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Ciclosporin

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Identification
Molecular formula
C62H111N11O12
CAS number
59865-13-3
IUPAC name
6-(1-ethylindol-3-yl)-9-(6-oxooctyl)-3-sec-butyl-1,4,7,10-tetrazabicyclo[10.4.0]hexadecane-2,5,8,11-tetrone
State
State

At room temperature, cyclosporine is a solid. However, in its pharmaceutical formulations, it may be prepared as a suspension or solution.

Melting point (Celsius)
148.00
Melting point (Kelvin)
421.15
Boiling point (Celsius)
754.00
Boiling point (Kelvin)
1 027.15
General information
Molecular weight
1202.61g/mol
Molar mass
1 202.6100g/mol
Density
1.0620g/cm3
Appearence

Cyclosporine, a key immunosuppressant, typically appears as a white or off-white powder. In pharmaceutical preparations, it can be found in liquid, capsule, or injection forms, varying slightly in appearance depending on its formulation. These forms are generally designed for ease of administration and are tailored for stability and bioavailability.

Comment on solubility

Solubility of 6-(1-ethylindol-3-yl)-9-(6-oxooctyl)-3-sec-butyl-1,4,7,10-tetrazabicyclo[10.4.0]hexadecane-2,5,8,11-tetrone (C62H111N11O12)

The solubility of a compound like 6-(1-ethylindol-3-yl)-9-(6-oxooctyl)-3-sec-butyl-1,4,7,10-tetrazabicyclo[10.4.0]hexadecane-2,5,8,11-tetrone can often be influenced by several factors, including its molecular structure and functional groups.

Key Factors Affecting Solubility:

  • Polarity: Compounds with polar functional groups tend to dissolve well in polar solvents, while non-polar compounds are generally soluble in non-polar solvents.
  • Molecular Size: Larger molecules may face steric hindrance that can affect solubility in different solvents.
  • Hydrogen Bonding: The ability to form hydrogen bonds can enhance solubility in water and other polar solvents.

The specific structure of this compound suggests that it may exhibit varied solubility characteristics:

  • Its large hydrophobic regions could limit solubility in water, yet enhance solubility in organic solvents.
  • The presence of nitrogen atoms may suggest potential for hydrogen bonding, which could interface positively with polar solvents such as alcohols.

In summary, while predicting the solubility of such a complex compound can be challenging, understanding the interplay of its structural characteristics allows for informed expectations regarding its solubility profile in various environments. Further experimental validation would be essential to determine the practical solubility and behavior of this unique compound in real-world applications.

Interesting facts

Interesting Facts about 6-(1-ethylindol-3-yl)-9-(6-oxooctyl)-3-sec-butyl-1,4,7,10-tetrazabicyclo[10.4.0]hexadecane-2,5,8,11-tetrone

This compound holds a unique place in the field of organic chemistry, particularly due to its complex structure and fascinating properties:

  • Structural Diversity: The compound features a diverse array of functional groups, including1 indole and sec-butyl, which contribute to its potential reactivity and interactions in various chemical environments.
  • Tetrazabicyclic Framework: With its bicyclic structure, it is a member of the tetrazabicyclo family. This structural characteristic is particularly intriguing as it may facilitate unique chemical behaviors, such as electron transfer and catalytic activity.
  • Potential Applications: Researchers are studying its possible applications in fields such as drug design and material science. The combination of indole and tetrazine rings suggests a potential for biological activity and utility as a scaffold for drug development.
  • Complex Synthesis: The synthesis of this compound can be quite challenging and may require multiple steps, highlighting the complexities of organic synthesis techniques used by chemists.
  • Biological Activity: Compounds with indole moieties are known for a wide range of biological activities. The presence of this structure may imply potential therapeutic properties worth exploring.
  • Exploration Opportunities: There's ongoing research to explore the compound’s interactions with various biomolecules, which could lead to significant discoveries in medicinal chemistry.

The compound is a testament to the intricacies found in organic compounds, illustrating how subtle variations in structure can lead to vast differences in properties and potential applications. As scientists delve deeper into understanding its unique characteristics, we can anticipate emerging exciting developments in the near future.