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5,6-Dimethyl-2-nitrobenzimidazole

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Identification
Molecular formula
C9H9N3O2
CAS number
63478-00-2
IUPAC name
5,6-dimethyl-2-nitro-1H-benzimidazole
State
State

At room temperature, 5,6-Dimethyl-2-nitrobenzimidazole is a solid substance. It usually exists in a stable crystalline form under normal conditions.

Melting point (Celsius)
182.00
Melting point (Kelvin)
455.15
Boiling point (Celsius)
216.00
Boiling point (Kelvin)
489.15
General information
Molecular weight
191.20g/mol
Molar mass
191.1960g/mol
Density
1.3710g/cm3
Appearence

5,6-Dimethyl-2-nitrobenzimidazole is a crystalline solid that can be off-white or yellowish in color. It typically forms as fine, powdery crystals.

Comment on solubility

Solubility of 5,6-dimethyl-2-nitro-1H-benzimidazole

The solubility of 5,6-dimethyl-2-nitro-1H-benzimidazole is an interesting topic to explore, especially considering its various structural components that influence solubility behavior in different solvents.

  • Polar solvents: The presence of the nitro group in its structure may lead to moderate solubility in polar solvents such as water, as the nitro group can engage in hydrogen bonding.
  • Non-polar solvents: Conversely, its methyl groups can enhance compatibility with non-polar solvents, suggesting better solubility in organic solvents like ethanol or acetone.
  • Temperature dependence: As is common with many organic compounds, the solubility of 5,6-dimethyl-2-nitro-1H-benzimidazole is likely to increase with temperature, which assists in breaking intermolecular interactions.

To summarize, while 5,6-dimethyl-2-nitro-1H-benzimidazole may exhibit variable solubility based on the solvent polarity and temperature, understanding its solubility potential is crucial for applications in fields like pharmaceuticals and material science. As one notable observation states, “**the interplay of structural features dramatically affects solubility profiles**.”

Interesting facts

Interesting Facts about 5,6-Dimethyl-2-nitro-1H-benzimidazole

5,6-Dimethyl-2-nitro-1H-benzimidazole is a fascinating compound that showcases the interplay between organic chemistry and medicinal applications. Here are some engaging insights:

  • Biological Significance: This compound belongs to the benzimidazole family, which is significant in pharmacology due to its presence in various drugs that exhibit anti-parasitic, anti-fungal, and anti-cancer properties.
  • Structural Features: The presence of both methyl and nitro groups in its structure allows for unique electronic and steric properties, making it an interesting candidate for further research in lead optimization.
  • Versatility: Compounds like 5,6-dimethyl-2-nitro-1H-benzimidazole are often utilized as intermediates in the synthesis of more complex molecules. This makes them valuable in the development of novel pharmaceuticals.
  • Interactions with Biological Targets: Research suggests that benzimidazoles can inhibit crucial enzymes in pathogens, which is why their derivatives are essential for drug design against certain diseases.
  • Safety and Toxicity: While this compound has potential benefits, understanding its safety profile is crucial for clinical applications. Investigating toxicity and interaction with biological systems is a key area of ongoing research.

This compound’s unique properties not only make it a subject of academic study but also a potential player in future medicinal advancements. Understanding its chemistry can lead to breakthroughs in the treatment of various ailments, proving that even seemingly simple compounds can have a significant impact!

Synonyms
BENZIMIDAZOLE, 5,6-DIMETHYL-2-NITRO-
5709-69-3
BRN 0958459
5,6-Dimethyl-2-nitrobenzimidazole
5-23-06-00461 (Beilstein Handbook Reference)
DTXSID30205708
AKOS006279832
DB-285554