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Coomassie Brilliant Blue R-250

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Identification
Molecular formula
C45H44N3NaO7S2
CAS number
6104-58-1
IUPAC name
6-(2,4-diaminophenyl)azo-3-[4-[4-[[7-(2,4-diaminophenyl)azo-1-hydroxy-3-sulfo-2-naphthyl]azo]-2-sulfo-anilino]phenyl]azo-4-hydroxy-naphthalene-2-sulfonic acid
State
State

The compound is typically found as a solid powder at room temperature. It is stable and requires specific handling and storage conditions to prevent degradation.

Melting point (Celsius)
0.00
Melting point (Kelvin)
0.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
825.97g/mol
Molar mass
825.9710g/mol
Density
1.4195g/cm3
Appearence

Coomassie Brilliant Blue R-250 is a dark blue powder. It exhibits excellent dyeing ability and is commonly used in protein staining for polyacrylamide gel electrophoresis (SDS-PAGE).

Comment on solubility

Solubility of 6-(2,4-diaminophenyl)azo-3-[4-[4-[[7-(2,4-diaminophenyl)azo-1-hydroxy-3-sulfo-2-naphthyl]azo]-2-sulfo-anilino]phenyl]azo-4-hydroxy-naphthalene-2-sulfonic acid

The solubility of complex azo compounds, such as 6-(2,4-diaminophenyl)azo-3-[4-[4-[[7-(2,4-diaminophenyl)azo-1-hydroxy-3-sulfo-2-naphthyl]azo]-2-sulfo-anilino]phenyl]azo-4-hydroxy-naphthalene-2-sulfonic acid, can be influenced by various factors. Here are some key points regarding its solubility:

  • The presence of multiple functional groups, such as sulfonic acid and hydroxyl groups, typically enhances solubility in polar solvents like water.
  • Azo compounds often exhibit high affinity for aqueous solutions due to their ionic character and ability to form hydrogen bonds.
  • Pleurally charged moieties can lead to increased solubility, making this compound more readily soluble in environments that promote charge stabilization.

However, the overall solubility also depends on:

  1. The pH of the solution, as adjustments may lead to protonation or deprotonation of ionic groups.
  2. Temperature, which influences the kinetic energy of molecules, thereby affecting dissolution rates.
  3. The presence of other solutes, which can foster or inhibit solubility via electrostatic interactions or complex formation.

In conclusion, the solubility of this intricate azo compound in water should be considerable due to its polar functional groups, making it useful in various applications, including dyes and pigments. Nonetheless, further studies are necessary to ascertain the precise solubility profile under varied conditions.

Interesting facts

Interesting Facts about 6-(2,4-diaminophenyl)azo-3-[4-[4-[[7-(2,4-diaminophenyl)azo-1-hydroxy-3-sulfo-2-naphthyl]azo]-2-sulfo-anilino]phenyl]azo-4-hydroxy-naphthalene-2-sulfonic acid

This compound belongs to a class of chemicals known as azo dyes, which are renowned for their vibrant colors and extensive application in various fields. Azo dyes are characterized by the presence of the azo group (–N=N–) that links two aromatic moieties, contributing to their rich pigmentation.

Key Characteristics:

  • Diverse Applications: Azo dyes are widely used in textiles, food, inks, and cosmetics, providing bright colors while being cost-effective.
  • Environmental Concerns: Despite their utility, some azo dyes can be hazardous; they may produce toxic or carcinogenic aromatic amines upon degradation.
  • Color Variability: The specific structure of this compound includes multiple azo groups, allowing it to exhibit a variety of colors depending on the substituents present.

Azo dyes like this compound are particularly interesting to chemists because they:

  • Exhibit structure-dependent properties that can be finely tuned through chemical modification.
  • Often show photochromic behavior, changing color when exposed to light, making them useful in smart materials.
  • Have a historical significance, as they marked the transition from natural dyes to synthetic, revolutionizing the dye industry in the 19th century.

As students or scientists exploring this compound, you might appreciate the complexity of its structure that involves multiple layers of substitution patterns, enhancing the understanding of how molecular architecture influences the properties of chemical compounds. A great way to visualize this is through drawing its structure and predicting potential reactions or applications based on the specific functional groups present. In the world of dye chemistry, the combination of aesthetics and chemical reactivity opens up an exciting frontier for research and innovation.

Synonyms
76186-07-7
6-[2-(2,4-Diaminophenyl)diazenyl]-3-[2-[4-[2-[4-[[7-[2-(2,4-diaminophenyl)diazenyl]-1-hydroxy-3-sulfo-2-naphthalenyl]diazenyl]phenyl]amino]-3-sulfophenyl]diazenyl]-4-hydroxy-2-naphthalenesulfonic acid
6-(2-(2,4-Diaminophenyl)diazenyl)-3-(2-(4-(2-(4-((7-(2-(2,4-diaminophenyl)diazenyl)-1-hydroxy-3-sulfo-2-naphthalenyl)diazenyl)phenyl)amino)-3-sulfophenyl)diazenyl)-4-hydroxy-2-naphthalenesulfonic acid
2-NAphthalenesulfonic acid, 6-[2-(2,4-diaminophenyl)diazenyl]-3-[2-[4-[2-[4-[[7-[2-(2,4-diaminophenyl)diazenyl]-1-hydroxy-3-sulfo-2-naphthalenyl]diazenyl]phenyl]amino]-3-sulfophenyl]diazenyl]-4-hydroxy-
SCHEMBL14164004
SNOKTOUJNTYKIE-UHFFFAOYSA-N
DTXSID501028810
EINECS 278-387-2
6-((2,4-Diaminophenyl)azo)-3-((4-((4-((7-((2,4-diaminophenyl)azo)-1-hydroxy-3-sulpho-2-naphthyl)azo)phenyl)amino)-3-sulphophenyl)azo)-4-hydroxynaphthalene-2-sulphonic acid
6-(2,4-Diaminophenylazo)-3-[4-[4-[7-(2,4-diaminophenylazo)-1-hydroxy-3-sulfo-2-naphthalenylazo]phenylamino]-3-sulfophenylazo]-4-hydroxy-2-naphthalenesulfonic acid
NS00090025