exhibit various biological activities, making this compound a subject of interest in medicinal chemistry.
  • Synthesis Challenges: The synthesis of this compound may involve intricate multi-step processes, often requiring careful selection of reagents and conditions to ensure optimal yield and purity. This aspect makes it a great candidate for students learning about organic synthesis techniques.
  • Research Horizons: Current research might focus on how modifications in the structure of 5,6-dimethoxytetralin-2-amine could lead to the development of new therapeutic agents. Scientists are particularly keen on understanding how small changes at the molecular level can yield significant differences in biological activity.
  • Future Applications: As research progresses, this compound might reveal its potential in the treatment of various neurological disorders, showcasing how organic compounds can lead to advancements in pharmaceutical development.

In summary, 5,6-dimethoxytetralin-2-amine is not just a chemical entity but a compound that represents the intersection of chemistry and biology. Its ongoing study emphasizes the importance of understanding the intricate relationships between molecular structure and biological function.

Synonyms
21489-50-9
1,2,3,4-Tetrahydro-5,6-dimethoxy-2-naphthylamine
5,6-dimethoxy-1,2,3,4-tetrahydronaphthalen-2-amine
DTXSID10944082
beta-Naphthylamine, 5,6-dimethoxy-1,2,3,4-tetrahydro-
RefChem:1072203
5,6-Dimethoxy-1,2,3,4-tetrahydro-beta-naphthylamine
SCHEMBL6546842
5,6-dimethoxy-2-amino-tetralin
DTXCID70968441
BDHOUGWYKHSPIX-UHFFFAOYSA-N
2-NAPHTHYLAMINE, 1,2,3,4-TETRAHYDRO-5,6-DIMETHOXY-
PD033611
1,2,3,4-tetrahydro-5,6-dimethoxy-2- aminonaphthalene