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Cefuroxime

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Identification
Molecular formula
C16H16N4O8S
CAS number
55268-75-2
IUPAC name
6-[(2,6-dimethoxybenzoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
State
State

At room temperature, cefuroxime exists in a solid state as a crystalline powder. It is stable under normal conditions of temperature and pressure.

Melting point (Celsius)
169.00
Melting point (Kelvin)
442.15
Boiling point (Celsius)
624.00
Boiling point (Kelvin)
897.15
General information
Molecular weight
424.39g/mol
Molar mass
424.4360g/mol
Density
1.8120g/cm3
Appearence

The compound appears as a white to slightly yellow crystalline powder. It is often odorless and may come in the form of its sodium salt for medicinal uses. Under specific lighting conditions, it may appear slightly off-white.

Comment on solubility

Solubility of 6-[(2,6-dimethoxybenzoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

The solubility of 6-[(2,6-dimethoxybenzoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate (C16H16N4O8S) can be influenced by its chemical structure and functional groups. Understanding its solubility is crucial for its applications and behavior in various environments. Here are some key points to consider:

  • Polarity: The presence of multiple functional groups, including carbonyls and methoxy groups, suggests varying polarities, which may enhance its solubility in polar solvents.
  • Hydrogen Bonding: The amine and carboxylate groups can participate in hydrogen bonding, potentially increasing solubility in polar solvents, such as water.
  • Solvent Interaction: It may exhibit different solubilities depending on the solvent used. For instance, it could be more soluble in organic solvents like ethanol or acetone than in non-polar solvents.
  • Temperature Dependency: Solubility often increases with temperature; hence, evaluating this compound's solubility at various temperatures might yield interesting results.

In summary, while specific solubility data may not be readily available, one can predict that 6-[(2,6-dimethoxybenzoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate could exhibit moderate solubility in polar solvents primarily due to its ability to engage in interactions like hydrogen bonding. Such characteristics make it a candidate for further investigation in relevant chemical applications.

Interesting facts

Exploring 6-[(2,6-dimethoxybenzoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

This fascinating compound, often subjected to research in the fields of medicinal chemistry and pharmacology, exhibits a unique structural configuration characterized by its bicyclic framework and functional groups. Here are some captivating facts about this compound:

  • Biological Significance: It is studied for its potential biological activities, particularly its antimicrobial and antitumor properties, making it a candidate for drug development.
  • Structural Dynamics: The bicyclic structure plays a crucial role in how the compound interacts with biological targets, influencing its biological efficacy.
  • Functional Groups: The presence of dimethoxy and amino groups can enhance the compound's solubility and permeability, impacting its medicinal use.
  • Research Potential: Researchers continue to explore its derivatives and analogs to optimize efficacy and minimize side effects.
  • Synthetic Pathways: The synthesis of this compound involves advanced *organic chemistry techniques*, which can include various coupling reactions and cyclization processes.

The exploration of 6-[(2,6-dimethoxybenzoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate illustrates the complexity and ingenuity of modern chemistry, as scientists strive to understand and harness the potential of such compounds for therapeutic applications. As one researcher aptly stated, "The key to advancing medicinal chemistry lies in the intricate dance of structure and function."

By delving deeper into compounds like this, we can unlock new opportunities for innovative treatments in the realm of healthcare.