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Methadone

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Identification
Molecular formula
C21H27NO
CAS number
76-99-3
IUPAC name
(5S)-6-(dimethylamino)-5-methyl-4,4-diphenyl-hexan-3-one
State
State

At room temperature, Methadone typically exists as a solid in its hydrochloride salt form, which is the form used for medicinal purposes. As a base, it can exist as a liquid but is much less commonly encountered in that state.

Melting point (Celsius)
235.00
Melting point (Kelvin)
508.15
Boiling point (Celsius)
397.80
Boiling point (Kelvin)
670.95
General information
Molecular weight
309.45g/mol
Molar mass
309.4490g/mol
Density
1.0026g/cm3
Appearence

Appearance: Methadone is typically found as a white, crystalline powder. It is soluble in water and is often used in a hydrochloride form for medicinal purposes.

Comment on solubility

Solubility of (5S)-6-(dimethylamino)-5-methyl-4,4-diphenyl-hexan-3-one

The solubility of (5S)-6-(dimethylamino)-5-methyl-4,4-diphenyl-hexan-3-one in various solvents can significantly influence its applications in both laboratory and industrial settings. Understanding its solubility characteristics is crucial for effective use.

Key Points on Solubility:

  • Polar Solvents: This compound may exhibit limited solubility in polar solvents like water due to its non-polar and bulky aromatic structure.
  • Non-Polar Solvents: Conversely, it is likely to be more soluble in non-polar organic solvents such as hexane or toluene. This is attributed to its hydrophobic nature.
  • Temperature Dependence: Like many organic compounds, solubility can increase with temperature. Conducting experiments at elevated temperatures could enhance its dissolving capabilities.
  • pH Influence: The presence of the dimethylamino group might lead to variations in solubility depending on the pH. In acidic environments, it could protonate, potentially altering its solubility profile.

In summary, the solubility of (5S)-6-(dimethylamino)-5-methyl-4,4-diphenyl-hexan-3-one is dictated by a combination of its molecular structure and the properties of the solvent used. Exploring the solubility in both polar and non-polar environments will be crucial for attaining desired outcomes in practical applications.

Interesting facts

Interesting Facts about (5S)-6-(Dimethylamino)-5-methyl-4,4-diphenyl-hexan-3-one

(5S)-6-(Dimethylamino)-5-methyl-4,4-diphenyl-hexan-3-one, commonly known as a synthetic compound in organic chemistry, showcases a fascinating array of features and applications that intrigue both chemists and industry professionals alike.

Chemical Significance

This compound belongs to the category of ketones and is structurally characterized by:

  • Chirality: The presence of a chiral center in the molecule adds significant value in pharmaceuticals, especially in drug design where stereochemistry plays a crucial role.
  • Dimethylamino Group: The dimethylamino substituent is a common motif that enhances solubility and bioactivity, making it a vital component in many biologically active compounds.
  • Diphenyl Structure: The inclusion of diphenyl moieties contributes to unique electronic properties, potentially influencing the compound's reactivity and stability.

Applications

This compound is especially relevant in various fields, including:

  • Pharmaceuticals: It is often studied for its potential therapeutic effects, thanks to its structural characteristics that may mimic natural biological compounds.
  • Materials Science: Compounds with such structures can be utilized in developing advanced materials, including polymers and nanotechnology applications.
  • Organic Synthesis: As a versatile building block, it plays a critical role in developing other complex organic molecules.

Research and Development

Researchers continue to investigate this compound for:

  • Synthetic Pathways: Efficient routes of synthesis are a key area of study, targeting improved yields and reduced environmental impact.
  • Biochemical Pathways: Understanding the biological interactions and mechanisms can lead to novel therapeutic agents.
  • Toxicology and Safety: Assessing any potential toxic effects is crucial for ensuring safe applications in both industrial and pharmaceutical contexts.

In conclusion, (5S)-6-(dimethylamino)-5-methyl-4,4-diphenyl-hexan-3-one embodies a rich tapestry of properties and potential applications that highlight its importance in modern chemistry and beyond. As scientists continue to unravel its complexities, the possibilities for innovation and application remain boundless. The study of such compounds not only enriches our knowledge but also pushes the boundaries of what we can achieve in science and industry.

Synonyms
Levoisomethadone
Liden
(5S)-Isomethadone
l-Isomethadone
l-Isoamidone
561-10-4
(-)-Isomethadone
F16TLI77RN
ISOMETHADONE, (S)-
Isomethadone l-
RefChem:201465
Isomethadone l-form
(5S)-6-(dimethylamino)-5-methyl-4,4-diphenylhexan-3-one
(5S)?-?Isomethadone
UNII-F16TLI77RN
BRN 3211792
SCHEMBL24205
3-14-00-00281 (Beilstein Handbook Reference)
ISOMETHADONE, (-)-
CHEMBL352055
l-6-(Dimethylamino)-4,4-diphenyl-5-methyl-3-hexanone
ISOMETHADONE L-FORM [MI]
3-HEXANONE, 6-(DIMETHYLAMINO)-4,4-DIPHENYL-5-METHYL-, (S)-
Q27277501
(S)-6-(dimethylamino)-5-methyl-4,4-diphenylhexan-3-one
L-1-DIMETHYLAMINO-2-METHYL-3,3-DIPHENYL-4-HEXANONE
L-6-DIMETHYLAMINO-4,4-DIPHENYL-5-METHYL-3-HEXANONE
3-Hexanone, 6-(dimethylamino)-5-methyl-4,4-diphenyl-, (5S)-
3-HEXANONE, 6-(DIMETHYLAMINO)-5-METHYL-4,4-DIPHENYL-, (S)-