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Luteolin

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Identification
Molecular formula
C15H10O6
CAS number
491-70-3
IUPAC name
5,8-dihydroxy-2-phenyl-chromen-4-one
State
State

Luteolin is typically a solid at room temperature. It is found in many plants and contributes to the color of flowers and fruits.

Melting point (Celsius)
328.00
Melting point (Kelvin)
601.15
Boiling point (Celsius)
701.80
Boiling point (Kelvin)
974.95
General information
Molecular weight
286.24g/mol
Molar mass
286.2400g/mol
Density
1.6620g/cm3
Appearence

Luteolin is a yellow crystalline compound. It is part of the flavonoid group of polyphenolic compounds known for their diverse biological properties.

Comment on solubility

Solubility of 5,8-dihydroxy-2-phenyl-chromen-4-one

The solubility of the compound 5,8-dihydroxy-2-phenyl-chromen-4-one can be influenced by several factors, which can be nicely broken down into key considerations:

  • Polarity: The presence of hydroxyl (-OH) groups suggests that the compound may exhibit some degree of polarity, enhancing its ability to interact with polar solvents like water.
  • Hydrogen Bonding: The hydroxyl groups can form hydrogen bonds, which may lead to increased solubility in alcohols and other hydrogen bond-donating solvents.
  • Solvent Compatibility: This compound may be more soluble in organic solvents such as ethanol, acetone, or dimethyl sulfoxide (DMSO) due to the hydrophobic phenyl group, which can interact favorably with non-polar regions of these solvents.
  • Temperature Dependency: The solubility might increase with temperature, a common characteristic of many organic compounds, particularly when they have complex structures.

In summary, while specific solubility data for 5,8-dihydroxy-2-phenyl-chromen-4-one is not extensively documented, one can infer that its solubility profile is likely to be influenced by its molecular structure and the type of solvent used. This makes it essential to consider both the chemical nature and the test conditions when assessing its solubility.

Interesting facts

Interesting Facts About 5,8-Dihydroxy-2-phenyl-chromen-4-one

5,8-Dihydroxy-2-phenyl-chromen-4-one, commonly known as a flavonoid compound, is a fascinating entity in the realm of organic chemistry. This compound displays several intriguing properties and potential applications, which make it a subject of ongoing research.

Chemical Structure and Characteristics

  • The structure of this compound features a chromone backbone, which is noteworthy for its incorporation of a benzene ring.
  • Hydroxyl groups present at the 5 and 8 positions enhance its solubility and reactivity, leading to various biological activities.

Biological Significance

This flavonoid derivative has garnered attention for its potential health benefits, including:

  • Antioxidant Properties: It can scavenge free radicals, contributing to cellular protection against oxidative stress.
  • Anti-inflammatory Effects: Research suggests that this compound may help reduce inflammation, benefiting conditions such as arthritis.
  • Anticancer Activity: Preliminary studies indicate that it may inhibit the growth of certain cancer cells, making it a candidate for future cancer therapies.

Applications

Given its bioactivity, 5,8-dihydroxy-2-phenyl-chromen-4-one is explored in various fields including:

  • Pharmaceuticals: Potential applications in drug formulation due to its therapeutic properties.
  • Cosmetics: Inclusion in skincare products for its antioxidant benefits.
  • Food Industry: Used as a natural preservative and colorant due to its stability and appealing color profile.

Conclusion

With its impressive spectrum of biological activities and promising applications, 5,8-dihydroxy-2-phenyl-chromen-4-one stands as an exciting compound in both research and application. As scientists continue to explore its properties, this compound may pave the way for innovative solutions in health and industry.

Synonyms
Primetin
5,8-Dihydroxyflavone
5,8-dihydroxy-2-phenylchromen-4-one
5,8-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one
FLAVONE, 5,8-DIHYDROXY-
CHEBI:8410
DTXSID90203280
4H-1-Benzopyran-4-one, 5,8-dihydroxy-2-phenyl-
DTXCID90125771
4H-1-Benzopyran-4-one, 5,8-dihydroxy-2-phenyl-(9CI)
548-58-3
SCHEMBL4783697
LMPK12110098
AKOS015906549
NS00094842
Q27108070