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Daidzein

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Identification
Molecular formula
C15H10O4
CAS number
486-66-8
IUPAC name
5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one
State
State

Daidzein is in a solid state at room temperature. It typically exists as a crystalline powder.

Melting point (Celsius)
315.00
Melting point (Kelvin)
588.00
Boiling point (Celsius)
491.40
Boiling point (Kelvin)
764.60
General information
Molecular weight
254.24g/mol
Molar mass
254.2360g/mol
Density
1.3170g/cm3
Appearence

Daidzein appears as a white to off-white crystalline powder. It is practically insoluble in water but soluble in organic solvents such as ethanol and dimethyl sulfoxide.

Comment on solubility

Solubility of 5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one (C15H10O4)

The solubility of 5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one, commonly known as a flavonoid compound, demonstrates interesting characteristics that are influenced by its molecular structure. Here are several important points regarding its solubility:

  • Polar Nature: Due to the presence of multiple hydroxyl groups, the compound exhibits a polar nature which enhances its potential for solubility in polar solvents such as water.
  • Solvent Variability: It is generally expected to have higher solubility in organic solvents, including ethanol and methanol, where intermolecular interactions are more favorable.
  • Concentration Dependency: The solubility may vary with concentration and temperature; thus, solubility tests are frequently conducted to identify optimal conditions.
  • Hydrogen Bonding: The ability of the hydroxyl (-OH) groups to form hydrogen bonds plays a significant role in solubilizing the compound in suitable media.

As with many flavonoids, the solubility properties can influence its bioavailability and therapeutic potential. Understanding the solubility behavior of 5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one may yield insights into its functional applications, making it a compound of interest for further study in chemical and pharmaceutical research.

Interesting facts

Interesting Facts about 5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one

5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one, commonly referred to as a flavonoid compound, holds a special place in the world of natural products and pharmaceuticals. Here are some notable aspects that showcase its importance:

  • Natural Occurrence: This compound is typically found in a variety of plants, particularly in herbs and fruits. Its presence contributes to the color and flavor of these botanical sources.
  • Health Benefits: Research has indicated that flavonoids like this one possess significant antioxidant properties, which can help in neutralizing free radicals in the body. This is crucial for maintaining overall health and may aid in disease prevention.
  • Anti-inflammatory Properties: Studies suggest that this compound exhibits anti-inflammatory effects, potentially alleviating symptoms related to chronic inflammatory conditions.
  • Potential Therapeutic Uses: Its unique structure allows for interactions with various biological targets, leading to investigations around its potential role in cancer prevention and treatment.
  • Chemical Structure: The chroman backbone, with hydroxyl groups in strategic positions, is significant for the compound’s reactivity and interaction with biological molecules.

In the words of renowned chemist Dr. Jane Goodhart, “Nature has provided us with a biological treasure trove of compounds that can inspire innovative therapeutic strategies.” This quote epitomizes the significance of compounds like 5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one in modern pharmacognosy and the ongoing quest to harness their potential for human health.

In conclusion, the exploration of this compound not only enriches our understanding of flavonoids but also opens doors to new avenues in clinical research and therapeutic applications.

Synonyms
naringenin
67604-48-2
5,7-Dihydroxy-2-(4-hydroxyphenyl)chroman-4-one
(+/-)-Naringenin
4',5,7-Trihydroxyflavanone
naringetol
93602-28-9
rac Naringenin
( inverted exclamation markA)-Naringenin
(-)-Naringenin
5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one
(+)-naringenin
CCRIS 8135
EINECS 266-769-1
MFCD00006844
CHEMBL32571
rac-Naringenin
MLS000028739
MLS000738094
CHEBI:50202
DTXSID50274239
5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one
NSC11855
NSC34875
(R,S)-Naringenin
SMR000059039
4',7-Trihydroxyflavanone
Flavanone,5,7-trihydroxy-
BE-14348A
4',5,7-trihydroxyflavan-4-one
Naringenin?
NSC-34875
4H-1-Benzopyran-4-one,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-
4H-1-Benzopyran-4-one,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-, (S)-
Naringenin (NAR)
Prestwick_531
(??)-Naringenin
Opera_ID_106
Prestwick0_000466
Prestwick1_000466
Prestwick2_000466
Prestwick3_000466
(R,S)-Naringenin 1000 microg/mL in Acetone
Oprea1_194140
SCHEMBL20571
BSPBio_000572
MLS001146907
5,7-Dihydroxy-2-(4-hydroxy-phenyl)-chroman-4-one
SPBio_002511
BPBio1_000630
MEGxp0_000358
SCHEMBL1934259
SCHEMBL25894738
ACon1_000582
BDBM19461
GTPL10298
DTXCID50196624
(+/-)-Naringenin, >=95%
HMS1569M14
HMS2096M14
HMS2231O18
HMS3352B08
HMS3373N07
HMS3656G15
Naringenin, natural (US), 98%
BCP31780
HY-W011641R
MFCD00870553
NSC815094
AKOS015895052
(+/-)-Naringenin, analytical standard
CS-W012357
FN01176
HY-W011641
KS-5142
NSC-815094
SB17305
(+/-)-Naringenin, ~95% (HPCE)
SMP1_000060
NCGC00017346-02
NCGC00017346-03
NCGC00017346-04
NCGC00017346-09
NCGC00095963-01
NCGC00095963-02
NCGC00095963-03
AC-20273
SY049933
SY075819
DB-057415
N0072
NS00003069
EN300-717813
S00279
AE-848/32605045
( inverted exclamation markA)-Naringenin (Standard)
BRD-A94669766-001-02-6
BRD-A94669766-001-04-2
Q57826857
Z1741982267
EC19096C-4404-4A16-9BF9-92F9F358E005
( )-Naringenin; 4?,5,7-Trihydroxyflavanone; H-1-benzopyran-4-one
5,7-Dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one, (S)- #
(+/-)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4- one
266-769-1