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Cloxacillin

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Identification
Molecular formula
C19H17ClN3O5S
CAS number
61-72-3
IUPAC name
6-[(2-allylsulfanylacetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
State
State
Cloxacillin is typically a solid at room temperature, most commonly prepared as its sodium salt for oral or intravenous administration in medical contexts.
Melting point (Celsius)
179.90
Melting point (Kelvin)
453.10
Boiling point (Celsius)
397.90
Boiling point (Kelvin)
671.00
General information
Molecular weight
435.89g/mol
Molar mass
435.8940g/mol
Density
1.4405g/cm3
Appearence

Cloxacillin typically appears as a white to off-white crystalline powder. It is commonly provided in the form of its sodium salt for pharmaceutical use, which also maintains a similar appearance.

Comment on solubility

Solubility of 6-[(2-allylsulfanylacetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

The solubility of 6-[(2-allylsulfanylacetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid can be influenced by various factors such as its molecular structure, the presence of functional groups, and temperature conditions. Overall, an understanding of its solubility is essential for its practical applications.

Key Points on Solubility:

  • Polar vs. Non-Polar Characteristics: The presence of polar functional groups, such as carboxylic acids and sulfur atoms, suggests that this compound may exhibit higher solubility in polar solvents.
  • Solvent Compatibility: It is likely to be soluble in solvents like water and alcohols, which can effectively interact with its polar regions.
  • Temperature Relevance: Generally, an increase in temperature can enhance the solubility of most compounds, and this may also apply to this bicyclic compound.

In conclusion, due to its complex structure and specific functional groups, the solubility profile of 6-[(2-allylsulfanylacetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid is potentially favorable in polar environments, but empirical testing in various solvents will provide the most accurate information regarding its solubility characteristics.

Interesting facts

Interesting Facts about 6-[(2-allylsulfanylacetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

This compound, which we can refer to as a member of the thiazolidinone class, exhibits unique structural properties that contribute to its potential applications in medicinal chemistry.

Structure and Features

The compound is characterized by:

  • Multicyclic Framework: Its bicyclic structure provides rigidity and can influence biological activity.
  • Sulfanyl Group: The presence of a sulfenyl moiety enhances its reactivity, potentially allowing for interesting interactions with biological targets.
  • Amino Acid Derivative: The incorporation of an aminocarboxylic acid suggests potential similarities to natural products, which can be advantageous for drug design.

Biological Significance

Compounds of this nature have garnered attention in research due to their:

  • Antimicrobial Properties: Many thiazolidinones are explored for their ability to combat bacterial infections.
  • Anti-inflammatory Activity: They may possess properties that help modulate inflammatory responses.
  • Potential in Cancer Therapy: Some analogs have shown promise in inhibiting cancer cell proliferation.

Research and Applications

Ongoing studies are investigating:

  • Synthetic Pathways: Various methods for synthesizing this compound, paving the way for further derivatives.
  • Mechanisms of Action: Understanding how this structure interacts with biological systems can lead to more effective therapies.
  • Drug Development: The exploration of its pharmacokinetics and toxicity to maximize therapeutic potential.

In summary, 6-[(2-allylsulfanylacetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid exemplifies the intriguing intersection of chemistry and pharmacology, offering insights into the development of novel therapeutics. Researchers are excited about the potential this compound may hold in various fields, especially in the fight against resistant infections and chronic diseases.

Synonyms
DTXSID20861670
3,3-Dimethyl-7-oxo-6-{2-[(prop-2-en-1-yl)sulfanyl]acetamido}-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid