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Thienamycin

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Identification
Molecular formula
C12H23N3O6S
CAS number
59942-63-1
IUPAC name
[6-[2-acetoxy-1-[[(2S)-1-methyl-4-propyl-pyrrolidine-2-carbonyl]amino]propyl]-4,5-dihydroxy-2-methylsulfanyl-tetrahydropyran-3-yl] acetate
State
State

At room temperature, Thienamycin is typically in a solid crystalline form.

Melting point (Celsius)
205.00
Melting point (Kelvin)
478.15
Boiling point (Celsius)
200.00
Boiling point (Kelvin)
473.15
General information
Molecular weight
337.42g/mol
Molar mass
337.4150g/mol
Density
1.5000g/cm3
Appearence

Thienamycin is a colorless solid that is usually seen in its crystalline form. When pure, it can appear as a white powder or crystals.

Comment on solubility

Solubility of 6-[2-acetoxy-1-[[(2S)-1-methyl-4-propyl-pyrrolidine-2-carbonyl]amino]propyl]-4,5-dihydroxy-2-methylsulfanyl-tetrahydropyran-3-yl acetate

The solubility of this complex compound is influenced by various factors, including its molecular structure and the presence of functional groups. Understanding its solubility characteristics is crucial for applications in pharmaceuticals and chemical research. Here are some key points about its solubility:

  • Polarity: The presence of multiple hydroxyl groups (-OH) and the acetoxy group (-OCOCH3) suggests that the compound may exhibit hydrophilic properties, potentially enhancing its solubility in polar solvents like water.
  • Hydrophobic regions: The hydrophobic tail consisting of the propyl and pyrrolidine groups may lead to reduced solubility in aqueous environments, indicating that the compound could have better solubility in organic solvents such as ethanol or DMSO.
  • Functional groups: The interaction of the acetoxy and hydroxyl groups with water molecules can create strong hydrogen bonds, which may further influence the solubility behavior.
  • Temperature effect: As with many compounds, an increase in temperature generally increases solubility, potentially allowing the compound to dissolve more readily in solvents.

In summary, while this compound may have good solubility in polar organic solvents due to its functional groups, its solubility in water could be moderate or low due to the hydrophobic regions. Understanding these properties can help predict behavior in various formulations and applications.

Interesting facts

Interesting Facts about the Compound: 6-[2-acetoxy-1-[[(2S)-1-methyl-4-propyl-pyrrolidine-2-carbonyl]amino]propyl]-4,5-dihydroxy-2-methylsulfanyl-tetrahydropyran-3-yl] acetate

This complex chemical compound features a unique combination of functional groups that contribute to its potential biological activities. Here are some intriguing aspects about this compound:

  • Structure Complexity: The compound contains multiple rings and functional groups, including a tetrahydropyran ring and a pyrrolidine moiety, indicating its potential complexity in activity and mechanism.
  • Biological Relevance: Many compounds with such intricate structures exhibit a range of pharmacological activities, including interactions with proteins and enzymes within biological systems.
  • Potential Applications: Given its structure, this compound may hold promise in medicinal chemistry, possibly serving as a lead compound for the development of new therapeutic agents.
  • Chirality: The presence of chiral centers in the pyrrolidine component suggests stereoselective properties, which can lead to different biological activities depending on the 3D orientation of the compound.

As chemists study such compounds, they often highlight that the nuances in their structure can lead to profound implications in drug design. Indeed, as noted in the field, "A small change in structure can lead to a large change in function." This assertion emphasizes the importance of understanding each component of structural complexity.

The exploration of compounds like this not only enhances our comprehension of organic molecules but also opens doors to innovative solutions in tackling various health-related issues. The synthesis and study of such intricate molecules exemplify the intricate dance of chemistry in pursuing new horizons in science.