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Amoxicillin

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Identification
Molecular formula
C16H19N3O5S
CAS number
26787-78-0
IUPAC name
6-[[2-(hydroxymethylamino)-2-phenyl-acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
State
State

Amoxicillin is a solid at room temperature. It is typically found in formulations such as tablets, capsules, or in powder form for suspension.

Melting point (Celsius)
194.00
Melting point (Kelvin)
467.00
Boiling point (Celsius)
292.00
Boiling point (Kelvin)
565.00
General information
Molecular weight
365.40g/mol
Molar mass
365.4000g/mol
Density
1.6000g/cm3
Appearence

Amoxicillin generally appears as a white or slightly yellow, crystalline powder. It is commonly used in the form of its trihydrate, which is water-soluble and appears as a white powder as well.

Comment on solubility

Solubility of 6-[[2-(hydroxymethylamino)-2-phenyl-acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

This compound presents intriguing solubility characteristics that are crucial for its application in various fields. The solubility of a compound can often be influenced by several factors, such as:

  • Polarity: The presence of functional groups such as hydroxymethyl and carboxylic acid groups increases its polarity, generally enhancing solubility in polar solvents like water.
  • Hydrogen bonding: The ability to form hydrogen bonds due to the hydroxymethyl and carboxylic acid groups can further contribute to its solubility in aqueous environments.
  • Structural complexity: The bicyclic structure and the presence of multiple functional groups in the compound affect the solubility. Compounds with complex structures may exhibit variations in solubility based on their conformation and intermolecular interactions.

Given these factors, it can be noted that:

  • The compound is likely soluble in polar solvents, making it potentially useful in biological applications where aqueous solubility is essential.
  • Its solubility may be limited in nonpolar solvents due to the inherent polar character of its functional groups.

In conclusion, while specific solubility data may vary, the structural elements of this compound suggest a favorable profile for solubility in polar environments, highlighting its potential for applications in pharmaceutical and biochemical settings.

Interesting facts

Interesting Facts About 6-[[2-(hydroxymethylamino)-2-phenyl-acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid

This intriguing compound, often recognized for its complex structure, holds a significant place in the realm of medicinal chemistry. Here are some fascinating insights into its attributes:

  • Structural Complexity: The presence of a bicyclic framework in this compound demonstrates the rich diversity of chemical architectures that can be synthesized. The bicyclo[3.2.0] moiety is particularly noteworthy for its unique three-dimensional arrangement.
  • Biological Significance: This compound has potential pharmaceutical applications, especially in the field of antibiotics. Its structure suggests it may interact effectively with biological targets, which could lead to the development of new therapies.
  • Functional Groups: The presence of various functional groups, including hydroxymethylamino and carboxylic acid, contributes to its reactivity and solubility, expanding the possibilities for chemical reactions and modifications.
  • Synthetic Pathways: The synthesis of such complex molecules often involves multi-step processes and significant synthetic ingenuity. Understanding these pathways is crucial for pharmaceutical applications.
  • Research Potential: Ongoing studies into the characteristics and interactions of this compound may unravel new mechanisms of action, making it a valuable subject for further investigations in both biochemistry and pharmacology.

As quoted by renowned chemists, “The beauty of organic chemistry lies in the intricacies of its molecules.” This compound is a perfect example of how such intricacies can lead to groundbreaking discoveries in the medical field.

In summary, the exploration of 6-[[2-(hydroxymethylamino)-2-phenyl-acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid not only highlights the wonders of chemical synthesis but also inspires countless research opportunities in designing effective therapeutic agents.