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Cefaclor

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Identification
Molecular formula
C15H14ClN3O4S
CAS number
53994-73-3
IUPAC name
6-[[3-(2-chlorophenyl)-5-methyl-isothiazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
State
State

At room temperature, Cefaclor is in a solid state, specifically in the form of a crystalline powder.

Melting point (Celsius)
187.00
Melting point (Kelvin)
460.15
Boiling point (Celsius)
342.00
Boiling point (Kelvin)
615.15
General information
Molecular weight
368.84g/mol
Molar mass
368.8410g/mol
Density
1.5900g/cm3
Appearence

Cefaclor typically appears as a white to off-white crystalline powder. It is practically odorless and is very soluble in water, while slightly soluble in methanol and ethanol.

Comment on solubility

Solubility Insights for 6-[[3-(2-chlorophenyl)-5-methyl-isothiazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

The solubility of the compound 6-[[3-(2-chlorophenyl)-5-methyl-isothiazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid can be influenced by several factors:

  • Polarity: The presence of both hydrophilic (amino and carboxylic acid groups) and hydrophobic (isothiazole and chlorophenyl moieties) characteristics can lead to variable solubility in different solvents.
  • Solvent Type: It is more likely to be soluble in polar solvents such as water and alcohols due to its functional groups, whereas it may exhibit lower solubility in non-polar solvents.
  • pH Influence: The solubility can also be pH-dependent, as ionization of carboxylic acid and amino groups may enhance the solubility in basic conditions.
  • Interactions: Hydrogen bonding and Van der Waals forces can further modify its solubility profile depending on the surrounding environment.

In conclusion, the solubility of this compound is a complex interplay of its molecular structure and environmental conditions, making it essential to consider these aspects when predicting its behavior in various solvents.

Interesting facts

Interesting Facts about 6-[[3-(2-chlorophenyl)-5-methyl-isothiazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

This unique compound is a member of a family of chemical structures known for their impressive range of biological activities. Specifically, its complex architecture—characterized by the presence of an isothiazole ring, as well as bicyclic structures—allows it to interact with various biological targets, making it a subject of interest in medicinal chemistry.

Key Features:

  • Diverse Applications: Compounds like this often showcase potential in pharmaceutical developments, particularly as antimicrobial agents and anticancer drugs.
  • Structural Diversity: The incorporation of different functional groups, such as the 2-chlorophenyl ring and a carboxylic acid moiety, enhances its biological activity and can lead to improved interactions within biological systems.
  • Mechanistic Insights: The combination of an isothiazole ring with a bicyclic framework may reflect mechanisms that inhibit specific enzymes, potentially leading to therapeutic benefits.

As highlighted by researchers, "The interplay of various molecular features within structures like this compound reveals pathways for novel therapeutic development." This statement underscores the ongoing exploration of structure-activity relationships essential in drug design.

Lastly, with the ever-growing need for new therapeutics, understanding compounds with such intricate structures can pave the way for significant advancements in treating diseases that current medications might not effectively address.