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Leukotriene B4

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Identification
Molecular formula
C20H32O4
CAS number
71160-24-2
IUPAC name
5,6,15-trihydroxyicosa-7,9,11,13-tetraenoic acid
State
State
At room temperature, leukotriene B4 is usually found as a component of biological samples, being a liquid derived from lipids of cell membranes.
Melting point (Celsius)
-30.00
Melting point (Kelvin)
243.15
Boiling point (Celsius)
230.00
Boiling point (Kelvin)
503.15
General information
Molecular weight
336.47g/mol
Molar mass
336.4690g/mol
Density
1.0267g/cm3
Appearence

Leukotriene B4 is typically not isolated in a pure form for storage or practical use because it is a biological mediator. However, when described, it is a colorless or pale yellow oily liquid, given its origin from lipids.

Comment on solubility

Solubility of 5,6,15-Trihydroxyicosa-7,9,11,13-tetraenoic Acid

The solubility of 5,6,15-trihydroxyicosa-7,9,11,13-tetraenoic acid (C20H32O4), commonly known as a type of polyunsaturated fatty acid, can be quite complex, influenced by several factors. Here are the primary considerations regarding its solubility:

  • Polarity: This compound contains multiple hydroxyl (-OH) functional groups, which contribute to its polar nature. As a result, it tends to be more soluble in polar solvents, such as water, compared to non-polar solvents.
  • Hydrogen Bonding: The presence of hydroxyl groups allows for hydrogen bonding with solvent molecules, enhancing solubility in alcohols and other polar environments.
  • Saturation: The *unsaturated* nature due to multiple double bonds may decrease solubility in fully saturated solvents, while it is generally better soluble in *fatty matrices* and emulsions.
  • Temperature Dependency: Increasing temperature typically increases solubility, so heating the solvent may enhance the dissolution of this compound.

In practical applications, understanding the solubility behavior of this compound is crucial for its utilization in biochemical and pharmaceutical contexts, especially when creating formulations that require optimal bioavailability.

In conclusion, while 5,6,15-trihydroxyicosa-7,9,11,13-tetraenoic acid exhibits favorable solubility characteristics in polar environments, factors such as polarity, hydrogen bonding capability, and temperature play significant roles in determining its overall solubility profile.

Interesting facts

Interesting Facts About 5,6,15-Trihydroxyicosa-7,9,11,13-tetraenoic Acid

5,6,15-trihydroxyicosa-7,9,11,13-tetraenoic acid, commonly referred to in scientific literature as a member of the group of polyunsaturated fatty acids, presents a fascinating subject of study due to its diverse biological activities.

  • Biological Significance: This compound is known to play a role in various physiological processes, including inflammation and cellular signaling. Its structure suggests potential involvement in modulating immune responses.
  • Analytical Interest: The hydroxyl groups present in its structure offer sites for potential chemical modifications, making it an intriguing candidate for research in synthetic organic chemistry.
  • Source of Inspiration: 5,6,15-trihydroxyicosa-7,9,11,13-tetraenoic acid serves as a precursor for the synthesis of bioactive lipids, which can inspire drug development, especially in targeting chronic diseases.
  • Research Applications: Studies have suggested its potential role in cardiovascular health, suggesting that understanding its mechanisms could lead to enhanced therapeutic strategies.
  • Natural Occurrence: Found in various biological systems, this compound highlights the importance of omega fatty acids in nutrition and metabolism.

As stated by one influential researcher in the field, "Understanding the intricate details of fatty acid metabolism can unveil new therapeutic targets for a variety of diseases." This emphasizes the potential of 5,6,15-trihydroxyicosa-7,9,11,13-tetraenoic acid not just as a chemical entity but as a vital part of our biochemical landscape.

In conclusion, the exploration of 5,6,15-trihydroxyicosa-7,9,11,13-tetraenoic acid embodies both challenges and opportunities for future research, holding promise for advancements in health and disease management.

Synonyms
lipoxin-A4
5(S),6(S)-Lipoxin A4