Skip to main content

Methylene Blue

ADVERTISEMENT
Identification
Molecular formula
C16H18N3ClS
CAS number
61-73-4
IUPAC name
6-[2-(diethylamino)ethoxy]-N,N-dimethyl-1,3-benzothiazol-2-amine
State
State
Methylene Blue is usually encountered in a solid crystalline state at room temperature. It is soluble in water and ethanol, where it forms a vivid blue solution.
Melting point (Celsius)
100.00
Melting point (Kelvin)
373.00
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.00
General information
Molecular weight
319.85g/mol
Molar mass
319.8520g/mol
Density
1.2000g/cm3
Appearence

Methylene Blue appears as a dark green crystalline powder, which gives a deep blue solution when dissolved in water. It can also appear in a crystalline form, showing a metallic luster. When diluted in water, it exhibits a vibrant blue color which is characteristic of this compound.

Comment on solubility

Solubility of 6-[2-(diethylamino)ethoxy]-N,N-dimethyl-1,3-benzothiazol-2-amine

The solubility of 6-[2-(diethylamino)ethoxy]-N,N-dimethyl-1,3-benzothiazol-2-amine is influenced by several factors, predominantly its molecular structure. This compound, which contains both aromatic and aliphatic components, demonstrates a complex solubility profile. Here are some key points to consider:

  • Polarity: The presence of the diethylamino group introduces significant polarity, likely enhancing solubility in polar solvents such as water. This characteristic can be pivotal, making the compound capable of interacting favorably with its solvent environment.
  • Hydrophobic Regions: The benzothiazole moiety is more hydrophobic, which might limit solubility in overly polar solvents. This creates a scenario where the compound may show differing solubility based on the solvent's nature.
  • Solvent Dependency: Solubility can vary dramatically in different organic solvents. For instance, it is expected to be more soluble in solvents like ethanol or DMSO, which can accommodate both polar and nonpolar characteristics.
  • Temperature Effect: As with many organic compounds, increasing temperature can enhance solubility, making it important to consider environmental conditions when evaluating solubility.

In summary, while 6-[2-(diethylamino)ethoxy]-N,N-dimethyl-1,3-benzothiazol-2-amine can dissolve well in specific solvents, its solubility is multifaceted and dependent on factors such as polarity, temperature, and solvent type. These elements underscore the importance of context in solubility studies, ultimately affecting the compound’s practical applications.

Interesting facts

Interesting Facts about 6-[2-(Diethylamino)ethoxy]-N,N-dimethyl-1,3-benzothiazol-2-amine

6-[2-(Diethylamino)ethoxy]-N,N-dimethyl-1,3-benzothiazol-2-amine is a fascinating compound that belongs to a class of chemicals known for their varied applications in the field of medicinal chemistry. This compound showcases the intriguing intersection of heterocycles and amines, making it a noteworthy subject of study. Below are some engaging insights into its properties and significance:

  • Versatile Applications: Compounds featuring a benzothiazole core have been extensively researched for their roles in pharmaceuticals, particularly as anticancer and antimicrobial agents. This compound may present similar potential.

  • Structure-Activity Relationship (SAR): The unique arrangement of functional groups in this compound, particularly the diethylamino and dimethyl groups, may enhance its biological activity. Understanding how variations in the structure affect efficacy can help in drug design.

  • Heterocyclic Chemistry: The inclusion of a benzothiazole moiety represents a rich area of heterocyclic chemistry, where the presence of nitrogen and sulfur in the ring can lead to unique reactivity patterns and properties.

  • Research Significance: Ongoing studies often investigate how this compound interacts with biological targets, paving the way for advancements in various therapeutic areas.

  • Potential Challenges: Despite its promising features, compounds like this may face challenges regarding their pharmacokinetics, stability, and toxicity, which are critical factors in drug development.

In conclusion, 6-[2-(Diethylamino)ethoxy]-N,N-dimethyl-1,3-benzothiazol-2-amine exemplifies the complexities and potential of organic compounds in medicinal chemistry. As scientists continue to explore its applications, this compound stands as a testament to the intricate relationship between molecular structure and biological activity.

Synonyms
Diamthazole
Dimazole
95-27-2
Asterol
Dimazol
Diamethazole
Dimazole [INN]
Dimazolo
Dimazolum
6-[2-(Diethylamino)ethoxy]-N,N-dimethyl-1,3-benzothiazol-2-amine
Dimazolo [DCIT]
Dimazolum [INN-Latin]
Diamthazole [INN:BAN]
2KL01R8ZV1
Dimazol [INN-Spanish, French]
DTXSID1046182
EINECS 202-406-5
7162-33-6
DIMAZOLE [WHO-DD]
6-(2-Diethylaminoethoxy)-2-dimethylaminobenzothiazol
6-(2-Diethylaminoethoxy)-2-dimethylaminobenzothiazole
DTXCID9026182
2-Benzothiazolamine, 6-(2-(diethylamino)ethoxy)-N,N-dimethyl-
2-Benzothiazolamine, 6-[2-(diethylamino)ethoxy]-N,N-dimethyl-
Benzothiazole, 6-(2-diethyl-aminoethoxy)-2-dimethylamino-
NCGC00160485-01
Dimazolum (INN-Latin)
Asterol (TN)
Dimazol (INN-Spanish, French)
6-(2-Diethylaminoethylaminoethoxy)-2-dimethylaminobenzothiazole
UNII-2KL01R8ZV1
6-(2-(diethylamino)ethoxy)-N,N-dimethyl-1,3-benzothiazol-2-amine
6-(2-diethylaminoethyloxy)-N,N-dimethyl-1,3-benzothiazol-2-amine
ChemDiv3_000221
Mycotol R0-2-2453
Oprea1_308992
Oprea1_588999
SCHEMBL467444
CHEMBL1184360
CHEBI:103934
HMS1473K01
6-(2-(diethylamino)ethoxy)-N,N-dimethylbenzo[d]thiazol-2-amine
Tox21_111847
STK525110
AKOS001483000
CCG-103023
DB13858
CAS-95-27-2
IDI1_019539
NCGC00160485-02
DA-62837
HY-148160
CS-0613910
NS00040442
SBI-0653912.0001
EN300-18560030
Q5277172
BRD-K03978601-300-01-6
6-[2-(Diethylamino)ethoxy]-N,N-dimethyl-1,3-benzothiazol-2-amine #
202-406-5