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Tetrahydropapaverinium chloride

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Identification
Molecular formula
C11H14ClNO2
CAS number
77008-19-8
IUPAC name
5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium;chloride
State
State

At room temperature, tetrahydropapaverinium chloride is in a solid state. It is typically found in laboratories in this form for various research and chemical synthesis applications.

Melting point (Celsius)
210.00
Melting point (Kelvin)
483.00
Boiling point (Celsius)
290.00
Boiling point (Kelvin)
563.00
General information
Molecular weight
261.72g/mol
Molar mass
261.7230g/mol
Density
1.2000g/cm3
Appearence

Tetrahydropapaverinium chloride appears as a white to off-white crystalline powder. It is typically odorless and is hygroscopic, meaning it can absorb moisture from the air.

Comment on solubility

Solubility of 5,6,7,8-Tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium; Chloride

The solubility of 5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium chloride in various solvents can provide significant insight into its chemical behavior and potential applications. In general, several factors influence the solubility of this compound:

  • Polarity: Being a quaternary ammonium salt, the chloride anion enhances the overall polarity of the molecule, often leading to good solubility in polar solvents.
  • Hydrogen Bonding: The presence of oxygen atoms in the dioxolo structure may facilitate hydrogen bonding, which could increase solubility in protic solvents such as water and alcohols.
  • Temperature Effect: Like many chemical compounds, solubility may vary with temperature. As temperature increases, solubility may also increase for this chloride salt.
  • Concentration: Higher concentrations of certain solutes can cause precipitation, so careful consideration of the concentration is essential when calculating solubility limits.

In conclusion, while specific solubility data for 5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium chloride in various solvents may not be readily available, it is reasonable to expect it will demonstrate good solubility in polar solvents due to its ionic nature and potential for hydrogen bonding. This characteristic can make it useful in various applications, particularly in the realms of medicinal chemistry or pharmaceutical formulation.

Interesting facts

Interesting Facts about 5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium;chloride

This intriguing compound, commonly referred to as a derivative of isoquinoline, presents a fascinating area of study within the realm of organic chemistry. Here are some notable points:

  • Structural Complexity: The structure of this compound features a unique dioxole component, which contributes to its distinctive properties and facilitates various chemical reactions.
  • Biological Relevance: Derivatives of isoquinolines are often found to exhibit biological activity, including potential roles in pharmacology as neuroprotective or antitumor agents. This compound may pave the way for the development of new therapeutic agents.
  • Synthetic Accessibility: The synthesis of such compounds often involves intricate processes, yet they are synthesized to explore their properties and biochemical interactions, enhancing our understanding of complex organic molecules.
  • Chloride as a Counter Ion: The presence of chloride ions in the compound plays a significant role in solubility and stability, which is crucial for its potential applications in various chemical environments.

Quote to Consider

As noted by chemists in the field, "The study of isoquinoline derivatives not only unveils the versatility of organic compounds but also bridges the gap between synthetic chemistry and pharmacological research."

This compound’s intricate design and potential applications make it an exciting subject for further exploration in medicinal chemistry!

Synonyms
5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium;chloride
NSC 112981
6,7-Methylenedioxy-1,2,3,4-tetrahydroisoquinoline hydrochloride
UNII-N2NE2TM9ZF
AKOS004907220