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Cefaclor

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Identification
Molecular formula
C15H14ClN3O4S
CAS number
70356-03-5
IUPAC name
6-[[2-[(4-ethyl-2,3-dioxo-piperazine-1-carbonyl)amino]-2-phenyl-acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
State
State
Cefaclor is commonly in the solid state at room temperature, typically marketed as a dry powder for reconstitution or as capsules.
Melting point (Celsius)
164.00
Melting point (Kelvin)
437.15
Boiling point (Celsius)
199.00
Boiling point (Kelvin)
472.15
General information
Molecular weight
367.81g/mol
Molar mass
367.8060g/mol
Density
1.4900g/cm3
Appearence
Cefaclor usually appears as a white or slightly yellowish, crystalline powder.
Comment on solubility

Solubility of 6-[[2-[(4-ethyl-2,3-dioxo-piperazine-1-carbonyl)amino]-2-phenyl-acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid (C15H14ClN3O4S)

The solubility of chemical compounds can greatly influence their applicability in various fields, particularly in pharmaceuticals and biochemistry. For the compound in question, solubility characteristics are critical for understanding its behavior in biological systems. Here are the key points regarding its solubility:

  • Solvent Dependence: This compound's solubility is likely influenced by the polarity of the solvent used. Hence, it may exhibit better solubility in polar solvents compared to non-polar ones.
  • Functional Groups: The presence of various functional groups such as carboxylic acids and amines can enhance intermolecular interactions with solvents, contributing to increased solubility.
  • pH Sensitivity: Being a compound that contains a carboxylic acid moiety, its solubility may also depend on the pH of the solution, as it can exist in ionized forms at higher pH levels.
  • Temperature Effects: A typical feature of many compounds is that solubility can increase with temperature; thus, heating the solution may potentially improve solubility.

Overall, it can be summarized that solubility is a multifaceted property influenced by numerous factors. As a rule, understanding these properties is essential for optimizing the use of this compound in practical applications.

Interesting facts

Interesting Facts about 6-[[2-[(4-ethyl-2,3-dioxo-piperazine-1-carbonyl)amino]-2-phenyl-acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

This compound is a fascinating example of complex chemical architecture commonly found in bioactive molecules. Its structure illustrates a blend of various functional groups that contribute to its biological activity, particularly in medicinal chemistry.

Structural Diversity

  • Bicyclic Structure: The compound features a bicyclic system that is characteristic of many pharmaceutical agents, aiding in the enhancement of bioavailability.
  • Piperazine Ring: The included piperazine moiety is often associated with antidepressant and antipsychotic medications, showcasing its crucial role in medicinal applications.
  • Thia and Oxo Groups: The presence of sulfur in the thia group and carbonyls adds to the reactivity and potential pharmacological properties of the compound.

Biological Significance

Compounds with intricate structures like this one are often examined for their potential therapeutic uses. Notably:

  • The structural motifs may interact with various biological targets including enzymes and receptors.
  • It may possess antimicrobial or antifungal properties due to the combination of ketone and carboxylic acid functionalities.

Research Potential

Scientists are constantly on the lookout for compounds that can lead to new drug discoveries. The unique combination of its substituents shows promise for further modification or optimization in the quest for:

  • Enhanced Selectivity: Tailoring interactions with specific biological targets.
  • Reduced Side Effects: Improving the safety profile of existing therapies.

"The most exciting chemistry often lies at the intersection of synthesis and biological discovery."

In conclusion, 6-[[2-[(4-ethyl-2,3-dioxo-piperazine-1-carbonyl)amino]-2-phenyl-acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid exemplifies the rich potential contained in complex organic compounds. Its unique structure begs for deeper investigation, driving the science of drug discovery forward.

Synonyms
SCHEMBL4486297
CHEMBL1616926
BCP13727
STK397060
AKOS005434036
498531-49-0
DB-017799
(2S,5R,6R)-6-[[(2R)-2-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid monohydrate
EN300-27694695
6-{[{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}(phenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
6-{2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-phenylacetamido}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid