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Aminotetralinol

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Identification
Molecular formula
C11H15NO
CAS number
173814-63-6
IUPAC name
(5R,6S)-6-amino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-ol
State
State

The compound exists as a solid at room temperature, typically manifesting in crystalline forms.

Melting point (Celsius)
168.00
Melting point (Kelvin)
441.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
177.22g/mol
Molar mass
177.2160g/mol
Density
1.2300g/cm3
Appearence

Aminotetralinol typically appears as a white to off-white crystalline solid. The compound is usually finely powdered and has a crystalline texture. Its appearance might differ slightly depending on the purity and specific form (e.g., solvent content) of the sample, but it generally maintains its white to off-white coloration.

Comment on solubility

Solubility of (5R,6S)-6-amino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-ol

The solubility of (5R,6S)-6-amino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-ol in various solvents can be intriguing due to its complex structure. Here are several important factors to consider when evaluating its solubility:

  • Polarity: The overall polarity of the molecule greatly influences its solubility. Compounds with polar functional groups typically exhibit higher solubility in polar solvents such as water or methanol.
  • Hydrogen bonding: The presence of amino (-NH2) and hydroxyl (-OH) groups suggests the potential for hydrogen bonding, facilitating solubility in polar solvents.
  • Hydrophobic interactions: Part of the molecule's structure remains hydrophobic due to its aromatic content, which can hinder solubility in aqueous environments.

Based on these considerations, it can be expected that:

  1. The compound may exhibit better solubility in alcohols and other polar solvents.
  2. In water, the solubility could be limited due to the hydrophobic sections overshadowing the polar functionalities.
  3. Ultimately, precise solubility will depend on temperature, pH, and the presence of other solutes.

Understanding the solubility profile of such a compound is essential for applications in pharmaceuticals and chemical synthesis, as it can influence drug design and formulation significantly.

Interesting facts

Interesting Facts about (5R,6S)-6-amino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-ol

This fascinating compound belongs to the class of organic molecules known for their unique structural and functional properties. Here are some interesting insights:

  • Stereochemistry: The notation (5R,6S) indicates the stereochemical configuration at specific carbon centers. This aspect is vital for understanding the compound's reactivity and biological activity, as stereochemistry can significantly influence molecular interactions.
  • Pharmacological Potential: Compounds like (5R,6S)-6-amino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-ol may serve as significant pharmaceutical intermediates. The presence of the amino group can enhance its ability to interact with biological targets, making it a candidate for drug development.
  • Diverse Applications: This compound could find applications across various fields such as agriculture, medicinal chemistry, and even materials science. Its unique molecular structure allows for potential utilization in creating innovative materials or biological agents.
  • Uniqueness of Structure: The benzo[7]annulene moiety in this compound contributes to its distinctive electronic properties, which can be exploited in organic electronics and photonic applications due to the compound's conjugated system.

In conclusion, (5R,6S)-6-amino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-ol illustrates how intricate molecular designs can lead to various functional outcomes, highlighting the interconnectivity of chemistry and real-world applications.

Synonyms
BRN 5738849
5H-BENZOCYCLOHEPTEN-5-OL, 6,7,8,9-TETRAHYDRO-6-AMINO-, cis-
cis-6,7,8,9-Tetrahydro-6-amino-5H-benzocyclohepten-5-ol
cis-6-Amino-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-ol
DTXSID50177998
23445-16-1
RefChem:305321
DTXCID10100489