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Cefalotin

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Identification
Molecular formula
C16H16N2O4S
CAS number
153-61-7
IUPAC name
6-[(2-ethoxynaphthalene-1-carbonyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
State
State

Cefalotin sodium is typically found as a solid crystalline powder at room temperature. It is not stable in solution for prolonged periods and must be dissolved in a suitable solvent shortly before administration when used in clinical settings.

Melting point (Celsius)
0.00
Melting point (Kelvin)
0.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
396.42g/mol
Molar mass
396.4150g/mol
Density
1.4600g/cm3
Appearence

Cefalotin sodium appears as a white to off-white crystalline powder that is hygroscopic (i.e., it attracts moisture from the air). It is usually supplied in vials as a sterile powder for reconstitution before use.

Comment on solubility

Solubility of 6-[(2-ethoxynaphthalene-1-carbonyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

The solubility of the compound 6-[(2-ethoxynaphthalene-1-carbonyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid can be influenced by various factors. Understanding these factors can help predict its behavior in different environments:

  • Polarity: The presence of polar functional groups, such as carboxylic acids, may enhance solubility in polar solvents like water.
  • Hydrophobic character: The ethoxynaphthalene moiety introduces a hydrophobic region that might limit solubility in aqueous solutions.
  • pH variations: The solubility can be affected by pH, particularly due to the carboxylic acid group, which can ionize depending on the environmental pH.
  • Temperature: Generally, an increase in temperature can lead to increased solubility for many organic compounds, though exceptions exist.

Overall, the solubility of this compound may be variable, showing better dissolution in organic solvents compared to water. Its structural complexity likely contributes to its solubility characteristics, making it essential to evaluate specific conditions for optimal usage.

Interesting facts

Interesting Facts about 6-[(2-ethoxynaphthalene-1-carbonyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

This intriguing compound has garnered attention due to its unique structure and potential applications in various fields of science, particularly within medicinal chemistry. Here's what makes this compound particularly fascinating:

  • Unique Structural Characteristics: The compound features a bicyclic structure, which is notable for comprising both thioether and amide functionalities. This unique arrangement enhances its chemical reactivity and biological potency.
  • Potential Pharmacological Uses: Compounds with similar structures have been explored for their potential therapeutic effects, such as in the treatment of bacterial infections or as anti-cancer agents. The incorporation of a naphthalene moiety may influence biological activity, opening avenues for further research.
  • Derivative Synthesis: The versatility of the compound’s structure allows for various derivatives to be synthesized, which can be tailored to optimize desired properties. For instance, modifications can enhance solubility or alter biological activity.
  • Interdisciplinary Appeal: Scientists from different fields—organic chemistry, pharmacology, and materials science—may find interest in this compound due to its multifunctional character. This broadens collaborative opportunities and fosters innovation in research.
  • Synthesis Challenges: The synthesis of such complex molecules poses significant challenges, often requiring advanced techniques in organic synthesis. These challenges can lead to novel methodologies that are of interest to synthetic chemists.

In summary, 6-[(2-ethoxynaphthalene-1-carbonyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid stands at the intersection of structural elegance and functional potential, making it a valuable subject for ongoing study and exploration.

Synonyms
SCHEMBL6462735
GPXLMGHLHQJAGZ-UHFFFAOYSA-N
NS00009701
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2-ethoxy-1-naphthalenyl)carbonyl]amino]-3,3-dimethyl-7-oxo-, [2S-(2.alpha.,5.alpha.,6.beta.)]-
6-[(2-Ethoxy-1-naphthoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid #