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Cefotetan

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Identification
Molecular formula
C17H17N3O8S1
CAS number
69712-56-7
IUPAC name
6-[(2-ethoxy-1-naphthyl)carbamoyl]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
State
State

At room temperature, Cefotetan is a solid.

Melting point (Celsius)
152.00
Melting point (Kelvin)
425.00
Boiling point (Celsius)
275.00
Boiling point (Kelvin)
548.00
General information
Molecular weight
576.62g/mol
Molar mass
576.6190g/mol
Density
1.6800g/cm3
Appearence

Cefotetan typically appears as a white to pale yellow crystalline powder. It may vary slightly in color depending on the manufacturing process and purity.

Comment on solubility

Solubility of 6-[(2-ethoxy-1-naphthyl)carbamoyl]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid (C17H17N3O8S1)

The solubility of 6-[(2-ethoxy-1-naphthyl)carbamoyl]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid is influenced by several factors, including its molecular structure and functional groups. Here are some key points to consider:

  • Polarity: The presence of polar functional groups such as carboxylic acid and amide can enhance solubility in polar solvents like water.
  • Hydrophobic interactions: Conversely, the hydrophobic character imparted by the naphthyl ring and ethoxy group may reduce solubility in water, suggesting a preference for organic solvents.
  • pH effect: The solubility of this compound may vary with pH. In an acidic environment, the carboxylic acid group could remain protonated, affecting overall solubility comparably in alkaline solutions, where it could ionize.
  • Solvent effects: Common solvents for this compound may include dimethyl sulfoxide (DMSO) and ethanol, which can enhance its solubility compared to water.

In summary, the solubility of this complex bicyclic compound is a balance between its polar and nonpolar characteristics. Its unique chemical structure results in a solubility profile that may require specific solvents to achieve desired concentrations for practical applications. Understanding these nuances is critical for both synthesis and formulation in various chemical contexts.

Interesting facts

Interesting Facts about 6-[(2-ethoxy-1-naphthyl)carbamoyl]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

This compound, with its complex structure, showcases a fascinating relationship between organic chemistry and pharmacology. One of the most intriguing aspects of this compound lies in its potential applications. Scientists are exploring its role as a novel therapeutic agent, particularly in the field of antimicrobial development. Here are some captivating points about this compound:

  • Multifaceted Structure: The structure features a unique bicyclic system that incorporates sulfur, which can impart specific reactivity patterns and biological activity.
  • Potential Therapeutic Uses: Researchers are investigating its efficacy in treating infections, given its antibacterial properties attributed to the thia-azabicyclo framework.
  • Ethoxy-Substituted Naphthalene: The naphthyl group not only contributes to its structural complexity but may also enhance lipophilicity, influencing the compound's interaction with biological membranes.
  • Carbamoyl Group: This functional group can play a critical role in influencing the pharmacokinetics of the compound, making it a focus for drug design strategies.

"Chemical innovation often lies within the subtleties of molecular structure." This compound is a prime example of how small changes in molecular architecture can lead to diverse biological effects. It's essential for aspiring chemists to delve into such compounds as they point towards the future of medicinal chemistry. As synthetic methods advance, the exploration of similar compounds like this one can unveil new avenues in drug discovery.

The journey of understanding this compound is not merely academic; it opens doors to exploring novel therapeutic strategies and enhances our comprehension of molecular interactions in biological systems.