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6-(1-piperidyl)-7H-dibenzo[b,e][1,4]diazepine

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Identification
Molecular formula
C16H18N4
IUPAC name
6-(1-piperidyl)-7H-benzo[d][1,3]benzodiazepine
State
State

The compound is usually found as a solid at room temperature.

Melting point (Celsius)
208.00
Melting point (Kelvin)
481.15
Boiling point (Celsius)
382.80
Boiling point (Kelvin)
655.95
General information
Molecular weight
262.34g/mol
Molar mass
262.3370g/mol
Density
1.1300g/cm3
Appearence

This compound is typically a white to off-white crystalline solid. It may appear as a powder or in crystalline form depending on the specific preparation and handling.

Comment on solubility

Solubility of 6-(1-piperidyl)-7H-benzo[d][1,3]benzodiazepine

The solubility of 6-(1-piperidyl)-7H-benzo[d][1,3]benzodiazepine is an important aspect to consider, particularly when assessing its applications in pharmaceuticals. This compound exhibits a range of solubility characteristics that can influence its bioavailability and therapeutic effectiveness.

Key Points on Solubility:

  • Solvent Interaction: The solubility is dependent on the polarity of the solvent used. Generally, organic solvents such as dimethyl sulfoxide (DMSO) or methanol are more effective in dissolving this compound compared to water.
  • Temperature Effects: Increasing the temperature can enhance solubility by promoting molecular movement and breaking intermolecular interactions.
  • pH Levels: The solubility may also vary with pH; the presence of acidic or basic conditions can alter the ionization of the compound, thus affecting its solubility.
  • Solid Form: The crystallinity of the compound plays a crucial role; amorphous forms typically exhibit higher solubility than their crystalline counterparts due to increased surface area.

It is essential to consider these factors during formulation development to optimize the use of 6-(1-piperidyl)-7H-benzo[d][1,3]benzodiazepine in various applications. Understanding its solubility behavior can significantly impact its effectiveness and formulation strategies.

Interesting facts

Interesting Facts about 6-(1-piperidyl)-7H-benzo[d][1,3]benzodiazepine

6-(1-piperidyl)-7H-benzo[d][1,3]benzodiazepine is a fascinating chemical compound that belongs to the class of benzodiazepines, which are well-known for their usage in therapeutics and pharmacology. Here are some intriguing aspects of this compound:

  • Mechanism of Action: As a benzodiazepine, this compound typically interacts with the GABAA receptor in the brain, enhancing the inhibitory effect of GABA, a neurotransmitter. This interaction leads to a calming effect on the central nervous system.
  • Potential Therapeutic Uses: Compounds in this class may be explored for their applications in treating anxiety, insomnia, and various disorders associated with neurotransmitter imbalances.
  • Structural Complexity: The unique structure of 6-(1-piperidyl)-7H-benzo[d][1,3]benzodiazepine, featuring a piperidine group, contributes to its pharmacological properties. The presence of these functional groups allows for specific interactions with various biological targets.
  • Scientific Interest: Researchers are continually studying this compound to expand our understanding of benzodiazepines and discover new derivatives that may have improved efficacy or reduced side effects.
  • Safety Profile: Like other benzodiazepines, this compound may have risks associated with dependence and withdrawal. Understanding these aspects is crucial for ongoing research and clinical applications.

In summary, 6-(1-piperidyl)-7H-benzo[d][1,3]benzodiazepine exemplifies the intricate relationship between structure and function in pharmacology. As research continues to unveil its potential, it remains a significant subject of interest for both scientists and healthcare practitioners alike.

Synonyms
BRN 0664740
5H-DIBENZO(d,f)(1,3)DIAZEPINE, 6-PIPERIDINO-
6-Piperidino-5H-dibenzo(d,f)(1,3)diazepine
DTXSID60182715
2849-01-6
DTXCID00105206
5-25-11-00362 (beilstein handbook reference)