5,6-Dinitro-2-(trifluoromethyl)-1H-benzimidazole

Identification

Molecular formula

C₈H₃F₃N₄O₄

CAS number

139444-64-1

IUPAC name

5,6-dinitro-2-(trifluoromethyl)-1H-benzimidazole

State

At room temperature, the compound is in a solid state.

Melting point (Celsius)

174.00

Melting point (Kelvin)

447.15

Boiling point (Celsius)

358.00

Boiling point (Kelvin)

631.15

General information

Molecular weight

290.13g/mol

Molar mass

290.1300g/mol

Density

1.7400g/cm³

Appearence

The compound typically appears as a yellow crystalline solid.

Comment on solubility

Solubility of 5,6-Dinitro-2-(trifluoromethyl)-1H-benzimidazole

The solubility of 5,6-dinitro-2-(trifluoromethyl)-1H-benzimidazole is influenced by its chemical structure, which includes both nitro and trifluoromethyl groups. Understanding its solubility characteristics is essential for various applications in chemical research and industry.

Key points about the solubility of this compound include:

Polar vs Non-Polar Solvents: Due to the presence of polar nitro groups, this compound may exhibit higher solubility in polar organic solvents. In contrast, its trifluoromethyl group adds a degree of hydrophobic character, making it less soluble in aqueous environments.
Temperature Dependency: As with many chemical compounds, solubility can vary with temperature. Typically, increased temperature leads to greater solubility in solvents.
pH Influence: The acidity or basicity of the environment can significantly impact solubility. For instance, in a more acidic medium, protonation of certain functional groups can enhance solubility.
Stability of the Compound: At high concentrations, solubility may lead to precipitation or degradation, particularly for sensitive compounds like this one.

In summary, while the solubility of 5,6-dinitro-2-(trifluoromethyl)-1H-benzimidazole can be influenced by several factors, its polar characteristics make it generally soluble in polar solvents but less so in water. As always, it's important to carry out specific solubility tests to determine its behavior in different environments.

Interesting facts

Interesting Facts about 5,6-Dinitro-2-(trifluoromethyl)-1H-benzimidazole

5,6-Dinitro-2-(trifluoromethyl)-1H-benzimidazole is a fascinating compound that presents unique properties and applications in the field of chemistry. Here are some intriguing aspects of this compound:

Structural Significance: The compound features a benzimidazole ring, which is a bicyclic structure known for its biological activity and potential in pharmaceutical formulations.
Nitro Groups: The presence of two nitro groups at the 5 and 6 positions enhances its reactivity and allows for a variety of chemical modifications, making it a versatile building block for further synthesis.
Trifluoromethyl Group: The trifluoromethyl group at position 2 is notable for imparting unique electronic properties and lipophilicity, which significantly influence the compound's behavior in biological systems.
Applications in Research: Compounds of this nature are often studied for their potential application in drug discovery, specifically in targeting certain enzymes or receptors in various diseases.
Analytical Interest: The distinctive characteristics of 5,6-dinitro-2-(trifluoromethyl)-1H-benzimidazole make it a subject of interest in analytical chemistry, where it can be used as a standard reference compound in various spectroscopic techniques.

Given its unique structure and properties, this compound exemplifies the intricate relationship between structure and function in molecular chemistry. Chemists continue to explore the myriad possibilities that such compounds offer, underscoring the importance of compounds like 5,6-dinitro-2-(trifluoromethyl)-1H-benzimidazole in advancing scientific knowledge and innovative applications.

Synonyms

BENZIMIDAZOLE, 5,6-DINITRO-2-(TRIFLUOROMETHYL)-

2338-24-1

BRN 0625375

5,6-Dinitro-2-(trifluoromethyl)benzimidazole

5-23-06-00374 (Beilstein Handbook Reference)

CHEMBL226920

DTXSID50177933

OOJCWFWANPATNU-UHFFFAOYSA-N