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Testosterone

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Identification
Molecular formula
C19H28O2
CAS number
58-22-0
IUPAC name
(5R,17S)-17-hydroxy-10,13,17-trimethyl-2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-3-one
State
State

Testosterone is typically found in a solid state at room temperature. It is not very soluble in water but is soluble in alcohol and other organic solvents.

Melting point (Celsius)
153.00
Melting point (Kelvin)
426.15
Boiling point (Celsius)
413.00
Boiling point (Kelvin)
686.15
General information
Molecular weight
288.43g/mol
Molar mass
288.4290g/mol
Density
1.1450g/cm3
Appearence

Testosterone is a white to off-white crystalline powder. It may appear as small crystals or as a fine powder. It does not have a significant odor.

Comment on solubility

Solubility Characteristics

The compound (5R,17S)-17-hydroxy-10,13,17-trimethyl-2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyclopentaphenanthren-3-one presents unique solubility properties due to its complex molecular structure. Understanding the solubility of this compound is essential for its applications in various fields.

  • Polarity: The presence of hydroxyl groups can influence solubility in polar solvents such as water, whereas the hydrocarbon regions may favor solubility in non-polar solvents.
  • Hydrogen Bonding: The hydroxyl group present can engage in hydrogen bonding, enhancing interactions with other polar molecules.
  • Molecular Size: Its large and complex structure may impede solubility in aqueous solutions, potentially leading to limited solubility.

In general, the solubility of organic compounds such as this is often dictated by the balance between non-polar and polar characteristics:

  1. If the compound is more non-polar, it will be more soluble in non-polar solvents.
  2. Conversely, increased polarity from functional groups can lead to better solubility in polar solvents.

Ultimately, assessing the solubility of this compound requires careful consideration of environmental conditions and the solvent choice. In practical applications, it is often stated that “like dissolves like,” which indicates that the overall solubility behavior can greatly depend on the solvent system used.

Interesting facts

Interesting Facts about (5R,17S)-17-hydroxy-10,13,17-trimethyl-2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-3-one

This intriguing compound belongs to the class of steroids, which are vital in many biological processes. Here are some key points about this fascinating molecule:

  • Biological Significance: Compounds similar to this one play significant roles in various physiological functions, including hormone regulation and cell membrane stability.
  • Stereochemistry: The nomenclature (5R,17S) indicates the specific three-dimensional arrangement of atoms, which is crucial for the compound’s biological activity.
  • Applications in Medicine: Understanding the structure and function of such compounds can lead to advancements in pharmaceuticals, particularly in developing treatments for conditions linked to hormonal imbalances.
  • Structural Complexity: This compound's structure showcases an elaborate arrangement of multiple rings and functional groups, highlighting the diversity found within organic chemistry.
  • Synthetic Pathways: The synthesis of compounds like this one is a focus of research, as chemists seek efficient pathways for producing complex molecules with potential therapeutic effects.

As a chemistry student, studying such compounds illustrates the intricate balance between structure and function in biochemistry. The capacity of this compound to interact with biological targets is a reminder of the vast possibilities that organic chemistry offers in the field of medicinal research.

The study of steroids and similar structures not only deepens our understanding of biochemical processes but also opens doors for innovative solutions to health-related challenges. As one chemist succinctly put it, "Understanding the chemistry of life is the key to unlocking the development of future therapies."

Synonyms
5B-Androstan-3-on-17B-ol, 17A-methyl
WYZDXEKUWRCKOB-QLCSRNHCSA-N
17-.beta.-Hydroxy-17-.alpha.-methyl-5-.beta.-androstan-3-one