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Testosterone benzoate

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Identification
Molecular formula
C26H34O3
CAS number
5721-91-5
IUPAC name
[(5S,8R,9S,10S,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl] benzoate
State
State

At room temperature, testosterone benzoate is typically in a solid state. It is commonly used as an ester form of testosterone, a steroid hormone. The solid form ensures stability and ease of handling and storage.

Melting point (Celsius)
196.00
Melting point (Kelvin)
469.15
Boiling point (Celsius)
311.80
Boiling point (Kelvin)
584.95
General information
Molecular weight
414.59g/mol
Molar mass
414.5850g/mol
Density
1.1000g/cm3
Appearence

Testosterone benzoate appears as a white to off-white crystalline solid. It is often found in powder form and may be slightly hygroscopic, meaning it can absorb moisture from the air. The crystals may appear as small needle-like structures under magnification.

Comment on solubility

Solubility Overview

The compound [(5S,8R,9S,10S,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl] benzoate displays intriguing solubility characteristics that can be influenced by various factors.

Key Factors Affecting Solubility

1. **Polarity**: The presence of polar functional groups may enhance solubility in polar solvents. Conversely, larger hydrocarbon chains often increase non-polarity, making the compound less soluble in polar environments.

2. **Temperature**: As with many organic compounds, an increase in temperature typically improves solubility due to enhanced molecular movement, promoting dissolution.

3. **Solvent Type**: The choice of solvent is crucial. This compound is likely to dissolve better in non-polar solvents such as hexane or toluene rather than in polar solvents like water.

General Insights

  • In **water**, the compound's solubility is expected to be very low due to its hydrophobic regions.
  • It may exhibit moderate solubility in **organic solvents** due to its hydrophobic hydrocarbon structure.
  • Crystallization conditions can significantly affect solubility; thus, careful manipulation may lead to more favorable outcomes.

In conclusion, while the solubility of [(5S,8R,9S,10S,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl] benzoate is complex and solvent-dependent, understanding these factors can help predict its behavior in various environments. Always remember, "the more you know about a compound's structure, the better you can manipulate its solubility!"

Interesting facts

Interesting Facts about Benzoate of Tetradecahydrocyclopenta[a]phenanthren-17-yl

The compound commonly known as the benzoate of tetradecahydrocyclopentaphenanthren-17-yl is of particular interest in the field of organic chemistry, especially in the realms of pharmaceuticals and biochemistry. As a derivative of a steroid framework, it showcases a multitude of fascinating properties and applications.

Key Insights:

  • Steroidal Backbone: The structure of this compound includes a complex steroidal backbone, which plays a vital role in its biological activity.
  • Biological Activity: Compounds similar to benzoate derivatives are often studied for their hormonal effects, including potential applications in treating hormone-related conditions.
  • Analytical Techniques: Its unique structure makes it an interesting subject for various analytical techniques, such as NMR and mass spectrometry, aiding chemists in structure elucidation.
  • Synthetic Pathways: The synthesis of this compound involves advanced organic reactions that demonstrate the artistry and precision needed in modern organic synthesis.

Furthermore, exploring the interactions of this compound with other biological molecules can lead to insights into its pharmacokinetics and mechanisms of action. As noted in research, "Understanding the behavior of such complex molecules opens pathways to novel therapeutic designs." The continued study of this benzoate is essential for contributing to a broader understanding of synthetic steroids and their potential applications in modern medicine.

Overall, this compound stands as a testament to the intricate interplay of structure and function in chemistry, showcasing how small modifications in molecular architecture can lead to significant changes in biological activity.

Synonyms
Stanolone benzoate
1057-07-4
Dihydrotestosterone benzoate
Hermalone
Sarcosan
Androstanolone benzoate
5alpha-Dihydrotestosterone benzoate
NSC 69549
Vetranal
5-alpha-Dihydrotestosterone benzoate
EINECS 213-891-8
BRN 3122672
NSC-69549
T74307G2D9
(5-alpha,17-beta)-17-(Benzoyloxy)androstan-3-one
5.alpha.-Androstan-3-one, 17.beta.-hydroxy-, benzoate
DTXSID0036502
4-09-00-00464 (Beilstein Handbook Reference)
5alpha-Androstan-3-one, 17beta-hydroxy-, benzoate
Androstan-3-one, 17-(benzoyloxy)-, (5alpha,17beta)-
Androstan-3-one, 17-(benzoyloxy)-, (5-alpha,17-beta)-
5-alpha-ANDROSTAN-3-ONE, 17-beta-HYDROXY-, BENZOATE
DTXCID8016502
5alpha-Androstan-3-one, 17beta-hydroxy-, benzoate (8CI)
Androstan-3-one, 17-(benzoyloxy)-, (5alpha,17beta)-(9CI)
Androstan-3-one, 17-(benzoyloxy)-, (5-alpha,17-beta)-(9CI)
Androstanolone 17-benzoate
[(5S,8R,9S,10S,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl] benzoate
5.alpha.-Dihydrotestosterone benzoate
Androstanolone benzoate;Dihydrotestosterone benzoate;DHTB
UNII-T74307G2D9
5-alpha-17-beta-Hydroxyandrostan-3-one benzoate
SCHEMBL3366936
CHEBI:34979
ZGDZDAPCWHIIKB-LVYWIKMTSA-N
Androstan-3-one, 17-(benzoyloxy)-, (5.alpha.,17.beta.)-
NSC69549
5.alpha.-Androstan-3-one, benzoate
AKOS015889514
DA-50465
PD126040
5alpha-Androstan-17beta-ol-3-one benzoate
HY-128698
CS-0098596
NS00023387
(5.alpha.,17.beta.)-3-Oxoandrostan-17-yl benzoate
Q27116348
Androstanolone 17-benzoate, VETRANAL(TM), analytical standard